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Patent
Shanghai Hengrui Pharmaceutical Co. and Jiangsu Hengrui Medicine Co. | Date: 2013-08-26

New imidazoline derivatives represented by formula (I): preparation methods thereof, pharmaceutical compositions comprising such derivatives, and applications of such derivatives in preparing androgen receptor antagonists and medicaments for treating diseases such as prostate cancer are described.


Patent
Shanghai Hengrui Pharmaceutical Co. and Jiangsu Hengrui Medicine Co. | Date: 2014-01-27

The pharmaceutically acceptable salts of bicycle-substituted pyrazolon azo derivatives represented by the general formula (I), their preparation methods, pharmaceutical compositions containing the same and their use as a therapeutic agent, especially as thrombopoietin (TPO) mimetics and their use as agonists of thrombopoietin receptor. The definitions of substituents in the general formula (I) are the same as the description.


Patent
Shanghai Hengrui Pharmaceutical Co. | Date: 2011-08-02

The present invention relates to pyrrolo[3,2-c]pyridine-4-one 2-indolinone compounds of Formula (I) and their pharmaceutically acceptable salts thereof, wherein R


Patent
Shanghai Hengrui Pharmaceutical Co. and Jiangsu Hengrui Medicine Co. | Date: 2012-05-03

Tetrahydro-imidazo[1,5-a]pyrazine derivatives of formula (I), their preparation methods, pharmaceutical compositions containing the derivatives and uses thereof as medicaments, especially as dipeptidyl peptidase IV inhibitors, wherein the substituents of formula (I) are defined as same as the description.


Patent
Shanghai Hengrui Pharmaceutical Co. and Jiangsu Hansoh Pharmaceutical Co. | Date: 2012-09-27

The invention provides a method of inhibiting the catalytic activity of a protein kinase comprising contacting said protein kinase with a compound of formula (I), or a pharmaceutically acceptable salt thereof, or a pharmaceutical composition containing the same, and also provides a method of treating a protein kinase related disorder comprising a step of administering to a patient in need thereof a therapeutically effective amount of the compound of formula (I) or a pharmaceutically acceptable salt thereof, or a pharmaceutical composition containing the same, wherein each substituent in formula (I) is same as defined in the description.

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