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Jinan, China

Shandong University is a public comprehensive university in Shandong, China. It is one of the largest universities in China by student population and is supported directly by the national government.Present-day Shandong University is the result of multiple mergers as well as splits and restructurings that have involved more than a dozen academic institutions over time. The oldest of Shandong University's precursor institutions, Cheeloo University, was founded by American and English mission agencies in the late 19th century . Tengchow College was the first modern institution of higher learning in China. Shandong University derives its official founding date from the Imperial Shandong University established in Jinan in November 1901 as the second modern national university in the country.Shandong University has seven campuses, all but one of which are located in the provincial capital city of Jinan. A campus to the northeast of the port city of Qingdao is under construction. The university has been classified as a National Key University by the Chinese Ministry of Education since 1960. It has been included in major national initiatives seeking to enhance the international competitiveness of the top-tier universities in China such as Project 985 and Project 211.Shandong University offers master and doctoral degree programs in all major academic disciplines covering the humanities, science and engineering, as well as medicine. Wikipedia.

Energetic ion beams with diverse energies, species and beam dimensions have been extensively utilized to modify the properties of materials to achieve versatile applications in many aspects of industry, agriculture and scientific research. In optics, the ion-beam technology has been applied to fabricate various micro- and submicrometric guiding structures on a wide range of optical crystals through the efficient modulation of the refractive indices or structuring of the surface, realizing various applications in many branches of photonics. The ion-beam fabricated optical waveguides and other photonic structures have shown good guiding performance as well as properties related to the materials, suggesting promising potential for many aspects of photonics. This paper gives the state-of-the-art review of fabrication, characterization and application on the ion-beam-processed micro- and submicrometric photonic structures by highlighting the most recent research progress. A brief prospect is presented by focusing on a few potential spotlights. © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. Source

Tong D.M.,Shandong University
Physical Review Letters | Year: 2010

The quantitative condition has been widely used in the practical applications of the adiabatic theorem. However, it had never been proved to be sufficient or necessary before. It was only recently found that the quantitative condition is insufficient, but whether it is necessary remains unresolved. In this Letter, we prove that the quantitative condition is necessary in guaranteeing the validity of the adiabatic approximation. © 2010 The American Physical Society. Source

Cui M.,Shandong University
Journal of Computational Physics | Year: 2012

High-order compact finite difference scheme with operator splitting technique for solving two-dimensional time fractional diffusion equation is considered in this paper. A Grünwald-Letnikov approximation is used for the Riemann-Liouville time derivative, and the second order spatial derivatives are approximated by the compact finite differences to obtain a fully discrete implicit scheme. Alternating direction implicit (ADI) method is used to split the original problem into two separate one-dimensional problems. The local truncation error is analyzed and the stability is discussed by the Fourier method. The proposed scheme is suitable when the order of the time fractional derivative γ lies in the interval 12,1. A correction term is added to maintain high accuracy when γ∈0,12. Numerical results are provided to verify the accuracy and efficiency of the proposed algorithm. © 2011 Elsevier Inc. Source

Zhao W.,Shandong University
FEBS Letters | Year: 2013

TANK-binding kinase 1 (TBK1) plays pivotal roles in antiviral innate immunity. TBK1 mediates the activation of interferon regulatory factor (IRF) 3, leading to the induction of type I IFNs (IFN-α/β) following viral infections. TBK1 must be tightly regulated to effectively control viral infections and maintain immune homeostasis. TBK1 activity can be regulated in a variety of ways, such as phosphorylation, ubiquitination, kinase activity modulation and prevention of functional TBK1-containing complexes formation. Furthermore, multiple viruses have evolved elaborate strategies to circumvent IFN responses by targeting TBK1. Here we provide an overview of TBK1 in antiviral immunity and recent developments on the regulation of TBK1 activity. © 2013 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved. Source

Wang Y.,CAS Yantai Institute of Coastal Zone Research | Yan B.,Shandong University | Chen L.,CAS Yantai Institute of Coastal Zone Research
Chemical Reviews | Year: 2013

Surface-enhanced Raman scattering (SERS) is an ultrasensitive vibrational spectroscopic technique to detect molecules on or near the surface of plasmonic nanostructures, greatly extending the role of standard Raman spectroscopy. Since its discovery in the 1970s, SERS has been applied to many analyses, especially in biochemistry and life sciences. Surface-enhanced Raman scattering (SERS) is an ultrasensitive vibrational spectroscopic technique to detect molecules on or near the surface of plasmonic nanostructures, greatly extending the role of standard Raman spectroscopy. The first explanation is that the molecule-surface interaction induces novel charge-transfer intermediates that have higher Raman scattering cross sections than do those of the analyte that is unadsorbed and on the surface. Source

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