Shandong Provincial Key Laboratory of Glycoscience and Glycotechnology

Qingdao, China

Shandong Provincial Key Laboratory of Glycoscience and Glycotechnology

Qingdao, China

Time filter

Source Type

Wang Y.,Ocean University of China | Yu G.,Ocean University of China | Yu G.,Shandong Provincial Key Laboratory of Glycoscience and Glycotechnology | Han Z.,Shandong Provincial Key Laboratory of Glycoscience and Glycotechnology | And 4 more authors.
Acta Chimica Sinica | Year: 2011

Nine oligosaccharides were obtained from agarose by chemical and enzymatic degradation and gel filtration chromatography. All oligosaccharides were linked to 1, 2-dihexadecyl-sn-glycero-3-phosphoethanolamine (DHPE) by a reductive animation reaction to acquire neoglycolipids. Compared with standard oligosaccharides (LNnT and LNT), the affinity of agaro-oligosaccharides to RCA120 was studied using glycochip technique. We firstly found the higher affinity of oligosaccharides with structure of Galβ1, 4AnG-R than that of Galβ 1, 4GlcNAc-R to RCA120 compared with LNnT, and the affinity have no relation with degree of polymerization.

Loading Shandong Provincial Key Laboratory of Glycoscience and Glycotechnology collaborators
Loading Shandong Provincial Key Laboratory of Glycoscience and Glycotechnology collaborators