Khairpur, Pakistan

Shah Abdul Latif University

www.salu.edu.pk
Khairpur, Pakistan

Shah Abdul Latif University , is a public research university located in rural Khairpur of Sindh, Pakistan. The university is named after the mystic poet and spiritualist Shah Abdul Latif Bhittai.The university also maintains a teaching campus in Shikarpur, Sindh, Pakistan. Founded in 1976 as a single campus, the university has grown in both keeping its reputation and physical enlargement whilst developing a strong and transparent system of higher education in the north of Sindh. The university offers undergraduate, post-graduate, and doctorate programmes in various academic disciplines. The university is noted for its academic staff consisting of foreign scholars, and research directed towards the development of humanities, archaeology, Sindh studies, natural and social science.In addition, it is ranked as one of the top institution of high learning by the HEC on "general" category. Nearly ~7000 students currently enrolled in the university, the university's main focus is committed to enabling its graduates to lead and serve the nation apart from their own better well-being. Wikipedia.


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Ahmed I.,University of Central Lancashire | Ahmed I.,Shah Abdul Latif University | Ly D.Q.,University of Central Lancashire | Ly D.Q.,Brunel University | Ahmed W.,University of Central Lancashire
Materials Today: Proceedings | Year: 2017

The concept of self-propelled particles are widely used to various applications of bio nanotechnology, thus by exploiting this strategy they can be further designed as a strategy to enhance target specific drug delivery. Self-propelled particles can show important non equilibrium behaviour, and how they interact with moving obstacles has remained an open problem. In this work we introduce a new model which investigates the collective behaviour of the self-propelled particles in the presence of moving obstacles in heterogeneous medium. Effect of obstacle density, avoidance radius, and noise on the collective motion of the self-propelled particles is investigated. The findings of this study suggested that, with the smaller noise there was cohesion in the system and particles exhibited cluster formation whereas in the case of higher noise particles showed loss of cohesion and there existed no collective motion. Variations in the avoidance radius and obstacle density brought non-monotonic behaviour in the system. © 2017 Elsevier Ltd. All rights reserved.


Kazi Y.F.,Shah Abdul Latif University | Saleem S.,Shah Abdul Latif University | Kazi N.,University of Sindh
BMC Urology | Year: 2012

Background: Previous studies report association of contraceptives with moderate increase in urinary tract infection among sexually active premenopausal women. The aim of our study was to find out whether the use of hormonal contraceptives has any effect on microbiota of the vagina in the contraceptives users in Khairpur Sindh Pakistan. Methods. A prospective study in woman population of Khairpur Sindh Pakistan aged 20-30 years and 31-40 years, using Hormonal contraceptives was carried out. High vaginal swab samples (n=100) were collected from the test populations as well as control group (n=100) and investigated for vaginal microbial flora using standard microbiological and biochemical techniques. Results: Vaginal swabs culturing from hormonal contraceptives users in the age group 20-30 years showed statistically insignificant Candida sp (10% samples), and statistically significant (p<0.05) Staphylococcus saprophyticus. (18% samples), Streptococcus agalactiae (23% samples), Escherichia coli (28% samples) and Lactobacillus fermentum (32% samples). In the age group 31-40 years, statistically significant percentage of samples (p<0.05) showed Lactobacillus fermentum (28%), Candida sp (24%), and E. coli, (24%) where statistically insignificant samples showed Staphylococcus saprophyticus (13%) and Streptococcus agalactiae (11%). Conclusions: The use of hormonal contraceptives alters the normal microbiota of vagina in women according to the age. Lactobacillus fermentum appeared as the predominant species followed by E. coli among the age group of 20-30 years and, Lactobacillus fermentum, Candida sp and E. coli as predominant among women of age group 31-40 years when compared to corresponding control groups. An inverse relationship between E. coli and Lactobacillus fermentum was observed in the women aged 20-30 years. © 2012 Kazi et al.; licensee BioMed Central Ltd.


Qureshi R.,Pmas Arid Agriculture University | Raza Bhatti G.,Shah Abdul Latif University | Memon R.A.,University of Sindh
Pakistan Journal of Botany | Year: 2010

Ethnobotanical survey of Nara Desert, Sindh, Pakistan was carried out during 1998-2001. Local inhabitants are extremely knowledgeable about the utilization of indigenous flora of the study area. They use them in fever, flue, cough, asthma, digestive troubles, piles, diabetes, urinary diseases, male sexual diseases, gynecological diseases, joints pain/rheumatic pains and inflammation, ear diseases, tooth problems, cuts and wounds, skin diseases, cooling agents and miscellaneous uses. In the present communication, 63 plant species belonging to 50 genera and 29 families are included. The major plant families which contributed in folk herbs included Fabaceae (7 spp.), Boraginaceae (6 spp.), Amaranthaceae (5 spp.) and Cucurbitaceae (4 spp.). For each species, botanical name, vernacular name, part(s) used, medicinal use, method of preparation and applications of the herbal remedies are provided.


Mughal A.,Shah Abdul Latif University | Kazi Y.F.,Shah Abdul Latif University | Bukhari H.A.,COMSATS Institute of Information Technology | Ali M.,COMSATS Institute of Information Technology
Public Health | Year: 2012

Objectives: To investigate the aetiology of persistent cough among vaccinated children as suspected cases of pertussis in Khairpur District, Sindh, Pakistan. Pertussis or whooping cough, caused by . Bordetella pertussis, is re-appearing in many countries despite vaccination coverage. In Khairpur, persistent cough and symptoms similar to pertussis among vaccinated children are common but the aetiology has not been investigated previously. Study design: B. pertussis was isolated from cough samples of suspected pertussis patients (. n = 700) using the cough plate method with charcoal agar. Methods: Isolation and confirmation of the clinical isolates of . B. pertussis was performed by culture on Bordet-Gengou medium, biochemical tests and polymerase chain reaction. Results: In total, 22 strains of . B. pertussis were isolated from clinical cough samples. Conclusion: To the authors' knowledge, this is the first report of the presence of pertussis in vaccinated children in Khairpur. There is a need for continuous monitoring of pertussis after immunization programmes in order to assess the efficacy of pertussis vaccination. © 2012 The Royal Society for Public Health.


Qureshi R.,Pmas Arid Agriculture University | Bhatti G.R.,Shah Abdul Latif University | Shabbir G.,Pmas Arid Agriculture University
Pakistan Journal of Botany | Year: 2011

The aim of present study was to provide botanical inventory of the study area. For this purpose, floristic survey was carried out during April, 2008 to March, 2009. One hundred thirty plant species belonging to 105 genera and 37 families were identified from the study area. Of them, 97 species were of dicot and 33 monocot. Poaceae was found the most dominant family in the flora of the Koont Farm that contributed 23.26% followed by Asteraceae (13.18%), Fabaceae (7.75%), Amaranthaceae, Euphorbiaceae (6.25% each), Solanaceae (4.65%) and Boraginaceae (3.10%), while rest of the families had few species. It has been observed that most of the life-span of recorded taxa was annual natured (52%) followed by perennial (40%) and biennial (8%). Therophytes were the most abundant life form that constituted 43% of the total flora, followed by phanerophytes (19%), cryptophytes (15%), hemicryptophytes (13%) and xeropsammophytes (10%).


Malik Z.A.,Shah Abdul Latif University | Ahmed S.,Quaid-i-Azam University
African Journal of Biotechnology | Year: 2012

A mixed consortium was prepared with 15 bacteria isolated by enrichment technique from the sample collected from an oil contaminated site. This consortium was incubated with crude oil to investigate the metabolic capability of bacteria. The degradation efficiency of the isolates in consortium was checked with 2% crude oil by shake flask transformation in mineral salt medium, at 37°C for 24 days. Total removal of aliphatic and aromatics was 94.64% and 93.75% respectively. Among the various components of the crude oil degradation by the bacterial consortium, the biotic removal of alkanes was maximum, 90.96% for tridecane (C 13) followed by pentadecane (C 15) at 77.95%, octadecane (C 18) at 74.1%, while other alkanes showed 56 to 69% after 24 days of incubation. The aromatics (benzene, toluene and xylene) were vaporized in the 4th day of incubation, while the efficiency on polyaromatic fractions (anthracene, phenanthrene and pyrene) was 46.17 to 55.3% after 24 days. The ability of degrading long chain n-alkanes and crude oil at high concentrations makes the consortium potentially useful for bioremediation and microbial enhanced oil recovery. © 2012 Academic Journals.


Memon B.A.,Shah Abdul Latif University
Journal of the Chemical Society of Pakistan | Year: 2012

The effect of desferal (Desferrioxamine) on the growth of Streptococcus-pyogenes group A and Staphylococcus aureus was investigated. A large molar excess of desferal over Fe in the medium had no effect on the strains of Streptococcus pyogenes group A. Staphylococcus aureus was inhibited at 20:1 molar excess of desferal over Fe suggesting bactericidal effect. All strains of Streptococcus pyogenes group A were unaffected by 20:1 molar excess desferal suggesting that Streptococcus pyogenes group A was insensitive to even large molar excess of desferal and absence of siderophore production suggested either iron-independent growth or extraordinary efficient Fe acquisition or low Fe requirement as compared to Staphylococcus aureus.


Nawaz Z.,Zhejiang University | Kakar K.U.,Zhejiang University | Saand M.A.,Shah Abdul Latif University | Shu Q.-Y.,Zhejiang University
BMC Genomics | Year: 2014

Background: Cyclic nucleotide-gated channels (CNGCs) are Ca2+-permeable cation transport channels, which are present in both animal and plant systems. They have been implicated in the uptake of both essential and toxic cations, Ca2+ signaling, pathogen defense, and thermotolerance in plants. To date there has not been a genome-wide overview of the CNGC gene family in any economically important crop, including rice (Oryza sativa L.). There is an urgent need for a thorough genome-wide analysis and experimental verification of this gene family in rice.Results: In this study, a total of 16 full length rice CNGC genes distributed on chromosomes 1-6, 9 and 12, were identified by employing comprehensive bioinformatics analyses. Based on phylogeny, the family of OsCNGCs was classified into four major groups (I-IV) and two sub-groups (IV-A and IV- B). Likewise, the CNGCs from all plant lineages clustered into four groups (I-IV), where group II was conserved in all land plants. Gene duplication analysis revealed that both chromosomal segmentation (OsCNGC1 and 2, 10 and 11, 15 and 16) and tandem duplications (OsCNGC1 and 2) significantly contributed to the expansion of this gene family. Motif composition and protein sequence analysis revealed that the CNGC specific domain " cyclic nucleotide-binding domain (CNBD)" comprises a " phosphate binding cassette" (PBC) and a " hinge" region that is highly conserved among the OsCNGCs. In addition, OsCNGC proteins also contain various other functional motifs and post-translational modification sites. We successively built a stringent motif: (LI-X(2)-[GS]-X-[FV]-X-G-[1]-ELL-X-W-X(12,22)-SA-X(2)-T-X(7)-[EQ]-AF-X-L) that recognizes the rice CNGCs specifically. Prediction of cis-acting regulatory elements in 5′ upstream sequences and expression analyses through quantitative qPCR demonstrated that OsCNGC genes were highly responsive to multiple stimuli including hormonal (abscisic acid, indoleacetic acid, kinetin and ethylene), biotic (Pseudomonas fuscovaginae and Xanthomonas oryzae pv. oryzae) and abiotic (cold) stress.Conclusions: There are 16 CNGC genes in rice, which were probably expanded through chromosomal segmentation and tandem duplications and comprise a PBC and a " hinge" region in the CNBD domain, featured by a stringent motif. The various cis-acting regulatory elements in the upstream sequences may be responsible for responding to multiple stimuli, including hormonal, biotic and abiotic stresses. © 2014 Nawaz et al.; licensee BioMed Central Ltd.


Memon B.A.,Shah Abdul Latif University
Journal of the Chemical Society of Pakistan | Year: 2010

Streptolysin S (SLS) produced by group A Streptococcus (GAS) is very potent membrane-damaging agent and lyses a wide variety of living cells and organelles. This study is about the comparison between the relative sensitivity of sheep red blood cells (haemolytic assay) and that of rabbit peritoneal neutrophils (chemiluminescence assay) towards the purified SLS. Purified SLS. at concentrations of between 8000 HU/ml and 256 HU/ml. when added directly to FMLP-induced rabbit PMNs. caused inhibition of the PMNs chemiluminescence response This study concludes that on a cell basis, sheep red blood cells are 1.2x105 fold more sensitive to SLS than PMNs.


Qureshi R.,Pmas Arid Agriculture University | Bhatti G.R.,Shah Abdul Latif University
Pakistan Journal of Botany | Year: 2010

The main objective of this study was to record the existing floral diversity of Pai forest, Nawab Shah, Sindh, Pakistan. For this purpose, field surveys were conducted in September, 2006 and March, 2009. A total of 93 plant species belonging to 67 genera and 30 families were identified. Poaceae was the largest family that contributed 14 species (15.05%), followed by Amaranthaceae with 7 species (7.53%), Capparidaceae and Tiliaceae with 5 spp., (5.38% each); while 7 families contributed 4 species (4.30%). The most common life form class of the existing flora was Phanerophyte with the large number of species (37), followed by Therophyte (33), Chaemophytes (12), Hemicryptophyte (6) and Cryptophyte (3). The anthropogenic activities coupled with irrigation water deficit and allelopathic behavior of alien species (Prosopis juliflora) led to decline the natural ecosystem of this plantation.

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