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Kitakyūshū, Japan

Hiroshima University and Shabondama Soap Co. | Date: 2010-04-16

It is an object to provide an antiviral agent that can be used for persons having sensitive skin or on the face, inactivates viruses such as a norovirus and an influenza virus, and is excellent in germicidal properties. Further provided is a cleansing agent that does not lead to environmental pollution since the cleansing agent is easily decomposed in the natural environment, scarcely causes eczema and allergic dermatitis since no germicidal agent is added, and has an antiviral performance. The antiviral agent containing a surface-active agent having a C18 unsaturated alkyl group as an active component. It is not always necessary to lather or rinse off with water like cleansing agents such as medicated soaps since the antiviral agent of the present invention at a very low concentration can inactivate the virus.

SHABONDAMA SOAP Co. | Date: 2007-01-23

Soaps and detergents [ ; dentifrices; laundry bleach ].

SHABONDAMA SOAP Co. | Date: 2007-01-02

Soaps and detergents [, dentifrices; laundry bleach ].

Masuda M.,University of Kitakyushu | Era M.,University of Kitakyushu | Kawahara T.,Shabondama Soap Co. | Kanyama T.,Shabondama Soap Co. | Morita H.,University of Kitakyushu
Biocontrol Science | Year: 2015

Fatty acid salts are a type of surfactant known to have potent antibacterial activity. We therefore examined the antibacterial activities of fatty acid salts against Streptococcus mutans. Potassium caprylate (C10K) , potassium laurate (C12K) , potassium myristate (C14K) , potassium oleate (C18:1K) , potassium linoleate (C18:2K) , and potassium linolenate (C18:3K) , used at a concentration of 175 mM, resulted in a 7 log-unit reduction of S. mutans after a 10-min incubation. The minimum inhibitory concentration (MIC) of C18:2K and C18:3K was 5.5 mM. C12K also demonstrated high antibacterial activity (MIC of 21.9 mM). These results indicate that C12K, C18:2K, and C18:3K have high antibacterial activity against S. mutans, and possess great potential as antibacterial agents.

Era M.,University of Kitakyushu | Sakai S.,University of Kitakyushu | Tanaka A.,University of Kitakyushu | Kawahara T.,Shabondama Soap Co. | And 2 more authors.
Japan Journal of Food Engineering | Year: 2015

The antifungal activity of nine fatty acid salts (butyrate, caproate, caprylate, caprate, laurate, myristate, oleate, linoleate, and linolenate) was tested on the spores of Penicillium pinophilum NBRC 6345 and Penicillium digitatum NBRC 9651. Potassium caprate showed the strongest antifungal activity at 4 log-units. At incubation times of 180 min, potassium caprylate and potassium laurate showed antifungal activities of 2 log-units against P. pinophilum NBRC 6345. These results suggest medium-chain fatty acid salts showed the highest antifungal activity. The minimum inhibitor y concentration of potassium caprate against P. pinophilum NBRC 6345 was 175 mM, and >175 mM for other fatty acid salts. When mixed with short-chain fatty acid salts (potassium butyrate, potassium caproate) or medium-chain fatty acid salts (potassium caprylate or potassium laurate), potassium caprate caused a 4 log-unit reduction in fungal growth; however, when mixed with long-chain fatty acid salts (potassium myristate, potassium oleate, potassium linoleate, or potassium linolenate) it had no antifungal effect. Thus, long-chain fatty acid salts inhibited antifungal activity of C10K. We also evaluated the ability of C10K to inhibit fungal growth on orange rind. C10K effectively inhibited P. pinophilum NBRC 6345 growth on orange rind. Thus, C10K shows promise as an antifungal agent. © 2015, Japan Society for Food Engineering. All rights reserved.

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