Xianyang, China

Shaanxi University of Chinese Medicine is located in Xianyang, the first capital of China in history. The university has two campuses, with a total area of 616024.4 m2. It was confirmed by the central government in 1978 to be one of the key universities for Chinese medicine, and was among the earliest medical universities that were authorized by the Ministry of Education in 1981 to grant master’s degree. (Note: The name “Shanxi University of Chinese Medicine” is a different university. "Shaanxi" and "Shanxi" are two provinces of China.) Wikipedia.


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Wang C.-H.,Shaanxi Institute for Food and Drug Control | Wang Y.-X.,Shaanxi University of Chinese Medicine | Liu H.-J.,Shaanxi Institute for Food and Drug Control
Journal of Pharmaceutical Analysis | Year: 2011

A simple, precise, and rapid high-performance liquid chromatographic method was developed and validated for the simultaneous determination of vitexin-2″-O-glucoside, vitexin-2″-O-rhamnoside, rutin, vitexin, and hyperoside. The HPLC separation was performed using a Shim-pack VP-ODS C 18 column (250 mm×4.6 mm i.d., 5 μm) with the isocratic mobile phase consisting of tetrahydrofuran/ acetonitrile/0.05% phosphoric acid solution (20:3:77, v/v/v), and the flow rate was set at 1.0 mL/min. UV detection was carried out at a wavelength of 360 nm and the whole analysis took 25 min. The method was linear in the range of 4.12206.00 μg/mL for vitexin-2″-O-glucoside, 4.05202.50 μg/mL for vitexin-2″-O- rhamnoside, 1.6482.00 μg/mL for rutin, 1.7487.00 μg/mL for vitexin, and 1.4170.60 μg/mL for hyperoside with the correlation coefficient for each analyte more than 0.998. The limit of detection (LOD) and limit of quantitation (LOQ) were 0.6 and 2 ng for vitexin-2″-O-glucoside, 0.6 and 2 ng for vitexin-2″-O-rhamnoside, 0.3 and 1 ng for rutin, 1 and 3 ng for vitexin, and 0.5 and 2 ng for hyperoside, respectively. Intra- and inter-day precision and accuracy (RSD) were less than 3%. The developed HPLC method was successfully applied to the analysis of five flavonoids in hawthorn leaves, hawthorn fruits, and the preparations containing hawthorn leaves or fruits. © 2011 Xi'an Jiaotong University. Production and hosting by Elsevier B.V. All rights reserved.


Wang T.,University of Tennessee Health Science Center | Wang B.,Shaanxi University of Chinese Medicine
Journal of the Neurological Sciences | Year: 2014

The Glutathione S-transferase M1 (GSTM1) and Glutathione S-transferase T1 (GSTT1) genes have been studied extensively as potential candidate genes for the risk of Parkinson's disease (PD). However, direct evidence from genetic association studies remains inconclusive. In order to address this issue, we performed an updated and refined meta-analysis to determine the effect of GSTM1 and GSTT1 polymorphisms on Parkinson's disease. A fixed-effect model was utilized to calculate the combined odds ratio (OR), OR of different ethnicities, and 95% confidence intervals (CIs). Potential publication bias was estimated. Homogeneity of the included studies was also evaluated. The pooled OR was 1.13 [95% CI (1.03, 1.24)] and 0.96 [95% CI (0.82, 1.12)] for GSTM1 and GSTT1 polymorphisms, respectively. Analysis according to different races found no association between GSTM1/GSTT1 polymorphisms and PD risks except for GSTM1 variant in Caucasians, which showed a weak correlation (OR 1.16 [95% CI (1.04, 1.29), I squared = 6.2%, p = 0.384]). Neither publication bias nor heterogeneity was found among the included studies. The results of this meta-analysis suggest that GSTM1 polymorphism is weakly associated with the risk of PD in Caucasians whereas GSTT1 polymorphism is not a PD risk factor. © 2013 Elsevier B.V.


Wang X.,Shaanxi University of Chinese Medicine | Lin H.,Shaanxi University of Chinese Medicine | Gu Y.,North Dakota State University
Lipids in Health and Disease | Year: 2012

Considerable arguments remain regarding the diverse biological activities of polyunsaturated fatty acids (PUFA). One of the most interesting but controversial dietary approaches focused on the diverse function of dihomo-dietary -linolenic acid (DGLA) in anti-inflammation and anti-proliferation diseases, especially for cancers. This strategy is based on the ability of DGLA to interfere in cellular lipid metabolism and eicosanoid (cyclooxygenase and lipoxygenase) biosynthesis. Subsequently, DGLA can be further converted by inflammatory cells to 15-(S)-hydroxy-8,11,13-eicosatrienoic acid and prostaglandin E 1 (PGE 1). This is noteworthy because these compounds possess both anti-inflammatory and anti-proliferative properties. PGE1 could also induce growth inhibition and differentiation of cancer cells. Although the mechanism of DGLA has not yet been elucidated, it is significant to anticipate the antitumor potential benefits from DGLA. © 2012 Wang et al; licensee BioMed Central Ltd.


Lv Q.-L.,Shaanxi University of Chinese Medicine
Chinese Traditional and Herbal Drugs | Year: 2016

The traditional Chinese medicine (TCM) as a treasure of the Chinese history, has deposited lots of precious experience and valuable data. As an effective mean of data processing and knowledge discovery, data mining and complex networks are used to describe the data from the statistics and complexity, and are widely used in the research of modern TCM. Data mining bias to explore the surface of the statistical law, lack for an in-depth discussion of the inner mechanism of the system; While the complex network mainly describes the system structure through the perspective of network and good at exploring the universal law in the functional complexity, but there are limitations in the large data processing. To analyze on the applications and problems of data mining and complex networks in the field of TCM, give two methods and frame of paradigms integration, construct Chinese medicine property development network in case of cerebral vascular disease, and excavate the regularity of compatibility of TCM combined with pharmaceutical association and improved COPRA algorithm. The experimental results show that the method can effectively explore the association rules of the infrequent itemsets, and provide the basis for the compatibility of Chinese herbal medicine. © 2016, Editorial Office of Chinese Traditional and Herbal Drugs. All right reserved.


Hou Z.,Shaanxi University of Chinese Medicine
Chemical Engineering Transactions | Year: 2016

The magnesium alloys AZ91-0.15Y used in sports apparatus were prepared through common casting and pressurized differential pressure casting respectively and the microstructure and fatigue property were investigated. It turns out that compared with common casting; pressurized differential pressure casting conspicuously refines the microstructure of the alloy, leading to a better fatigue property. In addition, the fatigue fracture transforms from brittle fracture resulted from common casting to the mixed trait of cleavage and ductile fracture resulted from pressurized differential pressure casting. Copyright © 2016, AIDIC Servizi S.r.l.


Zhang H.,Shaanxi University of Chinese Medicine
International Journal of Multimedia and Ubiquitous Engineering | Year: 2016

In this paper, we analyze the impact factors of college students' physical exercise by using probability sampling method; the data was collected based on the non-probabilistic method of network experimental investigation. The survey shows that physical exercise can bring joy and vitality to people's life, and will improve the quality of life. The data shows that 22.4% students have formed the habit of sports; also 50% people agree that the motivation for exercise is to lose weight. Through analyzing the characteristic of sports, the results show that more than 75% students are willing to carry out sports with friends, however, due to the lack of places to participate in sports activities, most of the students chose the school or district park for physical exercise. So that, physical education in colleges should pay attention to the cultivation of sports habits, improve students' enthusiasm for physical exercise. © 2016 SERSC.


Reported here are two new Cd(II) coordination polymers, namely [Cd2(L)2]n·n(H2O) (1) and [Cd2(L)(4,4-bipy)0.5]n(2) (H2L = 5-(pyridin-2-ylmethoxy)-isophthalic acid, 4,4,-bipy = 4,4′-bipyridine), which were successfully synthesized via the hydrothermal reactions of Cd(NO3)2and H2L or Cd(NO3)2, 4,4-bpy and H2L. Compound 1 is a 2D layer structure with (3,6)-connected kgd topology, while compound 2 is a 3D pillar-layered framework with (3,4,4)-connected topology. Additionally, the thermal stabilities and luminescent properties of these two compounds were also investigated. © 2014 Elsevier B.V.


Zhang G.-H.,Shaanxi University of Chinese Medicine
Journal of Thermal Analysis and Calorimetry | Year: 2016

Two pure microporous materials for copper borophosphates, Cu(H2O)2[B2P2O8(OH)2] and Cu3[B2P3O12(OH)3], have been synthesized and characterized by XRD, FTIR, simultaneous TG–DTA and chemical analysis. The molar enthalpies of solution of Cu(H2O)2[B2P2O8(OH)2] (s) and Cu3[B2P3O12(OH)3] (s) in 3 mol dm−3 HCl (aq) were measured, respectively. The molar enthalpies of solution of CuCl2·2H2O (s) in the mixture solvent of (HCl + H3BO3) (aq), and of H3PO4 (s) in the mixture solvent of (HCl + H3BO3 + CuCl2·2H2O) (aq) were also measured. With the incorporation of the previously determined enthalpy of solution of H3BO3 (s) in 3 mol dm−3 HCl (aq), together with the standard molar enthalpies of formation for H3PO4 (s), CuCl2·2H2O (s), H3BO3 (s), HCl (aq) and H2O (l), the standard molar enthalpies of formation of −(4078.8 ± 1.7) kJ mol−1 for Cu(H2O)2[B2P2O8(OH)2] (s) and −(4805.7 ± 2.0) kJ mol−1 for Cu3[B2P3O12(OH)3] (s) at 298.15 K were obtained on the basis of the appropriate thermochemical cycles. © 2016 Akadémiai Kiadó, Budapest, Hungary


Pei K.,Shaanxi University of Chinese Medicine
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials | Year: 2012

To analysis liposoluble constituents of Holotrichia diomphalia by GC-MS and measure their anti-inflammatory and analgesic activities. The composition of liposoluble constituents were determined by GC-MS. The dimethylbenzene-induced mice inflammatory models were established. The pain models were obtained by hot plate and acetic acid in mice. Twenty-two components were identified from the petroleum ether extract of Holotrichia diomphalia. The major components were oleic acid, palmitic acid and palmitoleic acid. The petroleum ether extract was able to significantly inhibit the mice ear edema induced by dimethyl-benzene. The pain in mice caused by acetic acid and hot plate were evidently suppressed by the petroleum ether extract. The petroleum ether extract of Holotrichia diomphalia has obvious anti-inflammation and analgesic effects.


Fan Y.,Shaanxi University of Chinese Medicine
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials | Year: 2013

To investigate the effect of total saponin of Aralia Taibaiensis on the leukemia cells and explore the mechanisms of early apoptosis. The leukemia cells lines K562 and U937 were cultured in vitro and divided into 2 groups: control group and treatment group. The proliferation inhibition of leukemia cells was measured by MTT assay. K562 cells morphological changes were observed under the reverse microscope; Flow cytometry (FCM) was used to detect the influence of total saponin of Aralia Taibaiensis on changes of mitochondrial membrane potential in K562 cells. The expression of protein BCL-2 and BAX in K562 cells was investigated by immunohistochemistry. The total saponin of Aralia Taibaiensis had significant inhibitory effects on K562 and U937 cell lines, and the inhibitory effects on these two cells lines presented time-dependent and dose-dependent manner. The results by inverted microscope were consistent with that of the MTT assay. FCM analysis showed that total saponin of Aralia Taibaiensis could induce mitochondrial membrane potential of K562 cells. Compared with control group, the expression of BCL-2 in treatment group was down-regulated, the expression of BAX was significantly up-regulated. The total saponin of Aralia Taibaiensis can inhibit two kinds of leukemia cells lines in vitro, and the mechanism may be related to promoting the early apoptosis of K562 cells.

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