Dehradun, India


Dehradun, India

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Kumar L.,Health-U | Agarwal S.,Saraswathi Institute of Medical science | Garg R.,SGRRIM and HS | Pratap A.,SGRRIM and HS | Mishra,SGRRIM and HS
Journal of Indian Academy of Forensic Medicine | Year: 2013

This study was conducted with an aim to establish a relationship between sex and fingerprint ridge density in Uttarakhand. The fingerprints were taken from 250 subjects (125 males and 125 females) in the age group of 18-60 years. After taking fingerprints, the ridges were counted in the upper portion of the radial border of each print for all ten fingers, and mean value was calculated. The results have shown that a finger print ridge of < 12 ridges/25 mm2 are more likely of male origin and finger print ridge of > 14 ridges/25 mm2 are more likely of female origin. The study suggests that there are significant differences in epidermal ridge density between males and females and also support the hypothesis that women tend to have a statistically significant greater ridge density than men. This study will provide additional information for the fingerprint examiners in analyzing finger impressions and narrowing down an investigation involving a large number of samples.

Thakur B.,SGRRIM and HS | Varma K.,Mlnmedical College | Misra V.,Mlnmedical College | Chauhan S.,CGHS
Journal of Clinical and Diagnostic Research | Year: 2013

Granulocytic sarcoma is a rare variant of a myeloid malignancy, which shows an extra-medullary tumour mass which is composed of myeloblasts and myeloid precursors with varying degrees of differentiation. It occurs most commonly in bone, periosteum, soft tissue, lymph nodes, and skin; although it can occur anywhere throughout the body. Here, we are reporting two cases of orbital granulocytic sarcoma in children, which presented clinically with proptosis and periorbital swellings, which were first diagnosed by Fine Needle Aspiration Cytology (FNAC). Later, peripheral blood and bone marrow aspirate examinations revealed the evidence of Acute Myeloid Leukaemia (AML). These cases are being documented to demonstrate the utility and diagnostic accuracy of FNAC in evaluation of this entity, in cases of unsuspected AML. Recognition of this rare entity is important, because giving an early aggressive chemotherapy can cause regression of the tumour and thus improve the patient survival.

Devi S.,SGRRIM and HS | Saxena J.,G.S.V.M.M.C | Rastogi D.,G.S.V.M.M.C | Goel A.,AIIMS | Saha S.,G.S.V.M.M.C
Indian Journal of Physiology and Pharmacology | Year: 2014

The effect of short term (12 weeks) physical exercise on serum total testosterone level was evaluated in 30 young male adults, aged 18-27 years (mean age 21.67±2.26 years). These medical students, having sedentary life style underwent heavy exercise by attaining heart rate 125-150 beats/min on bicycle ergometer for 15 min on alternate day basis amounted to 670 kilopond metre per minute work done and percentage of VO2max was 71±3. Pre-exercise serum total testosterone levels (5.49±1.31) of students were compared with those obtained after 1 week and 12 weeks of initiation of exercise. The serum total testosterone was measured by DRG Testosterone ELISA kit. After 1 week of exercise, a statistically insignificant decrease (5.488±1.32; P>0.05) was found while after 12 weeks of exercise, a statistically significant increase (6.41±2.28 P<0.05) was noticed between the pre-and post-exercise serum total testosterone levels. We conclude that short-term exercise produces an elevation in serum testosterone levels in young adults.

Luthra M.,SGRRIM and HS | Luthra S.,Drishti Eye Institute | Negi K.S.,SGRRIM and HS
Indian Journal of Community Health | Year: 2014

Introduction: Age-related macular degeneration (AMD) is among the fourth leading cause of blindness in India after cataract, refractive errors and glaucoma. Aim and Objective: To find out magnitude and determinants of blinding AMD among patients presenting at a tertiary level eye care centre in Dehradun with this condition. Material and methods: This was a study of eye patients above age 45 years seen from July 2010 to October 2013. After taking preliminary information, optometrist noted the best-corrected vision. Ophthalmologists examined eyes using a slit-lamp bio-microscope. AMD was confirmed by fluorescein angiography and optical coherence tomography. The age, sex, history of smoking, sun exposure, family history of AMD, diet, body mass index (BMI), history of hypertension, dyslipidemia and diabetes were noted. Results: Of the 14,698 patients seen, 221 had AMD (dry or wet) in at least one eye, the overall proportion of AMD being 1.50%. Of all AMD patients, 103 had blinding wet AMD (46.61%).Further analysis revealed that old age (71-80 years), male sex and history of hypertension, diabetes etc were significant risk factors of wet AMD. Of the 221 patients with AMD, nearly a third, that is 71 patients (32.13%) had visual acuity of better eye < 3/60, which was taken as criteria for blindness. Conclusions: AMD does not seem to be a problem of public health magnitude in the study area. Age, being male, history of hypertension, diabetes etc are significant risk factors for wet AMD. © 2014, INDIAN JOURNAL OF COMMUNITY HEALTH. All rights reserved.

Mongia S.M.,SGRRIM and HS | Jain S.K.,SGRRIM and HS | Yadav M.,Sharda University
Journal of Indian Academy of Forensic Medicine | Year: 2011

Placenta is the only organ to develop in adulthood and is the only one with a defined end date. The structure of placenta has a strong relation with pregnancy length, physical milieu of mother and a resemblance to the concept of 'Imhotep(regarded as the first medico legal expert) showing relation between Forensic medicine histology, morphology and pathology. Anemia in pregnancy is found to be associated with variable histomorphological changes in placenta, which show a clear reflection for the poor fetal outcome. There is a threshold for the level of haemoglobin and consequently for oxygen transport below which placental function is impaired. This explains the increased frequency of premature births, foetal death and perinatal mortality and morbidity in anemia during pregnancy. The histomorphological findings of placenta in anemic mothers which are an adaptation to maternal hypoxia can correlate with the poor fetal outcome giving a documentary evidence and explanation against false implications of neonatal deaths. This makes placenta as the much required tool of present medico legal scenario.

Anjum B.,University of Lucknow | Verma N.S.,University of Lucknow | Tiwari S.,University of Lucknow | Singh R.,University of Lucknow | And 3 more authors.
BioScience Trends | Year: 2011

Recent studies indicate a circadian rhythm in blood pressure and heart rate and its association with various neurotransmitters. In the present study, we examine the circadian nature of blood pressure/heart rate and salivary cortisol in night shift workers and whether these circadian changes produced by night shifts are reversible. Sixteen healthy nurses of both genders, aged 20-40 years, performing day and night shift duties, were randomly selected out of 22 who volunteered for this study. Ambulatory blood pressure monitoring was done in all the subjects and salivary cortisol levels were analyzed during both day and night shift duties. There were clinically significant changes in the Acrophase of blood pressure and cortisol levels, indicating ecphasia (odd timing of systolic blood pressure) individually during night as well as day shifts. However, this pattern was statistically not significant. A reverse pattern of Acrophase was observed in 8 out of 16 subjects when they were posted on day shift. No significant change was found in midline estimating statistics of rhythm (MESOR) of blood pressure values. Changes in Double amplitude (Predictable change) were observed in 8 subjects during night shifts as well as in 7 subjects during day shifts. However, the pattern was not similar and night workers had an altered circadian pattern in the night as well as during day shifts. Changes in Double amplitude, Acrophase and Salivary cortisol were found during night as well as day shifts but these changes were not statistically significant (p > 0.05) due to incomplete recovery during day shifts (changes again seen when they came back to day shifts). Salivary cortisol levels were lowest in early morning, increased at midnight and further increased in the afternoon during night shifts along with ecphasia. It is possible that nurses working the night shift felt more tired due to the altered circadian cycle.

Raina D.,SGRRIM and HS | Gupta P.,All India Institute of Medical Sciences | Khanduri A.,SGRRIM and HS
Annals of Tropical Medicine and Public Health | Year: 2016

This is the first case of Microsporum ferrugineum isolated from a patient in Uttarakhand. A 56-year-old man came to the skin outpatient department with the chief complaints of tinea corporis associated with the symptoms of tinea cruris. Examination of the patient disclosed diffuse erythematic and perifollicular papules and pustules in the chest, abdominal, and the back. Typical vesiculopustular lesions involved the skin of groin area also. Isolate was identified as M. ferrugineum on the basis of macroscopic and microscopic colony characteristics. The patient was treated successfully with griseofulvin which was administered for 4 weeks. © 2016 Annals of Tropical Medicine and Public Health Published by Wolters Kluwer - Medknow.

Dixit S.P.,SGRRIM and HS | Bansal R.K.,SGRRIM and HS
Journal of Indian Academy of Forensic Medicine | Year: 2014

Age estimation in the living is one of the most important tasks of a Forensic practitioner especially in developing countries where birth records are often not well-maintained. The age between 15 to 17 years is very important medico-legally especially in the females, it is important to differentiate between 14-15 yrs in employment and 17 to 18 in connection with Hindu marriage Act. X-ray study of epiphysis of bones has traditionally been used for age estimation by observing the ossification centers. On the other hand, Ultrasonography is a much safer, effective and non invasive procedure. The study was carried out between 2011 and 2014 on 100 female patients of Garhwali origin. The age of the subjects was from 15 to 17 years which was verified from date of birth certificate. The main focus of the present study was to find out the age of fusion of ossification centers in the upper ends of radius&ulna, and lower end of humerus. In order to narrow down the range of age an attempt has been made to undertake this study by means of Ultrasonography. During the study, encouraging results were discovered.

Kishore S.,SGRRIM and HS | Thakur B.,SGRRIM and HS | Azad S.,SGRRIM and HS | Kudesia S.,SGRRIM and HS
Indian Journal of Pathology and Microbiology | Year: 2016

Soft tissue chondroma is a rare benign, slow growing tumor usually located in hand and foot. Scrotal chondroma is exceedingly rare; chondromas in the pelvic region have also been reported. However, chondroma occurring in the scrotal wall is extremely rare, and only a few cases have been reported worldwide. They should be differentiated from well-differentiated chondrosarcoma. To the best of our knowledge, this is the first case of scrotal chondroma to be reported from India. © 2016 Indian Journal of Pathology and Microbiology | Published by Wolters Kluwer - Medknow.

PubMed | SGRRIM and HS
Type: Case Reports | Journal: Indian journal of pathology & microbiology | Year: 2016

Soft tissue chondroma is a rare benign, slow growing tumor usually located in hand and foot. Scrotal chondroma is exceedingly rare; chondromas in the pelvic region have also been reported. However, chondroma occurring in the scrotal wall is extremely rare, and only a few cases have been reported worldwide. They should be differentiated from well-differentiated chondrosarcoma. To the best of our knowledge, this is the first case of scrotal chondroma to be reported from India.

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