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Rao K.,SGRD Institute of Medical science and Research | Kumar S.,Institute of Dental science
Indian Journal of Otolaryngology and Head and Neck Surgery | Year: 2014

The purpose of this study was to evaluate the use of enucleation and chemical cauterization in the management of odontogenic keratocyst (OKC) of the jaw. This study involves the retrospective review of 32 patients (20 males and 12 females) with 34 biopsy proven odontogenic keratocysts. All patients received a combination of enucleation and chemical cauterization with every time freshly prepared Carnoy's solution (absolute alcohol 6 mL, chloroform 3 mL, glacial acetic acid 1 mL, ferric chloride 0.1 gm/mL). None of these patients were diagnosed with basal cell nevus syndrome. Four of these patients did not give the follow up and were not included in the study. A total of 30 biopsy proven OKC were resolved with this treatment method. Post-operative follow up consists of clinical and radiographic examination. Follow up time ranged from a minimum of 2 years to a maximum of 5 years. Mean follow up was of 2.8 years. Recurrence rate of 5.8% was observed. Hence, concluded that the combination of enucleation and chemical cauterization may offer patients improved therapy in the management of odontogenic keratocysts of the jaws. © 2012 Association of Otolaryngologists of India. Source

Natt N.K.,Government Medical College | Tarsem S.,SGRD Institute of Medical science and Research | Anubha,SGRD Vallah | Simarjeet S.,SGRD Vallah | And 2 more authors.
Journal of Nepal Paediatric Society | Year: 2015

Drug reaction with eosinophilia and systemic symptoms (DRESS) is a rare and potentially fatal adverse effect characterized by a skin rash with visceral involvement and haematological abnormalities. This adverse drug effect is often misdiagnosed and under-reported especially in paediatric age group due to its rarity and high occurrence of skin rash in various other viral illnesses of children. We report a case of DRESS in a three months old male child. A high index of suspicion, rapid diagnosis and prompt withdrawal can be life-saving for the patient. © 2015, Nepal Paediatric Society (NEPAS). All rights reserved. Source

Kiran Rao,SGRD Institute of Medical science and Research | Sudesh Kumar,Institute of Dental science
Gujarat Journal of Otorhinolaryngology and Head and Neck Surgery | Year: 2012

Nasorespiratory function and its relation to craniofacial growth is of great practical concern. Adenoid hypertrophy can cause nasal obstruction leading to mouth breathing which in turn cause a narrow maxillary dental arch and a high arched palate. There is a striking lack of scientific studies which make critical evaluation of this hypothesis difficult. Having the opinion of both dental surgeon and otorhinolaryingologist, we can see the strength of argument that adenoid obstruction can affect dentofacial structure. Here we present the study of 60 cases of adenoid hypertrophy. The aim of this study is to reveal both passionate support of and opposition to the hypothesis. Source

Batra A.P.S.,SGRD Institute of Medical science and Research | Mahajan A.,SGRD Institute of Medical science and Research | Gupta K.,Chakitsa Hospital
Indian Journal of Plastic Surgery | Year: 2010

Smile is one of the most natural and important expressions of human emotion. Man uses his lips mainly to register his emotions. Thus, the slightest asymmetry or weakness around the lips and mouth may transform this pleasant expression into embarrassment and distortion. The circumoral musculature, the major part of which is supplied by the marginal mandibular branch of the facial nerve, is the main factor in this expression. Therefore, an injury to this nerve during a surgical procedure can distort the expression of the smile as well as other facial expressions. This nerve often gets injured by surgeons in operative procedures in the submandibular region, like excision of the submandibular gland due to lack of accurate knowledge of variations in the course, branches and relations. In the present study, 50 facial halves were dissected to study the origin, entire course, termination, branches, muscles supplied by it, its anastomoses with other branches of facial nerve on the same as well as on the opposite side and its relations with the surrounding structures. The marginal mandibular branch of the facial nerve was found superficial to the facial artery and (anterior) facial vein in all the cases (100%). Thus the facial artery can be used as an important landmark in locating the marginal mandibular nerve during surgical procedures. Such a study can help in planning precise and accurate incisions and in preventing the unrecognized severance of this nerve during surgical procedures. Source

Natt N.K.,SGRD Institute of Medical science and Research | Gupta A.,Government of Punjab | Singh G.,Government of Punjab | Singh T.,SGRD Institute of Medical science and Research
Indian Journal of Ophthalmology | Year: 2014

Aims: The aim was to compare efficacy and cost-effectiveness of bimatoprost 0.03% and brimonidine 0.2% in primary open-angle glaucoma (POAG)/ocular hypertension (OHT). Settings and Design: Open, randomized, cross-over, comparative study. Materials and Methods: Forty patients of POAG or OHT with intraocular pressure (IOP) <30 mm Hg were included in the study after a written informed consent. The patients were divided randomly into two groups of 20 patients each. Patients of group A were administered bimatoprost 0.03% eye drops once daily, and those of group B brimonidine 0.2% eye drops twice daily for a period of 4 weeks. After a washout period of 4 weeks, the patients were crossed over that is, group A was administered brimonidine 0.2% and group B bimatoprost 0.03%. Fall in IOP at 4 weeks was recorded. The daily cost of each drug was calculated by maximum retail price and the average number of drops per bottle. The cost-effectiveness was then calculated as the cost of drug/mm Hg fall in IOP. Statistics: Independent samples t-test was used to compare the efficacy of both drugs. Results: IOP lowering with bimatoprost (8.9 ± 1.598 mm Hg) was significantly (P < 0.0001) higher than brimonidine (6.55 ± 1.26 mm Hg). The number of drops/ml were 33.43 ± 0.52 and 25.49 ± 0.26, respectively, for bimatoprost and brimonidine. Treatment with bimatoprost was costlier than brimonidine with daily costs/eye Rs. 4.02 ± 0.06 and 3.14 ± 0.03, yearly costs/eye Rs. 1467.46 ± 20.74 and 1147.75 ± 11.15, respectively. Bimatoprost was more cost-effective than brimonidine with the cost-effectiveness ratio (CER) respectively Rs. 13.10 ± 2.61/mm Hg and Rs. 13.96 ± 2.86/mm Hg. Incremental CER Rs. 10.43/mm Hg implies lower costs/mm Hg extra IOP lowering by bimatoprost than Rs. 13.96 for brimonidine. Conclusion: In spite of being costlier, bimatoprost is more efficacious and cost-effective than brimonidine. Source

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