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Zetu C.,Institute of Diabetes | Zetu C.,Carol Davila University of Medicine and Pharmacy | Munteanu R.,Emergency Clinical Hospital Sf. Ioan | Parasca R.,Clinical Hospital Regina Maria | Ionescu-Tirgoviste C.,Institute of Diabetes
Romanian Journal of Diabetes, Nutrition and Metabolic Diseases | Year: 2013

Obesity is an epidemic disease, increasingly addressed through surgical options for weight loss. Benefits of these surgical procedures, such as weight loss and improvement of obesity-related co-morbidities, are well established. However, postoperative complications do occur. Deficiencies in micronutrients, which include water and fat-soluble vitamins and minerals, are common after bariatric surgery. Recognition of the clinical signs and symptoms of micronutrient deficiencies is important to minimize long-term adverse effects. © 2013 ILEX PUBLISHING HOUSE.


Zetu C.,Institute of Diabetes | Zetu C.,Carol Davila University of Medicine and Pharmacy | Munteanu R.,Emergency Clinical Hospital Sf. Ioan | Frunza A.,Institute of Diabetes | Ionescu-Tirgoviste C.,Institute of Diabetes
Romanian Journal of Diabetes, Nutrition and Metabolic Diseases | Year: 2012

The prevalence of type 2 diabetes mellitus (T2DM) and obesity is steadily increasing worldwide. To fight the twin pandemics of obesity and T2DM, clinicians need every tool they can get. Major, durable weight loss is uncommon with medical and behavioral approaches; many diabetes drugs promote weight gain, while using them to obtain better blood glucose profiles increases the risk of hypoglycemia. Bariatric surgery seems to be the most effective method for promoting major and durable weight loss in obese subjects, leading also to ameliorations of obesity-associated comorbidities, especially T2DM. Currently, indications for bariatric surgery include morbidly obese patients or patients with a body mass index (BMI) >35 with significant co-morbidities. Currently, bariatric surgery (also referred to as "metabolic surgery") is advocated for the treatment of T2DM even in overweight subjects who do not meet the current BMI criteria. This review examines the current evidence regarding the mechanisms of T2DM resolution following bariatric surgery. © 2012 ILEX PUBLISHING HOUSE, Bucharest, Roumania.

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