Caracas, Venezuela
Caracas, Venezuela

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Munoz J.S.,Cardiovascular Research Center Caracas | Sanchez O.,Instituto Medico La Floresta | Correa R.,Centro Medico Of Caracas | Aguiar P.,Instituto Medico La Floresta | And 9 more authors.
Revista Brasileira de Cardiologia Invasiva | Year: 2013

Background: Systemic arterial hypertension affects over 1.2 million people worldwide. Only 35% of hypertensive patients have controlled blood pressure levels. Renal sympathetic denervation (RSD) has shown to significantly decrease blood pressure levels in patients with resistant systemic hypertension. Methods: Prospective, single arm, observational, multicenter study including consecutive patients undergoing RSD. The primary endpoint was to assess systolic blood pressure levels at the 30-day follow-up. The secondary endpoint was to determine the presence of procedure-related adverse events. Results: The first 20 patients undergoing RSD were included. The average blood pressure prior the procedure was 171.6/93.2 + 15.5/ 11.3 mmHg, with the use of 4.1 + 1.5 antihypertensive drugs per patient. Success rate was 95%, and 11.1 + 1.9 ablations were performed per patient. A systolic blood pressure decrease of 29 + 21 mmHg (P = 0.009) was observed 30 days after the procedure. There were no procedure-related complications. Conclusions: Catheter-based RSD in daily clinical practice patients significantly decreased blood pressure levels. In our experience, RSD proved to be feasible and safe.

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