Servicios de Salud de Morelos

Ecatepec, Mexico

Servicios de Salud de Morelos

Ecatepec, Mexico
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Burgos-Vargas R.,Hospital General Of Mexico | Cardiel M.,Research Center Clinica Of Morelia | Xibille D.,Servicios de Salud de Morelos | Pacheco-Tena C.,Autonomous University of Chihuahua | And 7 more authors.
Reumatologia Clinica | Year: 2016

Objectives: Tofacitinib is an oral Janus kinase inhibitor for the treatment of rheumatoid arthritis (RA). We characterized efficacy and safety of tofacitinib in Mexican patients from RA Phase 3 and long-term extension (LTE) studies. Methods: Data from Mexican patients with RA and an inadequate response to disease-modifying antirheumatic drugs (DMARDs) were taken from four Phase 3 studies (pooled across studies) and one open-label LTE study of tofacitinib. Patients received tofacitinib 5 or 10. mg twice daily, adalimumab (one Phase 3 study) or placebo (four Phase 3 studies) as monotherapy or in combination with conventional synthetic DMARDs. Efficacy up to Month 12 (Phase 3) and Month 36 (LTE) was assessed by American College of Rheumatology 20/50/70 response rates, Disease Activity Score (erythrocyte sedimentation rate), and Health Assessment Questionnaire-Disability Index. Safety, including incidence rates (IRs; patients with events/100 patient-years) for adverse events (AEs) of special interest, was assessed throughout the studies. Results: 119 and 212 Mexican patients were included in the Phase 3 and LTE analyses, respectively. Tofacitinib-treated patients in Phase 3 had numerically greater improvements in efficacy responses versus placebo at Month 3. Efficacy was sustained in Phase 3 and LTE studies. IRs for AEs of special interest were similar to those with tofacitinib in the global and Latin American RA populations. Conclusions: In Mexican patients from the tofacitinib global RA program, tofacitinib efficacy was demonstrated up to Month 12 in Phase 3 studies and Month 36 in the LTE study, with a safety profile consistent with tofacitinib global population. © 2017 Elsevier España, S.L.U. and Sociedad Española de Reumatología y Colegio Mexicano de Reumatología.


Tellez-Rojo M.M.,Instituto Nacional Of Salud Publica | Bautista-Arredondo L.F.,Instituto Nacional Of Salud Publica | Richardson V.,Secretaria de Salud de Morelos | Estrada-Sanchez D.,Pure Earth | And 11 more authors.
Salud Publica de Mexico | Year: 2017

Objective. To determine the prevalence of lead (Pb) poisoning at birth in Morelos, analyze its distribution by social marginalization level, and estimate the association with the use of lead glazed ceramics (LGC). Materials and methods. Blood lead level (BLL) in umbilical cord was measured in a representative sample of 300 randomly selected births at the Morelos Health Services and state IMSS. Results. The prevalence of Pb poisoning at birth (BLL > 5μg/dL) was 14.7% (95%CI: 11.1, 19.3) and 22.2% (95%CI: 14.4, 32.5) in the most socially marginalized municipalities. 57.1% (95%CI: 51.3, 62.7) of the mothers used LGC during pregnancy, and the frequency of use was significantly associated with BLL. Conclusion. This is the first study to document the proportion of newborns with Pb poisoning who are at risk of experiencing therelated adverse effects. It is recommended to monitor BLL at birth and take action to reduce this exposure, especially in socially marginalized populations.


Cuadra-Hernandez S.M.,Research Center En Sistemas Of Salud | Bernabe-Aranda J.L.,Servicios de Salud de Morelos | Conde-Glez C.J.,Research Center en Salud Poblacional | Sanchez-Dominguez M.S.,Research Center En Sistemas Of Salud | Ortega-Altamirano D.V.,Research Center En Sistemas Of Salud
Salud Publica de Mexico | Year: 2015

Objective. In 2009, 4 749 rapid HIV tests were run in Morelos, Mexico, despite lacking evidence on their results. This article seeks to analyze how public health organization relates to utility of rapid HIV test among healthcare users. Materials and methods. Joint study: comparison of differences in applied test and positive results for each group with the Bonferroni statistical tool, observational study in 34 health subsystems, and 11 interviews with public healthcare users. Results. Each subsystem processes influenced the use and usefulness of screening; for instance, primary care centers test only pregnant women and exclude men who have sex with men (MSM). That group shows significant differences (p < 0.007) in the HIV-positive test with respect to other groups. Conclusions. Despite the availability of rapid detection tests and epidemiological evidence, the way public health services are organized impedes an efficient diagnosis in the group with higher risk, namely MSM. The distribution of rapid HIV tests was guided by stigmatization.


Villegas-Trejo A.,Servicios de Salud de Morelos | Manrique-Saide P.,University Autnoma Of Yucatn | Che-Mendoza A.,Servicios Estatales de Salud de Guerrero | Cruz-Canto W.,University Autnoma Of Yucatn | And 5 more authors.
Journal of the American Mosquito Control Association | Year: 2010

Aedes albopictus, Culex corniger, Cx. restuans, and Toxorhynchites theobaldi are reported for the first time for the Mexican State of Morelos. The updated list of species reported is also presented. © 2010 by The American Mosquito Control Association, Inc.


Villegas-Trejo A.,Servicios de Salud de Morelos | Che-Mendoza A.,Servicios de Salud de Morelos | Gonzalez-Fernandez M.,Servicios de Salud de Morelos | Guillermo-May G.,Autonomous University of Yucatán | And 5 more authors.
Salud Publica de Mexico | Year: 2011

Objective: To determine the relative importance of Aedes aegyti breeding sites for potential targeted dengue control interventions in Morelos. Material and Methods: Cross-sectional entomological surveys were conducted and collection of Ae. aegypti pupae was taken from all water-holding containers in Cuautla, Jojutla and Tlaquiltenango during dry (1 713 households) and rainy (1 677) seasons in 2008. Relative importance of different types of breeding sites was determined by the contribution (%) to total pupae production within each locality. Results: In Cuautla most pupae during the dry season were found in wash basins (48.5%), tanks and buckets/pots (15% each); during the rainy season, diverse small items (21.3%), buckets/pots (19.3%) and plant pots (12.9%) were more productive. In Jojutla and Tlaquiltenango, 97% of all pupae was found in plant pots during the dry season; during the rainy season diverse small items (26.3%), washing/cooking utensils (13.9%), buckets/pots (12.9%) and plant pots (12.7%) were significant. Conclusion: Prevention and control of the dengue vector should be based on this kind of evidence to target the most productive breeding-sites.


Canedo-Dorantes L.,Autonomous University of Morelos | Soenksen L.R.,Monterrey Institute of Technology | Garcia-Sanchez C.,Autonomous University of Morelos | Trejo-Nunez D.,Autonomous University of Morelos | And 9 more authors.
Archives of Medical Research | Year: 2015

Background and Aims: Cellular and animal models investigating extremely low frequency magnetic fields (ELF-MF) have reported promotion of leukocyte-endothelial interactions, angiogenesis, myofibroblast and keratinocyte proliferation, improvement of peripheral neuropathy and diabetic wound healing. In humans, it has also been reported that systemic exposure to ELF-MF stimulates peripheral blood mononuclear cells, promoting angiogenesis and healing of chronic leg ulcers. The aim of the study was to investigate the effect of exposing different blood volumes to specific ELF-MFs (120 Hz sinusoidal waves of 0.4-0.9 mT RMS) to induce healing of diabetic foot ulcers (DFUs). Methods: Twenty six diabetic patients with non-responsive DFUs were divided into two exposure groups to receive treatment and record healing time. The forearm group, exposed to ELF-MF 2 h/day, twice weekly (3.6 l of blood/session); and the thorax group, exposed 25 min/day, 2 times/week (162.5 l of blood/session). Treatment period was 100 days or upon complete healing. Ulcer recurrences and adverse effects were investigated during short-term (<1 year) and long-term (3.4-7.8 years) follow-up. Results: Mean healing time was 61.48 ± 33.08 days in the forearm group and 62.56 ± 29.33 days for the thorax group. No adverse effects or ulcer recurrences in the original ulcer site were reported during treatment, the short-term follow-up period or the long-term follow-up period in both groups. Conclusions: Healing time was independent of the amount of blood exposed to ELF-MF used in this trial. ELF-MFs are effective and safe and could be applied to non-healing DFUs in conjunction with other preventive interventions to reduce DFUs complications. © 2015 IMSS.


PubMed | Servicios de Salud de Morelos
Type: Journal Article | Journal: Revista de saude publica | Year: 2010

To analyze municipal measures implemented to control the dengue epidemic, giving priority to the functions of intersectoral coordination, policy strengthening and community participation.The observational study was performed in Morelos, Mexico in 2007. Data collected in interviews and direct observations were submitted to contents analysis and policy mapping. Policy Maker software was used to evaluate the values assigned to the stakeholders performance (i.e., high, medium and low criteria) and to their role (actions undertaken for surveillance, control or management). A strategic analysis of opportunities and challenges regarding public policies and dengue control was conducted.The legal framework indicates that the approach to the dengue epidemic should be an intersectoral response. However, the burden of activities in terms of financial and human resources tends to fall on local health services, which contrasts with the contribution of other sectors (e.g., water and sanitation) that do not recognize their responsibilities. A high degree of operational feasibility links, in terms of optimization of resources and objectives fulfillment was detected, particularly among health authorities at state, jurisdictional and municipal levels.A multidisciplinary approach and strengthening of policy stewardship may allow a more efficient response to dengue outbreaks, sustained by intersectoral coordination and the active participation of the affected population.


PubMed | Servicios de Salud de Morelos
Type: Journal Article | Journal: Journal of the American Mosquito Control Association | Year: 2010

Aedes albopictus, Culex corniger, Cx. restuans, and Toxorhynchites theobaldi are reported for the first time for the Mexican State of Morelos. The updated list of species reported is also presented.

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