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Hospital de Órbigo, Spain

Carrera-Martinez D.,Centro Polivalente Of Recursos Clara Ferrer | Avanzas-Fernandez S.,Servicio de Medicina Interna | Gracia-Corbato M.,Servicio Of Laboratorio Clinico
Revista de Calidad Asistencial | Year: 2012

Objectives: Evaluate the level of satisfaction in the Medical Oncology Services in our Community of women with breast cancer, and analyse the influence of sociodemographic and clinical factors on their satisfaction. Material and methods: Cross-sectional multicentre study using an anonymous and voluntary questionnaire completed by 225 women diagnosed with breast cancer. The tool used was the modified SERVQHOS, adapted to our context. We collected demographic and clinical data. To determine the reliability of the tool after the adjustments, a Cronbach's alpha analysis was performed. A descriptive analysis was also performed, as well as non-parametric statistics to study the influence of demographic variables on satisfaction. Results: The best evaluated aspects were the kindness of the staff [4.30 ± 0.83 (2-5)], the confidence transmitted by them [4.23 ± 0.79 (2-5)] and personal treatment [4.12 ± 0.88 (2-5)]. The worst evaluated was the ease of getting to the hospital [3.06 ± 0.99 (1-5)], waiting time [3.16 ± 1.00 (1-5)], state of consultations rooms [3.38 ± 0.99 (1-5)] and punctuality of the sessions [3.38 ± 1.05 (1-5)]. The overall satisfaction was 4.04 ± 0.82 (1-5). Age influenced their assessment of the personal appearance of the staff (P =.04), the state of consultations rooms (P < 00), the ease of getting to the hospital, and the quantity and quality of information received (P = 01). Educational level influenced their satisfaction with personal appearance of the staff (P =03) and the state of consultations rooms (P = 03). Women who worked and those who were temporary disabled women evaluated the appearance of personnel worst (P = 02). The time from the diagnosis affected the satisfaction with the staff willingness to help (P < 00) and therapy attendance, and the satisfaction with the ability to understand their needs (P = 03). Conclusions: The individual characteristics of the participants influence their satisfaction. We have been able to identify deficient areas from their point of view, identifying important improvement opportunities in several aspects of care to work on in order to increase the quality of care. © 2011 SECA. Published by Elsevier España, S.L. All rights reserved.

Moreno-Luna R.,University of Seville | Munoz-Hernandez R.,University of Seville | Miranda M.L.,University of Seville | Costa A.F.,University of Seville | And 5 more authors.
American Journal of Hypertension | Year: 2012

Background Olive oil polyphenols have been associated with several cardiovascular health benefits. This study aims to examine the influence of a polyphenol-rich olive oil on blood pressure (BP) and endothelial function in 24 young women with high-normal BP or stage 1 essential hypertension.MethodsWe conducted a double-blind, randomized, crossover dietary-intervention study. After a run-in period of 4 months (baseline values), two diets were used, one with polyphenol-rich olive oil (∼30 mg/day), the other with polyphenol-free olive oil. Each dietary period lasted 2 months with a 4-week washout between diets. Systolic and diastolic BP, serum or plasma biomarkers of endothelial function, oxidative stress, and inflammation, and ischemia-induced hyperemia in the forearm were measured.ResultsWhen compared to baseline values, only the polyphenol-rich olive oil diet led to a significant (P < 0.01) decrease of 7.91 mm Hg in systolic and 6.65 mm Hg of diastolic BP. A similar finding was found for serum asymmetric dimethylarginine (ADMA) (-0.09 ± 0.01 ̄mol/l, P < 0.01), oxidized low-density lipoprotein (ox-LDL) (-28.2 ± 28.5 ̄g/l, P < 0.01), and plasma C-reactive protein (CRP) (-1.9 ± 1.3 mg/l, P < 0.001). The polyphenol-rich olive oil diet also elicited an increase in plasma nitrites/nitrates (+4.7 ± 6.6 ̄mol/l, P < 0.001) and hyperemic area after ischemia (+345 ± 386 perfusion units (PU)/sec, P < 0.001).ConclusionsWe concluded that the consumption of a diet containing polyphenol-rich olive oil can decrease BP and improve endothelial function in young women with high-normal BP or stage 1 essential hypertension. © 2012 American Journal of Hypertension, Ltd.

Jans B. J.,Servicio de Cirugia | Jans B. J.,Austral University of Chile | Talma R. M.J.,Austral University of Chile | Almonacid R. M.,Austral University of Chile | And 6 more authors.
Revista Chilena de Cirugia | Year: 2013

Introduction: CA 19-9 has been identified as a derivative of sialic Lewis blood group A and is expressed in 95% of the population. Several studies have documented an overproduction of CA 19-9 in malignant pancreatic and biliary tree diseases. The objective of this study is to determine the accuracy of the tumor marker CA 19-9 differentiating benign and malignant bilio-pancreatic diseases. Material and Methods: Diagnostic test study. We reviewed the records of all patients with malignant bilio-pancreatic diseases and benign biliary calculous diseases evaluated in Hospital Base Osorno between August 2007 and December 2011, with CA 19-9 as part of their study. Results: 71 patients met the inclusion criteria, 17 men and 54 women, with a mean age of 60.7 ± 15.3 years old. Twenty nine (40.8%) cases were benign and 42 (59.2%) cases malignant. For a cutoff level of 37 U/ml the sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) to differentiate benign from malignant disease was 81%, 72.4%, 81% and 72.4%, respectively. For a cut off level of 130 U/ml specificity and PPV increased to 96.6% and 96.4%, respectively. Conclusions: The use of CA 19-9 is useful in the diagnosis of patients with suspected bilio-pancreatic malignant disease. The optimization of the normal published value can help to improve accuracy.

Lara-Diaz V.J.,Monterrey Institute of Technology | Vega-Mendez J.D.L.,Monterrey Institute of Technology | Vega-Mendez J.D.L.,Servicio Of Laboratorio Clinico | Arizaga-Ballesteros V.,Monterrey Institute of Technology | And 2 more authors.
International Journal of Infectious Diseases | Year: 2013

Objectives: To study the potential of buffy coat culture as a diagnostic tool for neonatal late-onset sepsis. Methods: This was a study of diagnostic accuracy in newborn infants born at 28-41 weeks of gestation, weighing >800. g, with ≥8 points on the NOSEP-1 scale. Paired samples for total blood culture (TBC) and buffy coat culture were drawn. We established the positivity rate, sensitivity, specificity, predictive values, and likelihood ratios, and compared time to positivity and contamination rates. Results: Fifty-two newborns were included in the study. Twenty-one TBC and 22 buffy coat cultures were positive. The positivity rate for TBC was 40.4% and for buffy coat culture was 42.3% (p=. not significant). Three TBC were positive with negative buffy coat culture. Four buffy coat cultures were positive with negative TBC; Kappa agreement was 0.723, p <0.001. Buffy coat culture sensitivity was 86% (95% confidence interval (CI) 68.5-95.4%), specificity 87% (75.4-93.7%), positive predictive value 82% (65.4-91.1%), negative predictive value 90% (77.9-96.8%), positive likelihood ratio 6.64 (2.79-15.05), and negative likelihood ratio 0.16 (0.05-0.42). We found no difference in time to positivity in hours; Wilcoxon Z=. 1224, p=. 0.22. The contamination rate was 1.9% for both methods. Conclusions: Buffy coat culture is as good as TBC for the microbiological diagnosis of late-onset sepsis of the newborn. Buffy coat culture allows the use of remaining plasma for further analysis. © 2012 International Society for Infectious Diseases.

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