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Duarte-Salazar C.,Servicio de Reumatologia Pediatrica | Santillan-Chapa C.G.,Servicio de Rehabilitacion Pediatrica | Marin-Arriaga N.,Instituto Nacional Of Rehabilitacion | Vazquez-Meraz J.E.,Institute Salud Del Estado Of Mexico
Cirugia y Cirujanos | Year: 2012

Background: acute lymphoblastic leukemia initially shows osteoarticular manifestations. However, it is rare that it shows juvenile idiopathic arthritis (JIA) symptoms. Clinical case: a child with acute lymphoblastic leukemia initially misdiagnosed with malignant neoplasia and septic arthritis, and later on with juvenile idiopathic arthritis. The child had persistent articular pain and swelling despite treatment. Six months later, a full blood count revealed leukopenia and neutropenia with lymphocytosis. A bone marrow aspirate confirmed pre-B acute lymphoblastic leukemia with hipodyploidia. Conclusion: this case initially showed typical signs of arthritis, and a diagnosis of acute lymphoblastic leukemia was ruled out, since the those clinical features and hematologic alterations characterizing this hematologic neoplasia. Source

Alcantara-Salinas A.,Servicio de Inmunologia y Alergia Pediatrica | Solano-Fiesco L.,Servicio de Reumatologia Pediatrica | Romero-Ramirez J.A.,Servicio de Reumatologia Pediatrica | Olive-ra-Solorzano F.,Servicio de Cardiologia Pediatrica | And 3 more authors.
Revista Alergia Mexico | Year: 2012

Neonatal lupus has a rare incidence, distinct from systemic lupus erythematosus. This is an acquired autoimmune disease associated with maternal antibodies to proteins Ro / La (SSA / SSB), transferred by the placenta; it represents the prototype of passive transfer of antibodies from mother to child. The disease can affect the skin, heart, and rarely, the hepatobiliary or hematologic systems. Congenital complete heart block is the most severe form of neonatal lupus. In clinical practice it is important to distinguish in utero a complete from an incomplete atrioventricular block (AV) in order to render prompt care. We present the case of a newborn female, who was diagnosed with an atrio-ventricular block at 26 weeks' gestation. When the baby was delivered at 38 weeks' gestation, she presented bradycardia (54 x×). On the suspicion of neonatal lupus, we required antinuclear antibodies, anti-Sm, anti-RNP, anti-SS-A and anti-SS-B, which were positive. A bicameral pacemaker was placed uneventfully. Source

Vega-Cornejo G.,Servicio de Reumatologia Pediatrica | Meza-Beltran J.,Servicio de Reumatologia Pediatrica
Reumatologia Clinica | Year: 2015

Takayasu Arteritis is a vasculitis that affects the aorta, and its large branches, including renal, coronary and pulmonary arteries. This is a case report of a newborn who had early onset sepsis, vascular imaging reported aneurysms in the thoracic and abdominal aorta, with decreased distal pulses, a blood pressure difference >10. mmHg and angiographic changes, integrating the diagnose of Takayasu's Arteritis. © 2014 Elsevier España, S.L.U. Source

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