Veinte de Noviembre (Santa Lucía), Mexico
Veinte de Noviembre (Santa Lucía), Mexico

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Paez-Aguirre S.F.,Servicio de Oncologia Pediatrica | Reyes-Barbosa D.A.,Coordinacion de Pediatria | Archundia-Gonzalez A.T.,Servicio de Radiologia e Imagen
Gaceta Mexicana de Oncologia | Year: 2010

A female adolescent with nodular sclerosing Hodgkin's lymphoma associated with thymofibrolipoma. She started with general symptoms, peripherical adenopathy and mediastinal mass; the treatment was chemo and radiotherapy, symptoms and peripherical adenopathy disappeared, but mediastinal mass persisted, a biopsy was made with diagnostic of thymofibrolipoma.


Gonzalez-Paredes Y.J.,Residencia de la Especialidad de Pediatria | Arreguin-Gonzalez F.E.,Servicio de Oncologia Pediatrica | Salamanca-Garcia M.,Servicio de Anatomia Patologica | Paez-Aguirre S.F.,Residencia de la Especialidad de Pediatria
Gaceta Mexicana de Oncologia | Year: 2014

Hodgkin lymphoma (HL) accounts for 9% of malignancies in pediatric patients. It is more frequent in males and its clinical presentation has 2 peaks. The first one is between the second and third decade, and the second peak is around 60 years old. Most of the neoplastic mass is constituted by an infiltrate of inflammatory cells and fibrosis, while malignant cells represent only 0.1% to 10% of the cell population. The Reed Sternberg cell is a classic finding in HL. We report a case of a female teenager who develops an obstructive acute renal failure due to a retroperitoneal nodal conglomerate which was identified as mixed cellularity subtype of HL (MCHL). In this patient the association with hypereosinophilic syndrome (HES) was also found. A third of patients with HL initially presents as an abdominal primary tumor. Hypereosinophylic syndrome as a paraneoplastic disorder is found in 15% of all cases. In order to make this diagnosis, leukemia, allergic diseases and parasitic infections must be excluded. In our patient the management with steroids and HL specific chemotherapy resulted in a satisfactory response observed in the reduction of the eosinophil count and size of linfadenopathies. The acute renal failure was resolved with peritoneal dialysis without tissue injury of the kidney so, it was not affected by the hypereosinophylic syndrome. Renal tissue involvement is not described as a typical finding in HES. © 2014 Gaceta Mexicana de Oncologia.


Paez-Aguirre S.F.,Servicio de Oncologia Pediatrica | Archundia-Gonzalez A.T.,Servicio de Radiologia e Imagen
Gaceta Mexicana de Oncologia | Year: 2011

Primitive neuroectodermal tumor of the central nervous system is an aggressive tumor; leptomeningeal seeding is common but extraneural metastases are rare. When these occur the most common sites are bone, lung, bone marrow, and lymph nodes. This is a report of a boy with a supratentorial PNET and extraneural metastasis.

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