Servicio de Aparato Digestivo

San Mamés de Burgos, Spain

Servicio de Aparato Digestivo

San Mamés de Burgos, Spain
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Perea Horno M.A.,Servicio Of Prevencion Of Riesgos Laborales Del Banco Of Espana | Marchesi Solis M.E.,Servicio Of Prevencion Of Riesgos Laborales Del Banco Of Espana | Calvo Serrano C.,Servicio de Aparato Digestivo
Revista de la Asociacion Espanola de Especialistas en Medicina del Trabajo | Year: 2016

Objective: Screening of colorectal cancer in a working population, using the fecal occult blood by immunochemical test. Material and methods: it is made a descriptive and transversal study of workers over 50 years old. The population sample consisted in 1,065 people. All of them made the test once. The positive ones were sent to the gastroenterologist in order to have a colonoscopy. The results were studied with a multivariate logistic regression, to determine the existence or not of statistical significance among the test and other variables took into consideration. Results: 115 workers got a positive test. In 36 cases it was found a colonic polyposis affection, and in one case was detected an “in situ” adaenocarcinoma colonic. Conclusions: The test has high cost effectiveness and that is why it is recommended to apply it as a preventive diagnostic method in workers older 50 years. © 2016, Accion Medica S.A. All rights reserved.


Guevara-Noriega K.A.,Servicio de Angiologia y Cirugia Vascular | Velescu A.,Servicio de Angiologia y Cirugia Vascular | Zaffalon-Espinal D.T.,Servicio de Aparato Digestivo | Mateos-Torres E.,Servicio de Angiologia y Cirugia Vascular | And 2 more authors.
Cirugia y Cirujanos (English Edition) | Year: 2017

Background Aorto-enteric fistula is a rare and potentially lethal entity. Its presentation may be as an enteric-paraprosthetic fistula, due to injury in the gut caused by direct contact with the vascular prosthesis. Objective We report a case of enteric-paraprosthetic fistulae with the unusual finding of Candida parapsilosis as the only isolated pathogen. Clinical case A 65-year-old male, smoker, with aortobifemoral revascularisation with dacron due to aortoiliac occlusive disease, and re-intervention for thrombosis of left arm at 6 months. Hospitalisation at 22 months was required due to a toxic syndrome, which was diagnosed as enteric-paraprosthetic fistulae after complementary studies. The graft was removed and an extra-anatomic revascularisation was performed. Microbiology specimens taken from the duodenal segment in contact with the prosthesis showed the prosthetic segment and peri-prosthetic fluid were positive to C. parapsilosis. Discussion The finding of C. parapsilosis in all cultures taken during surgery, along with negative blood cultures and no other known sources of infection, is of interest. It is an unusual pathogen with low virulence and limited as regards other Candida species. Our patient had no clinical data common to cases of infection with C. parapsilosis, and the mechanism of graft infection is unknown. Conclusion Graft infection by C. parapsilosis may be anecdotal. However, its consequences can also be severe. Microbiological tests can be useful to adjust antimicrobial therapy in the post-operative period, but their usefulness for determining the aetiology is doubtful, as it may be just an incidental finding. © 2016 Academia Mexicana de Cirugía A.C.


Guevara-Noriega K.A.,Servicio de Angiologia y Cirugia Vascular | Velescu A.,Servicio de Angiologia y Cirugia Vascular | Zaffalon-Espinal D.T.,Servicio de Aparato Digestivo | Mateos-Torres E.,Servicio de Angiologia y Cirugia Vascular | And 2 more authors.
Cirugia y Cirujanos (English Edition) | Year: 2016

Background: Aorto-enteric fistula is a rare and potentially lethal entity. Its presentation may be as an enteric-paraprosthetic fistula, due to injury in the gut caused by direct contact with the vascular prosthesis. Objective: We report a case of enteric-paraprosthetic fistulae with the unusual finding of Candida parapsilosis as the only isolated pathogen. Clinical case: A 65-year-old male, smoker, with aortobifemoral revascularisation with dacron due to aortoiliac occlusive disease, and re-intervention for thrombosis of left arm at 6 months. Hospitalisation at 22 months was required due to a toxic syndrome, which was diagnosed as enteric-paraprosthetic fistulae after complementary studies. The graft was removed and an extra-anatomic revascularisation was performed. Microbiology specimens taken from the duodenal segment in contact with the prosthesis showed the prosthetic segment and peri-prosthetic fluid were positive to C. parapsilosis. Discussion: The finding of C. parapsilosis in all cultures taken during surgery, along with negative blood cultures and no other known sources of infection, is of interest. It is an unusual pathogen with low virulence and limited as regards other Candida species. Our patient had no clinical data common to cases of infection with C. parapsilosis, and the mechanism of graft infection is unknown. Conclusion: Graft infection by C. parapsilosis may be anecdotal. However, its consequences can also be severe. Microbiological tests can be useful to adjust antimicrobial therapy in the post-operative period, but their usefulness for determining the aetiology is doubtful, as it may be just an incidental finding. © 2016 Academia Mexicana de Cirugía A.C.


Background: There are no simple and validated instruments for evaluating the training of specialists. Objectives: To analyze the reliability and validity of a computerized self-assessment method to quantify the acquisition of medical competences during the Internal Medicine residency program. Methods: All residents of our department participated in the study during a period of 28 months. Twenty-two questionnaires specific for each rotation (the Computer-Book of the Internal Medicine Resident) were constructed with items (questions) corresponding to three competence domains: clinical skills competence, communication skills and teamwork. Reliability was analyzed by measuring the internal consistency of items in each competence domain using Cronbach's alpha index. Validation was performed by comparing mean scores in each competence domain between senior and junior residents. Cut-off levels of competence scores were established in order to identify the strengths and weaknesses of our training program. Finally, self-assessment values were correlated with the evaluations of the medical staff. Results: There was a high internal consistency of the items of clinical skills competences, communication skills and teamwork. Higher scores of clinical skills competence and communication skills, but not in those of teamwork were observed in senior residents than in junior residents. The Computer-Book of the Internal Medicine Resident identified the strengths and weaknesses of our training program. We did not observe any correlation between the results of the self- evaluations and the evaluations made by staff physicians. Conclusions: The items of Computer-Book of the Internal Medicine Resident showed high internal consistency and made it possible to measure the acquisition of medical competences in a team of Internal Medicine residents. This self-assessment method should be complemented with other evaluation methods in order to assess the acquisition of medical competences by an individual resident. © 2012 Elsevier España, S.L. All rights reserved.


PubMed | Hospital Of Navarra, Hospital Germans Trias i Pujol, Hospital Clinico Of Zaragoza, Hospital Universitario Puerta del Mar and 15 more.
Type: Clinical Trial, Phase IV | Journal: Gastroenterologia y hepatologia | Year: 2015

GIDEON is a non-interventional, prospective, international study that evaluated the safety of sorafenib in patients with unresectable hepatocellular carcinoma (HCC) in daily clinical practice, including Child-Pugh B patients.To analyze data collected in Spain on the safety and efficacy of sorafenib and treatment patterns.Data were collected during follow-up on demographic and disease characteristics, the initial dose used, treatment-emergent adverse events (AEs) and dose modifications. Overall survival was evaluated, as well as time to disease progression. Efficacy and safety were analyzed according to the Child-Pugh classification and the initial dose.We included 143 patients from 19 Spanish hospitals. A total of 24.5% of the patients were Child-Pugh B. An initial dose of 400 mg/12 h was used in 90.9% of patients. In Child-Pugh A patients, dose modifications occurred more frequently and the treatment duration was longer. The incidence of AEs and drug-related AEs were similar in Child-Pugh A and B patients, although serious AEs were more frequent in Child-Pugh B patients. The most common AEs were diarrhea, fatigue and hand-foot skin reactions. The median overall survival was 384 days and was higher in Child-Pugh A patients (593 vs. 211 days in Child-Pugh B). The median time to disease progression was 177 days, similar in both subgroups.The safety profile of sorafenib in Spanish patients with unresectable HCC is independent of liver function. Child-Pugh status does not seem to influence the approach to sorafenib dosage or time to progression but does seem to be a strong prognostic factor for survival.


Vergara M.,Servei Aparell Digestiu | Vergara M.,Autonomous University of Barcelona | Vergara M.,CIBER ISCIII | Sicilia B.,Servicio de Aparato Digestivo | And 9 more authors.
Inflammatory Bowel Diseases | Year: 2016

Background: The aim was to develop and validate a self-reported short Crohn's disease work disability questionnaire (sCDWDQ). Methods: (1) Development of a shortened questionnaire - Patients' responses to the validation process (n 108) of a previously developed, 16-item Spanish Crohn's disease work disability questionnaire (CDWDQ) were analyzed using the Rasch model for multiple response items. After this process, a 9-item sCDWDQ was obtained. (2) Validation phase - The validation assessed the questionnaire's convergent validity, discriminant validity, test-retest reproducibility, and internal consistency. Spearman rank correlation, t test, intra-class correlation and Cronbach's alpha were used for the analysis. Results: One hundred fifty-one patients were included in the validation phase. (1) Convergent validity was confirmed by correlations between the sCDWDQ and clinical activity (r 0.66, P < 0.01), the short inflammatory bowel disease questionnaire IBDQ-9 (r 0.74, P < 0.001), Euroqol-5D (r 0.63, P < 0.01), the EuroQol-5D visual analog scale (r 0.54, P < 0.01), and overall work impairment (r 0.66, P < 0.01); (2) Discriminant validity - sCDWDQ scores were higher in patients with active disease (20.1 ± 6.3 versus 13.0 ± 3.8 inactive, P < 0.001), in those requiring previous sick leave (19.6 ± 6.9 versus no sick leave 14.2 ± 4.8, P < 0.01) and in those requiring hospitalization (20.0 ± 7.3 [n 29] versus no hospitalization 14.1 ± 7.3 [n 90], P < 0.01); (3) Internal consistency was also good (Cronbach's alpha 0.92); and (4) Reproducibility - sCDWDQ measures obtained 2 weeks apart showed an excellent intraclass correlation coefficient of 0.92 (95% confidence interval, 0.90-0.94). Conclusions: The self-reported sCDWDQ appears to be a simple, valid, and reliable tool for measuring work disability in Crohn's disease. © 2016 Crohn's & Colitis Foundation of America, Inc.


PubMed | Servicio de Angiologia y Cirugia Vascular and Servicio de Aparato Digestivo
Type: | Journal: Cirugia y cirujanos | Year: 2016

Aorto-enteric fistula is a rare and potentially lethal entity. Its presentation may be as an enteric-paraprosthetic fistula, due to injury in the gut caused by direct contact with the vascular prosthesis.We report a case of enteric-paraprosthetic fistulae with the unusual finding of Candida parapsilosis as the only isolated pathogen.A 65-year-old male, smoker, with aortobifemoral revascularisation with dacron due to aortoiliac occlusive disease, and re-intervention for thrombosis of left arm at 6 months. Hospitalisation at 22 months was required due to a toxic syndrome, which was diagnosed as enteric-paraprosthetic fistulae after complementary studies. The graft was removed and an extra-anatomic revascularisation was performed. Microbiology specimens taken from the duodenal segment in contact with the prosthesis showed the prosthetic segment and peri-prosthetic fluid were positive to C. parapsilosis.The finding of C. parapsilosis in all cultures taken during surgery, along with negative blood cultures and no other known sources of infection, is of interest. It is an unusual pathogen with low virulence and limited as regards other Candida species. Our patient had no clinical data common to cases of infection with C. parapsilosis, and the mechanism of graft infection is unknown.Graft infection by C. parapsilosis may be anecdotal. However, its consequences can also be severe. Microbiological tests can be useful to adjust antimicrobial therapy in the post-operative period, but their usefulness for determining the aetiology is doubtful, as it may be just an incidental finding.


PubMed | Servicio de Aparato Digestivo, Hospital Clinico Universitario Of Zaragoza and Autonomous University of Barcelona
Type: Journal Article | Journal: United European gastroenterology journal | Year: 2015

Data on the prevalence of work disability in patients with inflammatory bowel disease (IBD) are heterogeneous. As most studies have been performed in selected, often severe, IBD patients, the true prevalence of disability in the community remains controversial. The aim of this cross-sectional study was to evaluate the prevalence and severity of disability and its predictive factors in a community-based IBD population.Patients recorded in the community-based IBD register at the Hospital Universitario de Burgos were contacted. After informed consent they completed a set of questionnaires including demographic, clinical, disability and quality of life data. The statistical study was performed using SPSS 21.A total of 293 patients were included - 151 Crohns disease (CD), 142 ulcerative colitis (UC), 137 female, mean age: 4511 years, mean time since diagnosis: 10.611 years. Twelve patients (4.1%) had a work-disability pension. In addition, 93 (32%) of all patients had an officially recognized disability degree, which was generally moderate (n=73, 25%) or severe (N=16, 5%). Age, time since IBD diagnosis, CD, perianal disease, incontinence, active disease, the need for anti-TNF or psychological treatment, previous surgeries and the number of diagnostic tests and medical visits in the previous year were predictors of disability. Major predictors of qualifying for a disability pension were age, IBD activity, incontinence, need for biological drugs and ostomy.Mild to moderate work disability is frequent in IBD. However, only a minority of patients develop severe disability qualifying them for a pension.

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