Claus M.G.,Ghent University |
Feron E.,Service of Ophthalmology |
Veckeneer M.,Service of Ophthalmology
Eye (Basingstoke) | Year: 2017
Purpose To study the efficacy of a single intravitreal injection of expansile gas as a valuable alternative to current treatment options (conservative, pharmacological, and surgical) in patients with symptomatic, focal vitreomacular traction (VMT). Patients and methods This study comprises a retrospective, interventional case series of patients. Twenty eyes in seventeen patients with symptomatic and persisting focal VMT were treated in an outpatient setting with an intravitreal gas injection of 0.2 ml. In 19 eyes, 100% hexafluoroethane (C2F6) was used. One eye received sulfur hexafluoride (SF6). To all but three patients posturing advice was given. Patients were reviewed with a full-eye examination and ocular coherence tomography (OCT) after 14 days and later. The primary outcome measure was the release of VMT on OCT. Results In 17 of the 20 (85.0%) treated eyes, a release of VMT was achieved as documented on OCT. The release of VMT was diagnosed during the first month after injection in 11 eyes of 11 patients and within 3 months in 16 eyes of 15 patients. In all but five of our patients, best corrected visual acuity (BCVA) remained stable or improved. In four patients, the progression or development of cataract was the probable cause of the decrease in BCVA. One patient developed a stage II macular hole after injection and needed vitrectomy. None of the treated patients developed retinal breaks. Conclusion Intravitreal expansile gas injection could offer a minimally invasive, low-cost alternative treatment in patients with symptomatic, persisting VMT. Additional studies on a larger number of patients are required. © 2017 Macmillan Publishers Limited, part of Springer Nature. All rights reserved.
PubMed | Service of Ophthalmology and Ghent University
Type: | Journal: Eye (London, England) | Year: 2016
PurposeTo study the efficacy of a single intravitreal injection of expansile gas as a valuable alternative to current treatment options (conservative, pharmacological, and surgical) in patients with symptomatic, focal vitreomacular traction (VMT).Patients and methodsThis study comprises a retrospective, interventional case series of patients. Twenty eyes in seventeen patients with symptomatic and persisting focal VMT were treated in an outpatient setting with an intravitreal gas injection of 0.2ml. In 19 eyes, 100% hexafluoroethane (C
Bouledjfane B.,Annaba University |
Bennacer L.,Annaba University |
Kahli M.S.,Service of Ophthalmology
2013 8th International Workshop on Systems, Signal Processing and Their Applications, WoSSPA 2013 | Year: 2013
Image sharpening is the essential preprocessing step when improving the angiographies retinal image quality. It is helpful for the vessel retinal analysis and for improving the quality of their. For this reason, we propose a new technique for image sharpening based on Unsharp Masking (UM), and Bidimensional Empirical Mode Decomposition (BEMD). Firstly, the image is decomposed into a set of bidimensional intrinsic mode functions (BIMFs) and the residual image. Afterward, a weighting mask is achieved from an edge map multiplied by a compensation factor. Then, we apply the weighting mask to the first mode. Finally, we perform the reconstruction of the sharpened image by summing the compensated BIMF1 with the rest of the other modes and the residual image. The proposed scheme is enhanced by means of deringing's step to overcome the overshooting introduced during image sharpening. The obtained results proved that the proposed approach is effective to sharpen retinal images. © 2013 IEEE.
Baroni L.V.,Hospital JP Garrahan |
Sampor C.,Hospital JP Garrahan |
Fandino A.,Service of Ophthalmology |
Solernou V.,Service of Pathology |
And 3 more authors.
Journal of Pediatric Hematology/Oncology | Year: 2014
We report a retrospective review of patients with retinoblastoma and anterior segment invasion (ASI) as risk factors for extraocular relapse. Only those with ASI combined with postlaminar optic nerve invasion and/or scleral invasion received adjuvant chemotherapy and those with tumor at the resection margin received orbital radiotherapy. Those with only uveal invasion did not receive adjuvant therapy. Of 479 evaluable patients, 67 patients had pathologically confirmed ASI, including 52 with anterior chamber invasion and 47 with iris or ciliary body invasion. ASI occurred with other pathology risk factors (25 had concomitant posterior uveal invasion, 36 had postlaminar optic nerve invasion, 11 with cut-end invasion, and 25 with scleral invasion). The 5-year disease-free survival (pDFS) was 0.9 (95% CI, 0.8-0.95) for children with ASI with no significant differences among children with other pathology risk factors with and without ASI. ASI was not significantly associated with extraocular relapse in multivariate analysis. There were no significant differences in pDFS for patients with anterior chamber invasion and those with iris-ciliary body invasion (pDFS 0.89 [95% CI, 0.65-0.96] vs. 0.93 [95% CI, 0.61-0.98]). To conclude, ASI was seen with other pathology risk factors and it did not add a significant risk for extraocular relapse. Copyright © 2014 by Lippincott Williams & Wilkins.