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Hammam Sousse, Tunisia

Bouhabel A.,University of Mentouri Constantine | Laib Z.,Service dEpidemiologie | Hannache K.,Service de Medecine Interne | Aberkane A.,CHU de Constantine
Nephrologie et Therapeutique | Year: 2014

End-stage renal failure is considered a public heath problem that constitutes a heavy cost on communities worldwide. To be able to plan the treatment of this pathology, we must have reliable and updated information through health network which represents the best mean for planning and reflexion locally and nationwide. The aim of our study was to answer to this need through a local registry of renal replacement therapy and nephrology network that we have for the first time an inventory of this pathology in an Algerian town (Constantine), and in this article we present the first results concerning patients under chronic hemodialysis. Source


Bendjemana K.,University of Khenchela | Satta D.,University of Mentouri Constantine | Adjabi K.,University of Khenchela | Miali A.,University of Khenchela | And 2 more authors.
Journal Africain du Cancer | Year: 2011

Nasopharyngeal carcinoma (NPC) is one of the most important cancers in Algeria with 8 to 12 cases/ 100,000 persons a year. The pathogenesis of NPC is not clear. In Algeria and Tunisia, it represents the first most common cancer of the larynx in women and the second most common tumor inmen. This is a retrospective epidemiological study of the NPC in the North-East of Algeria and evaluates the impact of the consumption of some foods, tobacco and alcohol on the risk of development of NPC. The study of a group of 160 patients affected by NPC, using 205 people as a control group, has shown that this cancer was predominant in men, particularly in the population between 40- and 59-years-old. The analysis has shown that preservatives such askhliiseem to be a statistically significant factor related to NPC. Our results also show a strong association between alcohol consumption and tobacco use and the risk of developing NPC. However, we did not find a statistically significant relationship with other food factors. © 2011 Springer Verlag France. Source


Bensalem S.,Laboratoire Of Recherche Diab Suc | Lakehal A.,Service dEpidemiologie | Roula D.,Laboratoire Of Recherche Diab Suc
Medecine des Maladies Metaboliques | Year: 2014

Of 432 pregnant women screened according to WHO criteria, 6.3% [95% CI: 4.2 to 9.1] had a gestational diabetes (GDM). Referring to criteria developed by the International Association of Diabetes and Pregnancy Study Group (IADPSG) the GDM frequency reaches 14.6%. All screened GDM had risk factors. All of them are older than 25 years (mean age: 35.6±4.6 years) and multiparous and among them 81.5 % had a BMI >25 kg/m2. Their family and obstetric history are quite rich compared to non-diabetic pregnant women. Macrosomia was found in 22.2 % of GDM. The only two independent risk factors for macrosomia found in our diabetic population are fasting hyperglycemia and overweight. OGTT performed at 12 weeks postpartum in GDM revealed that 18.5% had abnormal glucose tolerance. In light of these results, targeted screening is required by economic necessity. During pregnancy the presence of risk factors such as encountered in our population: age >30 years, multiparity, BMI >27 kg/m2, 1st degree family diabetes history, obstetric personal history of GDM or macrosomia, hypertension or obesity should prompt a targeted and early detection of gestational diabetes. © 2014 - Elsevier Masson SAS - Tous droits réservés. Source


Ramel J.-C.,Service dOphtalmologie | Bron A.-M.,Service dOphtalmologie | Isaico R.,Service dOphtalmologie | Meillon C.,Service dOphtalmologie | And 2 more authors.
Journal Francais d'Ophtalmologie | Year: 2014

Introduction Endophthalmitis is the most dreaded complication after intravitreal injection. With the rise of antiangiogenics their rate is getting higher each year. The use of antibioprophylaxis is controversial. We tried to evaluate the impact of antibioprophylaxis on intravitreal injection endophthalmitis incidence. Methods All patients who received intravitreal injections between January 2007 and October 2012 were included in this retrospective study. Until June 2012 all patients had antibiotics the days following the injection. From July 2012 the antibiotic was replaced by an antiseptic immediately after the injection. Results An overall number of 11,450 injections were performed. The overall rate of endophthalmitis was 6/11,450 (0.052%). The incidence of endophthalmitis in the group with antibiotics was 3/10,144 injections (0.03%), 2 were culture proven (0.02%). The incidence in the group without antibiotics was 3/1306 (0.23%). The difference was significant (P = 0.024). Conclusion The incidence of endophthalmitis post-intravitreal injections seems to be lower when using antibiotics. However, a prospective study is mandatory to draw more robust conclusions. © 2014 Elsevier Masson SAS. Tous droits réservés. Source


Ouhadj O.,Service dOphtalmologie | Bouarfa A.,Service dOphtalmologie | Akel S.,Service dOphtalmologie | Mendil L.,Service dOphtalmologie | And 2 more authors.
Journal Francais d'Ophtalmologie | Year: 2010

Introduction: Macular choroidal neovascularization (CNV) is a serious complication of high myopia, compromising the visual prognosis in young patients. The purpose of this study was to evaluate the safety and efficacy of first-line intravitreal ranibizumab in the treatment of myopic CNV. Patients and methods: We conducted a single-center prospective, consecutive, interventional study of patients with subfoveal or juxtafoveal CNV secondary to pathologic myopia (PM) treated with intravitreal injection of ranibizumab in the Beni-Messous University Hospital from January 2009 to April 2010. Best-corrected visual acuity (BCVA), fundus examination, optical coherence tomography (OCT), and fluorescein angiography (FA) were performed at baseline and monthly for all patients. Indications for retreatment were persistence or recurrence of the neovascular activity. Results: The study included 40 eyes of 40 patients, 33 of whom were females (82.5%), with a mean age of 40.22 ± 10.81 years (range, 20-55 years), with visual acuity between 1/100 and 1/10. The mean spherical equivalent refractive error was -14.13 ± 4.65 diopters (range, -7 D to -23 D). The mean follow-up time was 8 months (range, 3-15 months). The mean number of intravitreal injections administered for each patient was 2.2 (range: 1-4). Follow-up ranged from 3 to 15 months (mean, 8 months). All patients maintained or improved their vision; the average gain in visual acuity was three lines (range: 1-9 lines). No injection complications or drug-related side effects were noted during the follow-up period. Discussion: Intravitreal ranibizumab to treat CNV complicated by high myopia seems to be associated with an improvement in VA and good tolerance. This study confirms the efficacy of first-line anti-VEGF, in particular, ranibizumab in this indication. Conclusion: In this series of eyes with limited follow-up, intravitreal ranibizumab was a safe and effective treatment for CNV secondary to PM, resulting in functional and anatomic improvement. © 2010 Elsevier Masson SAS. Tous droits réservés. Source

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