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Pierard-Franchimont C.,Service de Dermatopathologie | Pierard G.E.,University of Liege | Pierard G.E.,University of Franche Comte
Revue Medicale de Liege | Year: 2012

Treating a patient with cutaneous malignant melanoma relies on the recognition of a clever stratification of the distinct stages of the disease. The histoprognostic criteria were recently revisited. In addition, translational research fueled the development of new treatments with at last increased efficacy in the metastatic stage. Such therapeutic advance improves the median overall survival for a few months. Some combined treatments could possibly boost the beneficial effects. Source


Pierard G.E.,University of Liege | Pierard G.E.,University of Franche Comte | Pierard-Franchimont C.,Service de Dermatopathologie | Delvenne P.,Service de Dermatopathologie
Revue Medicale de Liege | Year: 2014

The frontier between the human body and the environment is largely represented by the stratum corneum. It is obvious that the skin aspect on some body sites appears dry and rough in some predisposed individuals during winter season. The reductions in the outdoor temperature, ambient moisture and dew point are the main physical factors involved in this process. We present the aspects seen under ultraviolet light and scanning electron microscopy. Source


Pierard-Franchimont C.,Service de Dermatopathologie | Quatresooz P.,Service de Dermatopathologie | Reginster M.A.,Service de Dermatopathologie | Pierard G.E.,Service de Dermatopathologie | Pierard G.E.,University of Franche Comte
Revue Medicale de Liege | Year: 2011

Drug eruptions are frequently encountered. Ttheir putative diagnosis is based on a set of imputability arguments. Tthe histopathological aspect is often evocative of the nature of the dermatosis. It varies according to the type of drug reaction. Ssome drug eruptions follow a benign course, but others are life-threatening. Source


Pierard-Franchimont C.,Service de Dermatopathologie | Hermanns J.-F.,Service de Dermatopathologie | Pierard G.E.,Service de Dermatopathologie | Pierard G.E.,University of Franche Comte
Revue Medicale de Liege | Year: 2011

Ritual and artistic tattoos rely on the use of numerous pigments which are not all entirely inert once placed in the dermis. The compositions of some tattoo inks are identified. However, new but less well identified compounds appear on the market. Allergic reactions can be present under different aspects. They may correspond to allergic contact dermatitis or to photodermatitis. Other reactions include allergic hypersensitivity reactions as well as lichenoid, granulomatous or pseudolymphoma reactions. Pulsed light and laser are typically used for regular tattoo removal. These procedures are not indicated in inflamed tattoos. indeed, the pigment dispersed during photolysis may perpetuate the reaction. Pseudotattoos due to the stratum corneum staining are frequently responsible for photoeczema. Source


Pierard-Franchimont C.,Service de Dermatopathologie | Pierard G.E.,Service de Dermatopathologie | Pierard G.E.,University of Franche Comte
Revue Medicale de Liege | Year: 2011

Malignant melanoma developed after 60 years of age is not a rare neoplasm. It is mainly but not exclusively represented by the lentigo maligna (LM) and the invasive melanoma developed on LM (LMM). Men are more often affected, and chronic sun exposure is the main cause. The diagnosis relies on the clinical, dermoscopic and dermatopathologic examinations. surgical excision is recommended but alternative treatments are possible in case of contra-indication. Source

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