Pertinence of the preoperative exploration in the evaluation of the risk of lymph node metastasis in endometrial cancer [Pertinence du bilan préoperatoire dans l'évaluation du risque de métastases ganglionnaires d'un cancer endométrial]
Groff B.,Service de Chirurgie Gynecologique et Oncologique |
Pouget O.,Nimes University Hospital Center |
Stoll F.,Service de Chirurgie Gynecologique et Oncologique |
Mathelin C.,Service de Senologie et de Pathologie Mammaire |
And 2 more authors.
Gynecologie Obstetrique Fertilite | Year: 2014
Purpose To assess the relevance of MRI, endometrial biopsy and curettage in the diagnosis of endometrial cancer at high risk of lymph node metastasis. Patients and methods A retrospective study on continuous series of patients treated for endometrial cancer limited to the uterus between 2004 and 2008, results of preoperative evaluation of tumor stage using MRI, histological type and grade by endometrial curettage and biopsies were compared to final histological examination. Results One hundred and sixty-nine patients were included in the study. Ninety (53.3%) had MRI, 112 (66.2%) curettage and 61 (36.6%) endometrial biopsy using Pipelle de Cornier®. Sensibility (SN), specificity (SP), positive (PPV) and negative predictive values (NPV) of MRI, in the diagnosis of endometrial cancer at high risk of lymph nodes metastases were of 65.6%, 87.2%, 77.7%, 79.2%. For EB and curettage SN, SP, PPV and NPV were of 42.9%, 96.9%, 85%, 79.5%; 80.6%, 98.3%, 96.2% and 90.6% respectively. 37.8% of cancers diagnosed to be at low risk of lymph node metastasis were at high risk in definitive histologic examination. Discussion and conclusion Preoperative evaluation by MRI, endometrial curettage and biopsy has good diagnostic value in the identification of endometrial cancer susceptible to benefit from lymphadenectomy. Underestimation, however, is encountered in approximately one third of cases. Source
Cohen-Mouly S.,Service de Chirurgie Gynecologique et Oncologique |
Cohen-Mouly S.,University of Paris Descartes |
Badia A.,Service de chirurgie thoracique |
Badia A.,University of Paris Descartes |
And 12 more authors.
Bulletin du Cancer | Year: 2010
As seventy-five percent of patients with ovarian cancer are diagnosed at an advanced stage (FIGO stage III/IV), optimal surgery is then difficult to perform. The aim of our study is to assess the interest of thoracoscopy in the management of ovarian carcinoma with pleural effusion. ©John Libbey Eurotext. Source