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Maria de la Salut, Spain

Wellesley D.,University of Southampton | Dolk H.,University of Ulster | Boyd P.A.,University of Oxford | Greenlees R.,University of Ulster | And 13 more authors.
European Journal of Human Genetics | Year: 2012

The aim of this study is to quantify the prevalence and types of rare chromosome abnormalities (RCAs) in Europe for 2000-2006 inclusive, and to describe prenatal diagnosis rates and pregnancy outcome. Data held by the European Surveillance of Congenital Anomalies database were analysed on all the cases from 16 population-based registries in 11 European countries diagnosed prenatally or before 1 year of age, and delivered between 2000 and 2006. Cases were all unbalanced chromosome abnormalities and included live births, fetal deaths from 20 weeks gestation and terminations of pregnancy for fetal anomaly. There were 10 323 cases with a chromosome abnormality, giving a total birth prevalence rate of 43.8/10 000 births. Of these, 7335 cases had trisomy 21,18 or 13, giving individual prevalence rates of 23.0, 5.9 and 2.3/10 000 births, respectively (53, 13 and 5% of all reported chromosome errors, respectively). In all, 473 cases (5%) had a sex chromosome trisomy, and 778 (8%) had 45,X, giving prevalence rates of 2.0 and 3.3/10 000 births, respectively. There were 1 737 RCA cases (17%), giving a prevalence of 7.4/10 000 births. These included triploidy, other trisomies, marker chromosomes, unbalanced translocations, deletions and duplications. There was a wide variation between the registers in both the overall prenatal diagnosis rate of RCA, an average of 65% (range 5-92%) and the prevalence of RCA (range 2.4-12.9/10 000 births). In all, 49% were liveborn. The data provide the prevalence of families currently requiring specialised genetic counselling services in the perinatal period for these conditions and, for some, long-term care. © 2012 Macmillan Publishers Limited All rights reserved. Source

Lopez-Amoros M.,Servei de Salut Comunitaria | Schiaffino A.,Servei de Salut Comunitaria | Moncada A.,Servei de Salut Comunitaria | Perez G.,Servei de Sistemes dInformacio Sanitaria
Gaceta Sanitaria | Year: 2010

Objective: To describe factors associated with self-reported use of emergency contraception in adolescents attending school in the city of Terrassa (Barcelona, Spain) in 2008. Methods: We carried out a cross-sectional study to describe the health habits of teenage girls and boys attending school in Terrassa. A representative sample of adolescents aged between 14 and 18 years (n=1300) was used. The adolescents were administered a questionnaire designed ad hoc. Adolescents who reported having had sexual intercourse at least once were studied (n=390). The outcome variable was self-reported use of emergency contraception at some time. The explanatory variables provided information on sociodemographic characteristics, drug use and sexuality. The odds ratios (OR) and 95% confidence intervals (95% CI) were fitted using multivariate logistic regression models. The results were stratified by sex. Results: A total of 390 students, 28.2% girls and 20.1% boys (their partners) had used emergency contraception at some time. Among boys, the final multivariate model showed that emergency contraception was associated with alcohol abuse (OR=2.7; 95% CI:1.0-7.5), having sexual intercourse weekly (OR=2.8; 95% CI: 1.1-7.2) and not having discussed issues about sexuality in the classroom (OR=2.5; 95% CI: 1.0-6.5). Among girls, self-reported emergency contraception was associated with alcohol abuse (OR=2.7; 95% CI: 1.4-5.6), cannabis consumption (OR=3.1; 95% CI:1.6-6.0) and weekly sexual intercourse (OR=2.0; 95% CI: 1.1-3.9). Conclusion: Promotion and prevention strategies should begin as early as possible. Behavioral differences should be seen from a gender perspective in the fields of both research and program implementation. © 2010 SESPAS. Source

Puigpinos-Riera R.,Servei de Sistemes dInformacio Sanitaria | Puigpinos-Riera R.,CIBER ISCIII | Puigpinos-Riera R.,University of Barcelona | Mari-Dell'Olmo M.,Servei de Sistemes dInformacio Sanitaria | And 29 more authors.
International Journal of Health Geographics | Year: 2011

Background: Intra-urban inequalities in mortality have been infrequently analysed in European contexts. The aim of the present study was to analyse patterns of cancer mortality and their relationship with socioeconomic deprivation in small areas in 11 Spanish cities.Methods: It is a cross-sectional ecological design using mortality data (years 1996-2003). Units of analysis were the census tracts. A deprivation index was calculated for each census tract. In order to control the variability in estimating the risk of dying we used Bayesian models. We present the RR of the census tract with the highest deprivation vs. the census tract with the lowest deprivation.Results: In the case of men, socioeconomic inequalities are observed in total cancer mortality in all cities, except in Castellon, Cordoba and Vigo, while Barcelona (RR = 1.53 95%CI 1.42-1.67), Madrid (RR = 1.57 95%CI 1.49-1.65) and Seville (RR = 1.53 95%CI 1.36-1.74) present the greatest inequalities. In general Barcelona and Madrid, present inequalities for most types of cancer. Among women for total cancer mortality, inequalities have only been found in Barcelona and Zaragoza. The excess number of cancer deaths due to socioeconomic deprivation was 16,413 for men and 1,142 for women.Conclusion: This study has analysed inequalities in cancer mortality in small areas of cities in Spain, not only relating this mortality with socioeconomic deprivation, but also calculating the excess mortality which may be attributed to such deprivation. This knowledge is particularly useful to determine which geographical areas in each city need intersectorial policies in order to promote a healthy environment. © 2011 Puigpinós-Riera et al; licensee BioMed Central Ltd. Source

Serral G.,Servei de Sistemes dInformacio Sanitaria | Serral G.,Research Center Biomedica En Red Of Epidemiologia lud Publica | Serral G.,Biomedical Research Institute Sant Pau | Serral G.,University Pompeu Fabra | And 11 more authors.
Revista de Calidad Asistencial | Year: 2013

Objective: A good communication plan is vital for optimal results in any screening programme. The objective of this study was to assess the knowledge, involvement and opinion of health professionals regarding the Breast Cancer Screening Programme in Barcelona in 2008. Material and methods: A cross-sectional study using an anonymous and self-administered questionnaire. The study population (N = 960) were health professionals from Primary Health-care (PH), Programs for Sexual and Reproductive Health (PSRH), and Community Pharmacies (CP). The dependent variables were: knowledge of the Programme, professional involvement and opinion of the Programme. The independent variables were: sex, age, qualifications, employment status, and health team. A descriptive and bivariate analysis was performed. Using multivariate logistic regression models adjusted for age, an Odds Ratios (OR) were obtained along with the 95% confidence intervals (CI95%). Results: PSRH professionals know the target population better; 80.2% versus 26.1% PH, and 14.0% CP, respectively. Professional involvement was related to the health care team (ORCP/PH: 0.32, CI95%: 0.22-0.43) being observed more in PH. The opinion on the Programme in reducing breast cancer mortality was similar in the three teams (61.6% PH, 59.3% PSRH, and 56.5% CP). Conclusions: Healthcare professionals are unaware of some aspects of Programme, such as age range or periodicity. There is great professional involvement and belief that the Programme has helped disseminate information and knowledge on the early detection of breast cancer.© 2012 SECA. Publicado por Elsevier España, S.L. Todos los derechos reservados. Source

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