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Sert, Egypt

Fadda A.A.,Mansoura University | El-Mekabaty A.,Mansoura University | Elattar K.M.,Sert University
Synthetic Communications | Year: 2013

This review highlights the methods used for the synthesis of enaminonitriles of pyrano[2,3-c]pyrazole compounds. Their reactivity and synthetic importance were investigated. In this context, recent progress in the synthesis and use of enaminonitriles of pyrano[2,3-c]pyrazole as precursors for heterocyclic compounds is reviewed. The synthetic routes for preparation of enaminonitriles are based on multicomponent reactions including three- or four-component reactions. Enaminonitriles can be used as building blocks for carbocyclic five-, six-, and seven-membered heterocycles as well as fused heterocyclic compounds. The bibliography includes 94 references. © 2013 Taylor and Francis Group, LLC. Source


Gouda M.A.,Taibah University | Gouda M.A.,Mansoura University | Abu-Hashem A.A.,National Research Center of Egypt | Abu-Hashem A.A.,Jazan University | And 3 more authors.
Research on Chemical Intermediates | Year: 2016

This review presents a systematic and comprehensive survey of the method of preparation and the chemical reactivity of 5-chloropyrazole-4-carbaldehyde. These compounds are important intermediates for the synthesis of a variety of otherwise difficult to obtain, synthetically useful, and novel heterocyclic systems. Graphical Abstract: [Figure not available: see fulltext.] © 2015 Springer Science+Business Media Dordrecht. Source


Fadda A.A.,Mansoura University | Bayoumy N.M.,Mansoura University | Bayoumy N.M.,Delta University | Elattar K.M.,Mansoura University | Elattar K.M.,Sert University
Synthetic Communications | Year: 2015

This review is a broad overview of the chemistry of 2-tosylacetonitrile, which considered as a very reactive synthetic compound. The synthetic methods are reported. The reactions of the title compound lead to the preparation of a variety of heterocyclic ring systems, such as five-and six-membered ring systems containing one, two, or three heteroatoms. The reaction mechanisms are discussed. © 2015 Taylor and Francis Group, LLC. Source


Fadda A.A.,Mansoura University | Elattar K.M.,Mansoura University | Elattar K.M.,Sert University
Synthetic Communications | Year: 2016

This review reports the reactivity of dehydroacetic acid, which considered to be a very reactive organic compound. The structure of the title compound was investigated. The condensation reactions with primary amines led to the preparation of a variety of heterocyclic ring systems, including bispyran, pyrazole, thiazole, pyridine, pyrimidine, thiazine, thiazepine, and diazepine ring systems. On the other hand, the condensation reaction with aldehydes led to the formation of 1,5-benzodiazepines, pyran, and pyranopyran heterocyclic ring systems. The reaction mechanisms were discussed. The bibliography includes 130 references. © 2016 Taylor & Francis Group, LLC. Source


Fadda A.A.,Mansoura University | El-Hadidy S.A.,Mansoura University | Elattar K.M.,Mansoura University | Elattar K.M.,Sert University
Synthetic Communications | Year: 2015

This review reports a broad overview of the synthetic procedures of 1,8-naphthyridines, dibenzo[b,g][1,8]naphthyridine, dibenzo[c,f][1,8]naphthyridine, 1,8-naphthyridine-3-carboxylic acid, 1,8-naphthyridine-3-carboxamide, and 1,8-naphthyridine-3-carbohydrazide compounds and their reactions. The physical properties, spectral data, and biological importance of naphthyridines are discussed. Copyright © Taylor & Francis Group, LLC. Source

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