Sert University

Sert, Egypt

Sert University

Sert, Egypt

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Gouda M.A.,Taibah University | Gouda M.A.,Mansoura University | Abu-Hashem A.A.,National Research Center of Egypt | Abu-Hashem A.A.,Jazan University | And 3 more authors.
Research on Chemical Intermediates | Year: 2016

This review presents a systematic and comprehensive survey of the method of preparation and the chemical reactivity of 5-chloropyrazole-4-carbaldehyde. These compounds are important intermediates for the synthesis of a variety of otherwise difficult to obtain, synthetically useful, and novel heterocyclic systems. Graphical Abstract: [Figure not available: see fulltext.] © 2015 Springer Science+Business Media Dordrecht.


Fadda A.A.,Mansoura University | El-Mekabaty A.,Mansoura University | Mousa I.A.,South Valley University | Elattar K.M.,Sert University
Synthetic Communications | Year: 2014

This review highlighted the methods used for the synthesis of different heterocyclic compounds derived from 3-(1H-indol-3-yl)-3-oxopropanenitrile. The reactivity and their synthetic importance were investigated. In this context, recent progress in the synthesis and use of 3-(1H-indol-3-yl)-3- oxopropanenitrile as precursors for heterocyclic compounds is reviewed. © 2014 Copyright Taylor & Francis Group, LLC.


Fadda A.A.,Mansoura University | El-Mekabaty A.,Mansoura University | Elattar K.M.,Sert University
Synthetic Communications | Year: 2013

This review highlights the methods used for the synthesis of enaminonitriles of pyrano[2,3-c]pyrazole compounds. Their reactivity and synthetic importance were investigated. In this context, recent progress in the synthesis and use of enaminonitriles of pyrano[2,3-c]pyrazole as precursors for heterocyclic compounds is reviewed. The synthetic routes for preparation of enaminonitriles are based on multicomponent reactions including three- or four-component reactions. Enaminonitriles can be used as building blocks for carbocyclic five-, six-, and seven-membered heterocycles as well as fused heterocyclic compounds. The bibliography includes 94 references. © 2013 Taylor and Francis Group, LLC.


Fadda A.A.,Mansoura University | Abdel-Galil E.,Mansoura University | Elattar K.M.,Mansoura University | Elattar K.M.,Sert University
Synthetic Communications | Year: 2015

This review highlights the methods used for the synthesis of 3-oxo-N-(pyridin-2-yl)butanamide compounds. The reactivity and synthetic importance are investigated. In this context, recent progress in the synthesis and use of 3-oxo-N-(pyridin-2-yl)butanamide as precursors for heterocyclic compounds is reviewed. The synthetic routes for preparation of 3-oxo-N-(pyridin-2-yl)butanamide are based on the reaction of diketene with aromatic primary amine and reaction of 2-aminopyridine with β-keto-t-butylthioester or ethylacetoacetate. The bibliography includes 73 references. © 2015 Taylor and Francis Group, LLC.


Fadda A.A.,Mansoura University | Elattar K.M.,Mansoura University | Elattar K.M.,Sert University
Synthetic Communications | Year: 2016

This review reports the reactivity of dehydroacetic acid, which considered to be a very reactive organic compound. The structure of the title compound was investigated. The condensation reactions with primary amines led to the preparation of a variety of heterocyclic ring systems, including bispyran, pyrazole, thiazole, pyridine, pyrimidine, thiazine, thiazepine, and diazepine ring systems. On the other hand, the condensation reaction with aldehydes led to the formation of 1,5-benzodiazepines, pyran, and pyranopyran heterocyclic ring systems. The reaction mechanisms were discussed. The bibliography includes 130 references. © 2016 Taylor & Francis Group, LLC.


Fadda A.A.,Mansoura University | Bayoumy N.M.,Mansoura University | Bayoumy N.M.,Delta University for Science and Technology | Elattar K.M.,Mansoura University | Elattar K.M.,Sert University
Synthetic Communications | Year: 2015

This review is a broad overview of the chemistry of 2-tosylacetonitrile, which considered as a very reactive synthetic compound. The synthetic methods are reported. The reactions of the title compound lead to the preparation of a variety of heterocyclic ring systems, such as five-and six-membered ring systems containing one, two, or three heteroatoms. The reaction mechanisms are discussed. © 2015 Taylor and Francis Group, LLC.


Fadda A.A.,Mansoura University | El-Hadidy S.A.,Mansoura University | Elattar K.M.,Mansoura University | Elattar K.M.,Sert University
Synthetic Communications | Year: 2015

This review reports a broad overview of the synthetic procedures of 1,8-naphthyridines, dibenzo[b,g][1,8]naphthyridine, dibenzo[c,f][1,8]naphthyridine, 1,8-naphthyridine-3-carboxylic acid, 1,8-naphthyridine-3-carboxamide, and 1,8-naphthyridine-3-carbohydrazide compounds and their reactions. The physical properties, spectral data, and biological importance of naphthyridines are discussed. Copyright © Taylor & Francis Group, LLC.


Mahgoub A.F.,Cairo University | Issa A.Z.,Sert University
Life Science Journal | Year: 2013

The nervus oculomotorius leaves the cranial cavity through its own foramen and divides into rami superior and inferior. It carries pure somatic motor fibres as well as parasympathetic one. The radcix ciliaris brevis is present and it is fused with the radix ciliaris longa forming a common ciliary root. The ciliary ganglion has sympathetic root. There is only one ciliary nerve arising from the ciliary ganglion. The nervus trochlearis passes outside the cranial cavity through its own foramen. It has no connection with the other cranial nerves. It carries pure somatic motor fibres. The nervus abducens leaves the cranial cavity through its own foramen dorsal to the lateral margin of the prootic bridge. It enters the posterior eye muscle canal (myodome) and it has no connection with the other cranial nerves.


Issa A.Z.,Cairo University | Mahgoub A.F.,Sert University
Life Science Journal | Year: 2013

The nervus trigeminus arises by one root. It gives off the nervus ophthalmicus r which has an intracranial profundal ganglion and leaves the cranial cavity through its owen foramen.It divides into the radix ciliaris longa and the truncus ciliaris. The nervus trigeminus leaves the cranial cavity through the prootic foramen together with the anterodorsal lateral line nerve. It enters the Gasserian ganglion which lies extracranially. The Gasserian ganglion receives also the ramus ophthalmicus superficialis lateralis. The later ganglion gives off the rami ophthalmici superficialis trigeminus and lateralis as one ramus dorsally and the maxillomandibular trunk ventrally.The ramus ophthalmicus superficialis V carrying the lateralis fibres enters the olfactory region passing through a depression in the dorsal edge of the sphenoseptal commissure. This ramus carries general somatic sensory fibres to the skin dorsal and anterior to the eyes and to that covering the olfactory capsule and special somatic sensory ones (lateralis fibres). There is a single constrictor dorsalis nerve (carries visceromotor fibres), which innervate the levator arcus palatini and the dilator opercularis muscles. The ramus maxillaris divided into dorsal and ventral divisions and anastomoses with the ramus palatinus of the nervus facialis. The ramus maxillaris carries general somatic sensory fibres to the skin and special ones (lateralis fibres) from the anterior lateral line nerve and visrosensory ones for the taste buds (from the nervus facialis). The ramus mandibularis V divides into ramus externus and ramus internus. It carries visceromotore fibres to the adductor mandibularis and the anterior and posterior intermandibularis muscles and general (to the skin and teeth) and special(to the lateral line neuromasts) somatic sensory fibres and special visrosensory ones to the taste buds at the most anterior part of lower lip and jaw.

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