Choi S.-J.,Seoul Womens University |
Choy J.-H.,Ewha Womans University
Nanomedicine | Year: 2011
Layered double hydroxides (LDHs), also known as anionic nanoclays or hydrotalcite-like compounds, have attracted a great deal of interest for their potential as delivery carriers. In this article, we describe the cellular uptake behaviors and uptake pathway of LDHs in vitro and in vivo, which can not only explain the mechanism by which high efficacy of biomolecules delivered through LDH nanocarriers could be obtained, but also provide novel strategies to enhance their delivery efficiency. Toxicological effects of LDHs in cell lines and in animal models are also present, aiming at providing critical information about their toxicity potential, which should be carefully considered for their biomedical application. Understanding the uptake behaviors, uptake mechanism and toxicity of LDHs in terms of dose-response relationship, diverse physicochemical properties and interaction with different biological systems is important to optimize delivery efficiency as well as biocompatibility. © 2011 Future Medicine Ltd.
Jeong T.,Seoul Womens University
Measurement: Journal of the International Measurement Confederation | Year: 2015
This paper describes the design process of the MEMS-based pressure sensor and analysis of circuit characteristics and parameters such as mechanical and electrical variation. Using the industry standard electrical and mechanical tools for design and analysis, in short duration low cost mechatronics equipment with improved accuracy and performance can be achieved. In this paper, piezoresistive material characteristics and theoretical signal conditioning analyses are also investigated for improving its performance. A newly proposed design technology for MEMS-based pressure sensors make a small circuit containing the electromagnetic component, transformer and analyzed for the said purpose. © 2014 Elsevier Ltd.
Yang C.S.,Rutgers University |
Hong J.,Seoul Womens University
Annual Review of Nutrition | Year: 2013
Tea, made from leaves of the plant Camellia sinensis, Theaceae, has been used by humans for thousands of years, first as a medicinal herb and then as a beverage that is consumed widely. For the past 25 years, tea has been studied extensively for its beneficial health effects, including prevention of cancer, reduction of body weight, alleviation of metabolic syndrome, prevention of cardiovascular diseases, and protection against neurodegenerative diseases. Whether these effects can be produced by tea at the levels commonly consumed by humans is an open question. This review examines these topics and elucidates the common mechanisms for these beneficial health effects. It also discusses other health effects and possible side effects of tea consumption. This article provides a critical assessment of the health effects of tea consumption and suggests new directions for research in this area. © 2013 by Annual Reviews. All rights reserved.
Palukaitis P.,Seoul Womens University
Molecular Plant-Microbe Interactions | Year: 2016
Satellite RNAs and satellite viruses are extraviral components that can affect either the pathogenicity, the accumulation, or both of their associated viruses while themselves being dependent on the associated viruses as helper viruses for their infection. Most of these satellite RNAs are noncoding RNAs, and in many cases, have been shown to alter the interaction of their helper viruses with their hosts. In only a few cases have the functions of these satellite RNAs in such interactions been studied in detail. In particular, work on the satellite RNAs of Cucumber mosaic virus and Turnip crinkle virus have provided novel insights into RNAs functioning as noncoding RNAs. These effects are described and potential roles for satellite RNAs in the processes involved in symptom intensification or attenuation are discussed. In most cases, models describing these roles involve some aspect of RNA silencing or its suppression, either directly or indirectly involving the particular satellite RNA. © 2016 The American Phytopathological Society.
Kim S.K.,Seoul Womens University
Arts in Psychotherapy | Year: 2013
The purpose of this study was to examine the effects of art therapy on healthy aging in older adults in terms of its promotion of well-being and a better quality of life. Few research studies have been conducted on the Korean American older adult population to investigate the effectiveness of art therapy. The present study was undertaken to quantitatively assess the effect of art therapy on this population using three standardized psychological instruments to measure the dependent variables of affect, anxiety, and self-esteem. This study showed positive results that support the hypothesis that the art therapy intervention with 50 Korean American older adults promoted healthy aging by reducing negative emotions, improving self-esteem, and decreasing anxiety. Large effect sizes indicated an 84.6% positive change in affect (. r=92) and a 70.6% positive change in state of anxiety (r=84) for participants in the art therapy intervention group over the control group. Moderate effect sizes of the art therapy intervention indicated positive changes in self-esteem and trait anxiety (r=75 and r=. 74, respectively). Therefore, art therapy sessions need to be designed for and applied to the older population, and they should target the cultivation of positive attitudes to improve self-esteem, and the elimination of negative emotions to promote emotional well-being. These factors encompass the promotion of better health for older individuals. © 2012 Elsevier Inc.