Concomitant confluent and reticulated papillomatosis and acanthosis nigricans in an obese girl with insulin resistance successfully treated with oral minocycline: Case report and published work review
Fukumoto T.,Kobe University |
Kozaru T.,Kobe University |
Sakaguchi M.,Sendai University |
Oka M.,Sendai University
Journal of Dermatology | Year: 2017
Concomitant confluent and reticulated papillomatosis (CRP) and acanthosis nigricans (AN) is rare. We present a case of concomitant CRP and obesity-associated AN in a 12-year-old obese Japanese girl. Curiously, oral minocycline therapy, which has been shown to be effective for CRP, was effective against both CRP and AN. Possible mechanisms by which minocycline could have improved skin lesions of CRP and obesity-associated AN are discussed. In addition, reports of concomitant CRP and obesity-associated AN are reviewed. CRP and obesity-associated AN share common clinicopathological features and some reports have described concomitant CRP and obesity-associated AN. Together with the observation that skin lesions of CRP and obesity-associated AN in the present case responded to oral minocycline therapy, these facts suggest a tight relationship or a common pathogenetic pathway between these pathologies. © 2017 Japanese Dermatological Association.
Miyanishi T.,Sendai University |
Endo S.,Sendai University |
Nagahara R.,National Institute of Fitness and Sports in Kanoya
Sports Biomechanics | Year: 2017
Base stealing is an important tactic for increasing the chance of scoring in baseball. This study aimed to compare the crossover step (CS) and jab step (JS) starts for base stealing start performance and to clarify the differences between CS and JS starts in terms of three-dimensional lower extremity joint kinetics. Twelve male baseball players performed CS and JS starts, during which their motion and the force they applied to the ground were simultaneously recorded using a motion-capture system and two force platforms. The results showed that the normalised average forward external power, the average forward–backward force exerted by the left leg, and the forward velocities of the whole body centre of gravity generated by both legs and the left leg were significantly higher for the JS start than for the CS start. Moreover, the positive work done by hip extension during the left leg push-off was two-times greater for the JS start than the CS start. In conclusion, this study has demonstrated that the jab step start may be the better technique for a base stealing start and that greater positive work produced by left hip extension is probably responsible for producing its larger forward ground reaction force. © 2017 Informa UK Limited, trading as Taylor & Francis Group
Oba T.,Nippon Telegraph and Telephone |
Oba T.,Sendai University |
Hori T.,Nippon Telegraph and Telephone |
Nakamura A.,Nippon Telegraph and Telephone |
Ito A.,Sendai University
IEEE Transactions on Audio, Speech and Language Processing | Year: 2012
Discriminative training has received a lot of attention from both the machine learning and speech recognition communities. The idea behind the discriminative approach is to construct a model that distinguishes correct samples from incorrect samples, while the conventional generative approach estimates the distributions of correct samples. We propose a novel discriminative training method and apply it to a language model for reranking speech recognition hypotheses. Our proposed method has round-robin duel discrimination (R2D2) criteria in which all the pairs of sentence hypotheses including pairs of incorrect sentences are distinguished from each other, taking their error rate into account. Since the objective function is convex, the global optimum can be found through a normal parameter estimation method such as the quasi-Newton method. Furthermore, the proposed method is an expansion of the global conditional log-linear model whose objective function corresponds to the conditional random fields. Our experimental results show that R2D2 outperforms conventional methods in many situations, including different languages, different feature constructions and different difficulties. © 2011 IEEE.
Tomata Y.,Sendai University |
Kakizaki M.,Sendai University |
Suzuki Y.,Sendai Shirayuri Women's College |
Tsuji I.,Sendai University
Journal of Epidemiology and Community Health | Year: 2014
Objective: To examine the hypothesis that disability prevalence has increased to a greater degree in the areas severely affected by the earthquake and tsunami of 11 March 2011 than in other areas. Methods: Longitudinal analysis using public statistics data from the Ministry of Health, Labour and Welfare in Japan. The analysis included 1549 municipalities covered by the Long-term Care Insurance (LTCI) system. 'Disaster areas' were defined as three prefectures (Iwate, Miyagi, Fukushima). The outcome measure was the number of aged people (≥65 years) with LTCI disability certification. Rates of change in disability prevalence from February 2011 to February 2012 were used as the primary outcome variable, and were compared by analysis of covariance between 'Coastal disaster areas', 'Inland disaster areas' and 'Non-disaster areas'. Results: Regarding disability prevalence at all levels, the mean value of the increase rate in Coastal disaster areas (7.1%) was higher than in Inland disaster areas (3.7%) and Non-disaster areas (2.8%) (p<0.001). Conclusions: The areas that were severely affected by the earthquake and tsunami had a significantly higher increase in disability prevalence during the 1 year after the earthquake disaster than other areas.
Sanchez J.M.,University of Texas at Austin |
Mohri T.,Sendai University
Computational Materials Science | Year: 2016
In this paper we obtain approximate solutions to the Cluster Variation free energy by carrying out a cluster expansion of the probabilities appearing in the free energy functional in terms of concentration-dependent basis functions, and by truncating the expansion at different cluster levels prior to minimization. We show that a significant improvement over the Bragg-Williams approximation can be achieved by truncating the expansion of the cluster probabilities at relatively small clusters, thus dramatically reducing the number of equations that need to be solved in order to minimize the free energy. Furthermore, the free energy functional in the Cluster Variation Method offers a well-controlled case study to infer the effects of truncating the expansion of the energy of alloy formation in the commonly used Cluster Expansion method, versus the effects of truncating the expansion when using a concentration-dependent basis. Examples of the approach are given for simple Ising models for fcc- and bcc-based prototype alloy systems. © 2016 Elsevier B.V.
Li H.,Sendai University |
Li H.,Lanzhou University |
Yin S.,Sendai University |
Wang Y.,Lanzhou University |
Sato T.,Sendai University
Journal of the American Ceramic Society | Year: 2013
This work focused on the synthesis of high-activity strontium titanate (SrTiO3) photocatalysts through an environmentally friendly process. A high energy-efficient microwave-assisted hydrothermal method was employed to prepare Fe-loaded SrTiO3 that consisted of small particles around 50 nm in diameter. To achieve the effective assistance of long-lasting fluorescence, the obtained Fe-loaded SrTiO3 samples were coupled with CaAl2O4:(Eu, Nd). The photocatalytic activities were evaluated by the photo-decomposition of NO. Fe loaded SrTiO3 showed high photocatalytic activities not only under visible light irradiation but also in the dark with fluorescence assistance. © 2013 The American Ceramic Society.
Li H.,Sendai University |
Yin S.,Sendai University |
Sato T.,Sendai University
Applied Catalysis B: Environmental | Year: 2011
The systematic experiments of photocatalytic degradation of NO gas were carried out by using novel composites containing TiO2-xNy loaded on a long afterglow phosphor, CaAl2O4:(Eu,Nd). The composites were prepared in a sequence of procedures, which involved reactions of TiCl3 and hexamethylenetetramine (HMT) mixed solution at 190°C for 2h to precipitate nano-size TiO2-xNy particles, followed by mixing the TiO2-xNy with a micro-size CaAl2O4:(Eu,Nd) particles by a soft planetary ball milling to yield CaAl2O4:(Eu,Nd)/TiO2-xNy composites. Photocatalytic degradation of NO was monitored both under UV light irradiation and in the dark after turning off the light. The composite displayed excellent photocatalytic activity under UV-light irradiation as well as persistent activity after turning off light. A promising strategy involves coupling of visible light responsive photocatalyst with long afterglow phosphor was established. It is a new concept for the photocatalyst synthesis implying a possibility of a novel persistent active photocatalytic system. © 2011 Elsevier B.V.
Guo C.,Sendai University |
Yin S.,Sendai University |
Zhang P.,Sendai University |
Yan M.,Sendai University |
And 3 more authors.
Journal of Materials Chemistry | Year: 2010
Nanosize homogenous rod-like tungsten bronze CsxWO3 with excellent NIR shielding ability was successfully synthesized by a novel and facile water controlled-release solvothermal process (WCRSP). © 2010 The Royal Society of Chemistry.
Aso Y.,Howard Hughes Medical Institute |
Hattori D.,Howard Hughes Medical Institute |
Yu Y.,Howard Hughes Medical Institute |
Johnston R.M.,Howard Hughes Medical Institute |
And 7 more authors.
eLife | Year: 2014
We identified the neurons comprising the Drosophila mushroom body (MB), an associative center in invertebrate brains, and provide a comprehensive map describing their potential connections. Each of the 21 MB output neuron (MBON) types elaborates segregated dendritic arbors along the parallel axons of ∼2000 Kenyon cells, forming 15 compartments that collectively tile the MB lobes. MBON axons project to five discrete neuropils outside of the MB and three MBON types form a feedforward network in the lobes. Each of the 20 dopaminergic neuron (DAN) types projects axons to one, or at most two, of the MBON compartments. Convergence of DAN axons on compartmentalized Kenyon cell-MBON synapses creates a highly ordered unit that can support learning to impose valence on sensory representations. The elucidation of the complement of neurons of the MB provides a comprehensive anatomical substrate from which one can infer a functional logic of associative olfactory learning and memory.
Yoshimura A.,Sendai University |
Komoto Y.,National Hospital Organization Kurihama Medical and Addiction Center Yokosuka |
Higuchi S.,National Hospital Organization Kurihama Medical and Addiction Center Yokosuka
Alcoholism: Clinical and Experimental Research | Year: 2016
Background: The classification of alcohol use disorder has changed over the past century. Now, the conceptualization of alcohol dependence is still controversial. Accumulating evidence has shown the reliability and validity for the diagnosis of alcohol dependence in the ICD-10 and DSM-IV. However, the meaning and association of the respective diagnostic items, which are descriptive of representative symptoms, have hardly been examined. The core symptom of substance use disorder has been debated in various situations, but has never been elucidated logically. Methods: We consecutively registered 192 patients with alcohol-related problems who visited our hospital for the first time during a certain period. The relations and principal components among the checked items of the ICD-10 diagnostic criteria were examined statistically. Results: Three diagnostic items in the ICD-10 were strongly correlated with each other and were thought to form the core symptoms of alcohol dependence: "strong desire," "difficulties in controlling," and "neglect of pleasures." One major physical phenomenon, "withdrawal," seemed to complement the core symptoms in the diagnosis of alcohol dependence. Another physical phenomenon, "tolerance," was demonstrated to be a relatively independent item. The principal component analysis also demonstrated that the diagnostic item "difficulties in controlling" had the maximum component loading value, followed by 2 items, "neglect of pleasures" and "strong desire." Conclusions: The core symptomatic elements in the diagnosis of alcohol dependence were statistically suggested in this study. Knowledge of the relations and components among the diagnostic items of alcohol dependence might also be applicable to other forms of substance use dependence and behavioral addiction. © 2016 Research Society on Alcoholism.