Funaishikawa, Japan
Funaishikawa, Japan

Seijoh University is a public university in Tōkai, Aichi, Japan. The university opened in April 2002 but the predecessor of the school, Ishida Education Group, was founded in 1941. Wikipedia.

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Miwa K.,Nagoya Gakuin University | Nomura J.,Seijoh University | Takakuwa S.,Chuo University
Proceedings - Winter Simulation Conference | Year: 2017

A systematic procedure for module-based modeling is designed and proposed to simulate of any multistage manufacturing flow type system adopting a dual-card kanban system with a delivery cycle. First, a functional analysis was performed to present kanban flows in exactly the same fashion in a simulation model as they actually appear in a real manufacturing system. One shipping area module, the required number of parts store modules, and one supplier center module were used to develop a designated simulation. Proposed modules have focused dialogs, animation, and modeling functionality. In addition, a procedure to obtain the necessity minimum number of kanbans to achieve no stock-out events is proposed. Then, a numerical example is shown to apply the proposed procedure. © 2016 IEEE.


Ueki S.,Toyota National College of Technology | Kawasaki H.,Gifu University | Ito S.,Gifu University | Nishimoto Y.,Gifu University | And 5 more authors.
IEEE/ASME Transactions on Mechatronics | Year: 2012

This paper presents a virtual reality (VR)-enhanced new hand rehabilitation support system that enables patients to exercise alone. This system features a multi-degrees-of-freedom (DOF) motion assistance robot, a VR interface for patients, and a symmetrical master-slave motion assistance training strategy called self-motion control, in which the stroke patients healthy hand on the master side creates the assistance motion for the impaired hand on the slave side. To assist in performing the fine exercise motions needed for functional recovery of the impaired hand, the robot was constructed in an exoskeleton with 18 DOFs, to assist finger and thumb independent motions such as flexion/extension and abduction/adduction, thumb opposability, and hand-wrist coordinated motions. To enhance the effectiveness of the exercises, audio-visual instructions of each training motion using VR technology were designed with the input of clinician researchers. Experimental results from healthy subjects and patients show sufficient performance in the range of motion of the robot as well as sufficient assistance forces. © 2011 IEEE.


Ota S.,Seijoh University | Ueda M.,Syutaikai Hospital | Aimoto K.,National Center for Geriatrics and Gerontology | Suzuki Y.,National Center for Geriatrics and Gerontology | Sigward S.M.,University of Southern California
Knee | Year: 2014

Background: Restrictions in range of ankle dorsiflexion (DF) motion can persist following ankle injuries. Ankle DF is necessary during terminal stance of gait, and its restricted range may affect knee joint kinematics and kinetics. The purpose of this study was to investigate the acute influence of varied levels of restricted ankle DF on knee joint sagittal and frontal plane kinematics and kinetics during gait. Methods: Thirty healthy volunteers walked with a custom-designed ankle brace that restricted ankle DF. Kinematics and kinetics were collected using a 7-camera motion analysis system and two force plates. Ankle dorsiflexion was restricted in 10-degree increments, allowing for four conditions: Free, light (LR), moderate (MR) and severe restriction (SR). Knee angles and moments were measured during terminal stance. Results: Real peak ankle DF for Free, LR, MR, and SR were 13.7. ±. 4.8°, 11.6. ±. 5.0°, 7.5. ±. 5.3°, and 4.2. ±. 7.2°, respectively. Peak knee extension angles under the same conditions were -. 6.7. ±. 6.7°, -. 5.4. ±. 6.4°, -. 2.5. ±. 7.5°, and 0.6. ±. 7.8°, respectively, and the peak knee varus moment was 0.48. ±. 0.17. Nm/kg, 0.47. ±. 0.17. Nm/kg, 0.53. ±. 0.20. Nm/kg, and 0.57. ±. 0.20. Nm/kg. The knee varus moment was significantly increased from MR condition with an 8-degree restriction in ankle DF. Conclusion: Knee joint kinematics and kinetics in the sagittal and frontal planes were affected by reduced ankle DF during terminal stance of gait. Differences were observed with restriction in ankle DF range of approximately 8°. Level of evidence: level III. © 2014 Elsevier B.V.


Hayashi H.,Seijoh University | Hayashi H.,Nagoya University | Shimizu H.,Nagoya University
Journal of Hand Therapy | Year: 2013

Study design: Bench research. Introduction: Although information on the range of motion (ROM) required to perform activities is important when setting ROM goals to enable patients to engage in them, there are few studies reporting the required ROM of fingers. Purpose of the study: To analyze the range of joint motion required of the finger MCP joint to perform activities and to compare the maximum flexion and maximum extension angle required of the finger MCP joints in the individual fingers. Methods: We used an electrogoniometer to measure the ROM of four finger MCP joints in the dominant hand in healthy adults (n = 20) performing 19 activities. Finger MCP joint angles were analyzed throughout each of the 19 tasks. Results: The mean ROM of finger MCP joints of the index, middle, ring, and little fingers required to perform all 19 activities ranged from -10 to 60°, -10 to 75°, -10 to 80°, and -10 to 85°, respectively. The mean maximum flexion angle of the finger MCP joints gradually increased as the finger MCP joints were compared moving from the radial to the ulnar side. Conclusion: The data obtained in this study on MCP joint motions that are required to perform activities may be beneficial in setting ROM goals for patients with finger MCP joint impairment. Level of evidence: NA. © 2013 Hanley & Belfus, an imprint of Elsevier Inc. All rights reserved.


The senescence-accelerated mouse strain P6 (SAMP6) is a model of senile osteoporosis, which possesses many features of senile osteoporosis in humans. So far, little is known about the systemic bone microstructural changes that occur at the cervical, thoracic, and lumbar vertebrae. In this study, we therefore investigated segmental variations of vertebral trabecular bone mineral density (BMD) and three-dimensional microstructure in SAMP6 and the normal control mouse (SAMR1) at 12. months of age using quantitative micro computed tomography (micro-CT) and image analysis software. The vertebral height and vertebral cross-sectional area (CSA) increased, while vertebral trabecular BMD and trabecular bone volume fraction (BV/TV) decreased from the cervical to lumbar spine both in SAMR1 and SAMP6. As compared with SAMR1, the thoracic vertebral CSA had a tendency to be low and the lumbar vertebral CSA was significantly declined in SAMP6. The vertebral trabecular BMD, BV/TV, trabecular thickness (Tb.Th), and trabecular number (Tb.N) significantly decreased in cervical, thoracic and lumbar spine of SAMP6. Trabecular bone pattern factor (TBPf) was higher at the lumbar spine and the structure model index (SMI) of the lower thoracic and lumbar spine was higher in SAMP6. These results indicate that vertebral trabecular bone microstructures are remarkably heterogeneous throughout the spine in both SAMR1 and SAMP6. The decrease of vertebral trabecular bone density in SAMP6 advanced faster caudally than cranially within the spine, similar phenomena were observed in humans. These findings highlight the relevance of SAMP6 for studies of vertebral fragility associated with senile osteoporosis. © 2012 Elsevier Inc.


Furuzawa M.,Asahi University | Chen H.,Gifu University | Fujiwara S.,Asahi University | Yamada K.,Nagoya Women's University | Kubo K.-Y.,Seijoh University
Experimental Gerontology | Year: 2014

Chronic mild stress is a risk factor for osteoporosis and chewing inhibits the stress response. We examined the effect of chewing on chronic stress-induced bone loss and bone microstructural deterioration in mice. The senescence-accelerated mouse strain P8 (SAMP8) was randomly divided into control, stress, and stress with chewing groups of fifteen animals each. Mice in the stress and stress with chewing groups were placed in a ventilated restraint tube for 60. minutes, twice a day for 4. weeks. The restrained mice were simultaneously subjected daily to one of the following stressors: water immersion, physical shaking and flashing lights. Mice in the stress with chewing group were allowed to chew a wooden stick during the experimental period. After the experiment, the bone response was evaluated using quantitative micro computed tomography, bone histomorphometry, and biochemical markers. Exposure of SAMP8 mice to chronic stress resulted in significant increase of the blood corticosterone and noradrenaline levels, and adrenal weight. The bone resorption was activated and the bone formation was suppressed. Trabecular bone volume and trabecular number were decreased in both the vertebra and distal femur of the stress group. Chewing under chronic stress prevented the increase in the blood corticosterone and noradrenaline levels, attenuated the reduced bone formation and increased bone resorption, improved the trabecular bone loss and bone microstructural deterioration induced by chronic mild stress. These findings indicate that chewing can ameliorate chronic stress-induced bone loss in SAMP8 mice. Thus, chewing may represent a useful method preventing and/or treating chronic stress-related osteoporosis. © 2014 Elsevier Inc.


Chen H.,Gifu University | Washimi Y.,Aichi University | Kubo K.-Y.,Seijoh University | Onozuka M.,Kanagawa Dental College
Histology and Histopathology | Year: 2011

Despite increasing interest in age- and gender-related bone alterations, data on trabecular microstructure at the proximal tibia are scarce. The aim of this study was to identify trabecular microstructural change at the human proximal tibia with age and gender, using micro-computed tomography (micro-CT) and scanning electron microscopy (SEM). Fifty-six proximal tibias from 28 Japanese men and women (57-98 years of age) were used in this study. The subjects were chosen to give an even age and gender distribution. Both women and men were divided into three age groups, middle (57- 68 years), old (72-82 years) and elderly (87-98 years) groups. The trabecular bone specimens from the medial compartment of the proximal tibial metaphysis were examined. Trabecular bone mineral density (BMD), bone volume fraction (BV/TV) and trabecular thickness (Tb.Th) decreased between the middle-aged and elderly groups similarly in women and men. However, trabecular number (Tb.N) decreased by 13% between the middle-aged and elderly groups in women and nearly double that in men. As compared with women, men had higher BV/TV and lower trabecular separation (Tb.Sp) in the old age and elderly groups, and higher Tb.N and connectivity density (Conn.D) in the elderly group. Increased trabecular resorbing surfaces, perforated or disconnected trabeculae and microcallus formations were observed with age. These findings indicate that both BMD and BV/TV decreased at the proximal tibia with age similarly for women and men, but significant differences between women and men were observed for some microstructural parameters. These findings illustrate potential mechanisms underlying osteoporotic proximal tibial fracture.


Chen H.,Gifu University | Kubo K.-Y.,Seijoh University
World Journal of Orthopaedics | Year: 2014

Osteoporosis is a common metabolic skeletal disorder characterized by decreased bone mass and deteriorated bone structure, leading to increased susceptibility to fractures. With aging population, osteoporotic fractures are of global health and socioeconomic importance. The three-dimensional microstructural information of the common osteoporosis-related fracture sites, including vertebra, femoral neck and distal radius, is a key for fully understanding osteoporosis pathogenesis and predicting the fracture risk. Low vertebral bone mineral density (BMD) is correlated with increased fracture of the spine. Vertebral BMD decreases from cervical to lumbar spine, with the lowest BMD at the third lumbar vertebra. Trabecular bone mass of the vertebrae is much lower than that of the peripheral bone. Cancellous bone of the vertebral body has a complex heterogeneous three-dimensional microstructure, with lower bone volume in the central and anterior superior regions. Trabecular bone quality is a key element to maintain the vertebral strength. The increased fragility of osteoporotic femoral neck is attributed to low cancellous bone volume and high compact porosity. Compared with age-matched controls, increased cortical porosity is observed at the femoral neck in osteoporotic fracture patients. Distal radius demonstrates spatial inhomogeneous characteristic in cortical microstructure. The medial region of the distal radius displays the highest cortical porosity compared with the lateral, anterior and posterior regions. Bone strength of the distal radius is mainly determined by cortical porosity, which deteriorates with advancing age. © 2014 Baishideng Publishing Group Inc.


Chen H.,Gifu University | Iinuma M.,Asahi University | Onozuka M.,Nippon Sport Science University | Kubo K.-Y.,Seijoh University
International Journal of Medical Sciences | Year: 2015

Mastication (chewing) is important not only for food intake, but also for preserving and promoting the general health. Recent studies have showed that mastication helps to maintain cognitive functions in the hippocampus, a central nervous system region vital for spatial memory and learning. The purpose of this paper is to review the recent progress of the association between mastication and the hippocampus-dependent cognitive function. There are multiple neural circuits connecting the masticatory organs and the hippocampus. Both animal and human studies indicated that cognitive functioning is influenced by mastication. Masticatory dysfunction is associated with the hippocampal morphological impairments and the hippocampus-dependent spatial memory deficits, especially in elderly. Mastication is an effective behavior for maintaining the hippocampus-dependent cognitive performance, which deteriorates with aging. Therefore, chewing may represent a useful approach in preserving and promoting the hippocampus-dependent cognitive function in older people. We also discussed several possible mechanisms involved in the interaction between mastication and the hippocampal neurogenesis and the future directions for this unique fascinating research. © 2015 Ivyspring International Publisher.


This study aimed to identify psychosocial risk factors involved in the progression of senility associated with dementia, and clarify activities that may prevent such progression. In 2003, as a part of the Aichi Gerontological Evaluation Study Project, a self-completion postal questionnaire survey was conducted among elderly persons aged 65 years or older not under the Certification of Eligibility for Long-Term Care (hereafter, Certification); (response rate: 49.4%). Among the respondents, 9,720 subjects (4,614 males, 5,106 females; average age 72.8 years, range +/- 6.0), whose gender and age were confirmed and who could handle all ADLs independently, were selected for the three-year longitudinal study. The end point of the study was Certification in the second appraisal, through categorization under the ADL Independence Assessment Criteria for the Elderly with Dementia Rank II. Predictive variables used in the study were: health behavior, psychological/ cognitive factors, recreational/social activities, TMIG Index of Competence, and social class. Recreational activities were divided into eight types: sports, culture, music, creative activities, gardening, radio and TV, sightseeing, and investment/gambling. The Cox proportional-hazards regression model was used to determine an age-adjusted hazard ratio (HR) for each in both males and females. Subsequently, those factors with a significant HR were used as predictive variables in stepwise regression for further clarification. At the end of the 3-year study, the number of subjects who received Certification associated with dementia was 330 (139 males, 191 females); 9,390 were otherwise categorized. The percentage of Certified subjects was 1.13 per year. The following predictive factors showed significant HRs: in both the male and female groups, self-awareness of forgetfulness (male 1.69, female 2.59) and 4 points or less in instrumental independence scores (male 1.80, female 2.23); in the males, living alone (2.39), subjective poor health (2.04), no work (1.80) 3 points or less in intellectual activity score (2.13), and no gardening (1.99); and in the female group, no sports (1.92) The study found that the occurrence of Certification associated with dementia is less in those who are enjoying good psychosocial/daily life conditions, in males involved in gardening, and in females involved in sports. Thus the study suggests the importance of focusing on these factors, more so than health behavior, in terms of progressive dementia prevention.

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