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Juyal D.,Veer Chandra Singh Garhwali Government Medical science and Research Institute | Thawani V.,Veer Chandra Singh Garhwali Government Medical science and Research Institute | Thaledi S.,Seema Dental College and Hospital
North American Journal of Medical Sciences | Year: 2015

Background: Publishing research papers for academic fraternity has become important for career advancement and promotion. Number of publications in peer reviewed journals and subsequent citations are recognized as measures of scientifi c success. Non-publishing academicians and researchers are invisible to the scientifi c community. Discussion: With pressure to publish, misconduct has crept into scientifi c writing with the result that research misconduct, plagiarism, misappropriation of intellectual property, and substantial unattributed textual copying of another’s publication have become common. The Offi ce of Research Integrity, USA, defi nes research misconduct as “fabrication, falsifi cation or plagiarism in proposing, performing or reviewing research, or in reporting research results.” Although plagiarism is diffi cult to defi ne in few words, it can be viewed as the stealing of another person’s ideas, methods, results, or words without giving proper attribution. The Offi ce of Research Integrity defi nes plagiarism as being “theft or misappropriation of intellectual property and the substantial unattributed textual copying of another’s work.” Plagiarism is one of the most vehemently derided breaches of research integrity as it undermines the original and honest contribution to an existing body of knowledge. Conclusion: Plagiarism has many forms viz. blatant plagiarism, technical plagiarism, patchwork plagiarism, and self-plagiarism. In any form, the plagiarism is a threat to the research integrity and is unacceptable. We do need to detect such acts and effectively prosecute the offenders. © 2015, North American Journal of Medical Sciences. All rights reserved.

Juyal D.,Veer Chandra Singh Garhwali Government Medical science and Research Institute | Thawani V.,Shri Guru Ram Rai Institute of Medical and Health science | Thaledi S.,Seema Dental College and Hospital | Joshi M.,Veer Chandra Singh Garhwali Government Medical science and Research Institute
Journal of Traditional and Complementary Medicine | Year: 2014

Taxus wallichiana Zucc., known as Himalayan yew, belongs to the family Taxaceae. It is a medium-sized, temperate, Himalayan forest tree of medicinal importance. In India, this evergreen tree is found at altitudes between 1800 and 3300 m above mean sea level (MSL). It has been used by the native populations for treating common cold, cough, fever, and pain. Its uses are described in Ayurveda and Unani medicine. It received attention recently as its leaves and bark were found to be the prime source of taxol, a potent anticancer drug. It possesses many other biological activities also. We focus on its importance in traditional medicine for its multiple medicinal properties. Copyright © 2014 Committee on Chinese Medicine and Pharmacy, Taiwan.

Shaikh S.,ACPM Dental College | Ravenndranath R.,Government Dental College | Banerjee M.,Rajiv Gandhi Center for Biotechnology | Jahgirdar P.,Seema Dental College and Hospital
Medicina Oral, Patologia Oral y Cirugia Bucal | Year: 2012

Objectives: Orofacial clefts are major human birth defects with complex etiology. Previous studies have proposed Transforming growth factor - beta 3 (TGF-β3) gene as a key player in contributing to non-syndromic cleft lip and palate, however none of the studies have yet included Indian population. Hence this study was designed to detect TGF-β3 gene polymorphism in nonsyndromic cleft lip and palate patients from Indian population which is genetically distinct from previously studied populations. Study Design: Peripheral blood samples of forty non-syndromic cleft lip and palate patients and forty unaffected individuals were collected for a case - control study design. Ethical clearance from the institutional review board and informed consent from all subjects was obtained. DNA extracted from the cases and controls was amplified using polymerase chain reaction (PCR) with TGF-β3 specific primers. The obtained fragments were sequenced and TGF-β3 gene polymorphisms were assessed based on the number of CA repeats. Results: Chi -square test was used to compare the case and control groups. Results showed a significant difference in the number of CA repeats between the case and the control groups (p=0.01). Conclusion: This study confirms the crucial role of TGF-β3 in the fusion of palatal shelves during development and further, provides novel evidence of TGF-β3 gene polymorphism in the etiology of nonsyndromic cleft lip and palate in Indian subpopulation. © Medicina Oral S. L.

Jahagirdar P.B.,Seema Dental College and Hospital
Journal of the Indian Society of Pedodontics and Preventive Dentistry | Year: 2011

Tuberous sclerosis or tuberous sclerosis complex is a dominantly inherited neurocutaneous disorder that variably affects the brain, skin, kidneys, heart, and other organs. Diagnosis of tuberous sclerosis becomes difficult in the young individuals with subtle changes. At this point, a careful inquiry and examination of the accessible signs and symptoms can errand a possible diagnosis. We hereby report such a rare case of tuberous sclerosis in 14-year-old boy, which was diagnosed in a novel approach.

Mrinalini M.,Sri Guru Ram Rai Institute of Medical science and Research | Chetan C.,Seema Dental College and Hospital
Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology | Year: 2015

True generalized macrodontia in young children is an extremely rare occurrence reported in patients afflicted by a very uncommon disorder called Rabson-Mendenhall syndrome. This syndrome is an autosomal recessive disorder characterized by insulin resistance. A case with all the classical features of this syndrome i.e. insulin-resistant diabetes, acanthosis nigricans, hypertrichosis, deficiency of subcutaneous fat, growth retardation, coarse senile facies, large ears, macroglossia, furrowed tongue and dental prematurity along with marked generalized macrodontia of grotesque proportions in a 10-year-old girl is reported here, and the literature available is briefly reviewed. © 2014 Asian AOMS, ASOMP, JSOP, JSOMS, JSOM, and JAMI.

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