Forsberg D.,Linkoping University |
Forsberg D.,Sectra Inc.
Lecture Notes in Engineering and Computer Science
Segmentation of the vertebrae in the spine is of relevance to many medical applications. To this end, the 2nd MICCAI workshop on Computational Methods and Clinical Applications for Spine Imaging organized a segmentation challenge. This paper briefly presents one of the participating methods along with achieved results. The employed method is based upon atlas-based segmentation, where a number of atlases of the spine are registered to the target data set. The labels of the deformed atlases are combined using label fusion to obtain the final segmentation of the target data set. An average DICE score of 0.94 ± 0.03 was achieved on the training data set. © Springer International Publishing Switzerland 2015. Source
Eklund A.,Virginia Polytechnic Institute and State University |
Dufort P.,University of Toronto |
Forsberg D.,Linkoping University |
Forsberg D.,Sectra Inc. |
And 2 more authors.
Medical Image Analysis
Graphics processing units (GPUs) are used today in a wide range of applications, mainly because they can dramatically accelerate parallel computing, are affordable and energy efficient. In the field of medical imaging, GPUs are in some cases crucial for enabling practical use of computationally demanding algorithms. This review presents the past and present work on GPU accelerated medical image processing, and is meant to serve as an overview and introduction to existing GPU implementations. The review covers GPU acceleration of basic image processing operations (filtering, interpolation, histogram estimation and distance transforms), the most commonly used algorithms in medical imaging (image registration, image segmentation and image denoising) and algorithms that are specific to individual modalities (CT, PET, SPECT, MRI, fMRI, DTI, ultrasound, optical imaging and microscopy). The review ends by highlighting some future possibilities and challenges. © 2013 Elsevier B.V. Source
Sjolund J.,Elekta Instrument AB |
Sjolund J.,Linkoping University |
Forsberg D.,Linkoping University |
Forsberg D.,Sectra Inc. |
And 2 more authors.
Physics in Medicine and Biology
Radiotherapy planning and attenuation correction of PET images require simulation of radiation transport. The necessary physical properties are typically derived from computed tomography (CT) images, but in some cases, including stereotactic neurosurgery and combined PET/MR imaging, only magnetic resonance (MR) images are available. With these applications in mind, we describe how a realistic, patient-specific, pseudo-CT of the head can be derived from anatomical MR images. We refer to the method as atlas-based regression, because of its similarity to atlas-based segmentation. Given a target MR and an atlas database comprising MR and CT pairs, atlas-based regression works by registering each atlas MR to the target MR, applying the resulting displacement fields to the corresponding atlas CTs and, finally, fusing the deformed atlas CTs into a single pseudo-CT. We use a deformable registration algorithm known as the Morphon and augment it with a certainty mask that allows a tailoring of the influence certain regions are allowed to have on the registration. Moreover, we propose a novel method of fusion, wherein the collection of deformed CTs is iteratively registered to their joint mean and find that the resulting mean CT becomes more similar to the target CT. However, the voxelwise median provided even better results; at least as good as earlier work that required special MR imaging techniques. This makes atlas-based regression a good candidate for clinical use. © 2015 Institute of Physics and Engineering in Medicine. Source
Wevers-de Boer K.V.C.,Leiden University |
Heimans L.,Leiden University |
Visser K.,Leiden University |
Kolvesten J.,Sectra Inc. |
And 10 more authors.
Annals of the Rheumatic Diseases
Aim: To assess whether in early (rheumatoid) arthritis (RA) patients, metacarpal bone mineral density (BMD) loss after 4 months predicts radiological progression after 1 year of antirheumatic treatment. Methods: Metacarpal BMD was measured 4 monthly during the first year by digital X-ray radiogrammetry (DXR-BMD) in patients participating in the IMPROVED study, a clinical trial in 610 patients with recent onset RA (2010 criteria) or undifferentiated arthritis, treated according to a remission (disease activity score<1.6) steered strategy. With Sharp/van der Heijde progression ≤0.5 points after 1 year (yes/no) as dependent variable, univariate and multivariate logistic regression analyses were performed. Results: Of 428 patients with DXR-BMD results and progression scores available, 28 (7%) had radiological progression after 1 year. Independent predictors for radiological progression were presence of baseline erosions (OR (95% CI) 6.5 (1.7 to 25)) and early DXR-BMD loss (OR (95% CI) 1.5 (1.1 to 2.0)). In 366 (86%) patients without baseline erosions, early DXR-BMD loss was the only independent predictor of progression (OR (95% CI) 2.0 (1.4 to 2.9)). Conclusions: In early RA patients, metacarpal BMD loss after 4 months of treatment is an independent predictor of radiological progression after 1 year. In patients without baseline erosions, early metacarpal BMD loss is the main predictor of radiological progression. © 2015, BMJ Publishing Group. All rights reserved. Source
Sectra Inc. | Date: 2016-01-12
Scientific, photographic, cinematographic and optical apparatus and instruments for weighing, measuring and signaling; apparatus for recording, transmission, reproduction, storing and processing of data, information, sound and images; electrical apparatus and instrument for treatment, transmission and communication of signals; electronic encryption units; device for receiving, processing and transmission of data, information, sound and images; computers; lap top computers; central processing units processors; peripherals adapted for use with computers; touch sensitive electronic screens; telephones; mobile phones; printers; magnetic and optical data storage drives; encoded magnetic cards containing programming for encryption, decryption and authentication of data, information, sound and images; SD-cards containing programming for encryption, decryption and authentication of data, information, sound and images; SD-cards for computers and telephones containing programming for encryption, decryption and authentication of data, information, sound and images; data communications apparatus, information terminals, transaction terminals; communication and radio apparatus for encryption, decryption and authentication of data, information, sound and images; plotters; bar code readers; computer programs for digital management, processing, analysis, diagnosis, examination, reference, storage, archiving and communication of medical images; computer programs for collecting, storing and monitoring radiation doses in the medical field; computer operating system software; computer programs for recording, transmission, reproduction, storing and processing of data, information, sound and images; computer programs for medical purposes; computer programs for patient data; computer programs and computer hardware for medical image processing, managing of images, archiving and communication of medical images; computer programs and computer hardware for 3D visualization of images; computer programs for education, namely, educational software in the medical field, medical technology, telecommunication and secure communication fields; computer programs for pre-surgical planning; computer programs for provision of information through computer networks, document free solutions, workflow monitoring, schedules, statistics, invoicing; computer programs for time reservations and time planning; computer programs for encryption, decryption and authentication; electronic publications, namely, books, catalogues, magazines, manuals and handbooks in the medical, medical technology, telecommunication and secure communication fields; electronic components and replacement parts for computers, data communications apparatus; electronic encryption units, telephones, mobile phones, touch sensitive electronic screens, communication and radio apparatus. Medical imaging apparatus; computer screens and touch sensitive electronic screens incorporated as a part of and used in association with medical diagnosis apparatus; image management system for medical purpose, namely, for processing, analysis, diagnosis, examination, reference, storage, archiving and communication of medical images. Encrypted electronic transmission of data, information, sound and images; providing access to telecommunication networks; computer transmission services; computer aided transmission of data, information, sound and images; digital transmission and broadcasting services; electronic bulletin board services; IP-communication services (Internet Protocol); telecommunication gateway services; communications by computer terminals; video broadcasting and transmission services via the Internet, featuring films and movies; electronic transmission of messages; telecommunication, namely, providing access to distributed databases; providing user access to global computer networks; providing access to databases; providing access to electronic bulletin boards; transmission of database information via telecommunication networks; communication services, namely, transmission of data, information, sound, images and computer programs, all via wire and/or wireless provision access to networks that covers a large area, local networks and internet; rental of phones; secured data, information, sound and image transmission services. Industrial analysis and research services; design and development of computer hardware and computer programs; software as a service SaaS; consultancy services relating to information technology; installation of computer programs; design and development of networks; design and development of networks for encryption, decryption and authentication; consultancy in the field of computer systems and computer programs; computer programming; repair of computer programs maintenance, updating; provision of computer programs; rental of computers; rental of computer programs; server hosting; rental of web servers; consultancy in the field of technical and scientific information, including computer technology, telecommunication, electronics and medical technology; encryption, decryption and authentication of data, information, sound and images; interconnection of computer units; technical images analysis services; electronic (computer) data storage; software as a service SaaS in the field of recording, transmission, reproduction, storing and processing of data, information, sound and images and within the fields encryption, decryption and authentication and within the field for medical purposes; computerized storing of business information. Medical services; medical online services; analysis and examination of medical images; online services for analysis and examination of medical images; consultancy services in the field of health care; X-ray services; digital image processing for medical purposes; medical screening.