Section of Diabetes

Pisa, Italy

Section of Diabetes

Pisa, Italy
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Bertolotto A.,Section of Diabetes | Volpe L.,Section of Diabetes | Calianno A.,University of Pisa | Pugliese M.C.,University of Pisa | And 7 more authors.
Journal of Maternal-Fetal and Neonatal Medicine | Year: 2010

Objectives.We designed this study to assess the potential effects of physical activity and dietary habits on glucose tolerance during pregnancy. Methods.This is an observational study involving 268 women who underwent a 50-g oral glucose challenge test (GCT) at 27±6.9 week of gestation. Plasma glucose level at 1-h GCT≥140 mg/dl was used to define abnormal glucose tolerance (AGT). Physical activity was evaluated using the short form of the International Physical Activity Questionnaire (IPAQ), while for dietary habits we used a food frequency questionnaire linked to a computerised program. Results.One hundred five women had AGT (AGT) and 163 had normal glucose tolerance (AGT-). There was no difference between the two groups in demographic and clinical data, with the exception of pre-pregnancy BMI and weight gain both higher in AGT women. Also, all parameters referring to physical activity energy and diet (Kcal and diet components) were not statistically different between the two groups. After a multivariate analysis, only pre-pregnancy BMI (F-value 9.264, p=0.002) remained an independent predictor of 1-h plasma glucose. Conclusions.Our study suggests that high pre-pregnancy BMI confers a substantially high risk of AGT, independently of lifestyle during pregnancy. © 2010 Informa UK, Ltd.


PubMed | Section of Diabetes.
Type: Journal Article | Journal: The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians | Year: 2010

We designed this study to assess the potential effects of physical activity and dietary habits on glucose tolerance during pregnancy.This is an observational study involving 268 women who underwent a 50-g oral glucose challenge test (GCT) at 276.9 week of gestation. Plasma glucose level at 1-h GCT 140 mg/dl was used to define abnormal glucose tolerance (AGT). Physical activity was evaluated using the short form of the International Physical Activity Questionnaire (IPAQ), while for dietary habits we used a food frequency questionnaire linked to a computerised program.One hundred five women had AGT (AGT+) and 163 had normal glucose tolerance (AGT). There was no difference between the two groups in demographic and clinical data, with the exception of pre-pregnancy BMI and weight gain both higher in AGT+ women. Also, all parameters referring to physical activity energy and diet (Kcal and diet components) were not statistically different between the two groups. After a multivariate analysis, only pre-pregnancy BMI (F-value 9.264, p=0.002) remained an independent predictor of 1-h plasma glucose.Our study suggests that high pre-pregnancy BMI confers a substantially high risk of AGT, independently of lifestyle during pregnancy.

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