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Arguello E.J.,Simon Bolivar University of Venezuela | Silva R.J.,Secretaria de Educacion Superior | Silva R.J.,University of Guayaquil | Huerta M.K.,Secretaria de Educacion Superior | And 3 more authors.
BioMedical Engineering Online | Year: 2015

This commentary is intended to find possible explanations for the low impact of computational modeling on pain research. We discuss the main strategies that have been used in building computational models for the study of pain. The analysis suggests that traditional models lack biological plausibility at some levels, they do not provide clinically relevant results, and they cannot capture the stochastic character of neural dynamics. On this basis, we provide some suggestions that may be useful in building computational models of pain with a wider range of applications. © Argüello et al.

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