Yu M.,Huazhong University of Science and Technology |
Yu M.,Key Laboratory of Education |
Huang Q.,Second Peoples Hospital of Nanning |
Jin R.,Huazhong University of Science and Technology |
And 6 more authors.
Proceedings of the ACM Symposium on Applied Computing | Year: 2012
Lesion segmentation plays an important role in medical image processing and analysis. There exist several successful dynamic programming (DP) based segmentation methods for general images. In those methods, the gradient is used as an important factor in the cost function to attract the contours to the boundaries. Since medical images have their characteristics such as low contrast, blurred edges and high noises, the gradient operator cannot work well enough to achieve a satisfactory performance for boundary detection. We define the local intra-class variance and combine it with the dynamic programming method to replace the traditional gradient operation. Experiments on synthetic and X-ray images are carried out and the results are compared with Canny and fast multilevel fuzzy edge detection (FMFED) algorithms. It is demonstrated that the proposed method performs better on medical images with low contrast, blurred edges and high noises. In addition, 483 regions of interest of mammograms randomly extracted from DDSM of the University of South Florida are used to compare our proposed method with the plane-fitting and dynamic programming method (PFDP), and the normalized cut segmentation method (Ncut). The results demonstrate that our method is more accurate and robust than PFDP and Ncut. © 2012 ACM.
Wang B.-Q.,Second Peoples Hospital Of Nanning
Chinese Journal of Tissue Engineering Research | Year: 2015
BACKGROUND: Traditional therapies for multiple rib fractures include extra-thoracic pressure dressing and rib fixation, but have no ideal outcomes because of a higher pain and complication incidence. OBJECTIVE: To discuss the clinical efficacy of internal fixation of TiNi encircling compressive connector on multiple rib fractures and to analyzes its security. METHODS: Ninety patients with multiple rib fractures were selected to be studied, and they were divided into treatment group (45 patients were subject to internal fixation of TiNi encircling compressive connector) and control group (45 patients were subject to internal fixation with Kirschner wire. Surgical time, mechanical ventilation time, length of stay, duration of analgesic drug, and complication incidence were compared between two groups. Visual analog scale scores were measured before and after internal fixation. RESULTS AND CONCLUSION: The visual analog scale scores were significantly decreased in the both two groups at 12, 24, 48 hours after internal fixation (P < 0.05), moreover, the treatment group had lower scores on the visual analog scale than the control group at 12, 24, 48 hours after internal fixation (P < 0.05). Compared with the control group, the surgical time, mechanical ventilation time, length of stay, duration of analgesic drug, and complication incidence were all lower in the treatment group (P < 0.05). These findings indicate that the internal fixation of TiNi encircling compressive connector is effective in the treatment of multiple rib fractures, which is characterized as simple operation, small injury, high stability, low complication incidence and good histocompatibility. © 2015, Journal of Clinical Rehabilitative Tissue Engineering Research. All rights reserved.
Huang K.,Second Peoples Hospital of Nanning |
Du G.,Second Peoples Hospital of Nanning |
Li L.,Second Peoples Hospital of Nanning |
Liang H.,Second Peoples Hospital of Nanning |
Zhang B.,Second Peoples Hospital of Nanning
Biomarkers | Year: 2012
Context: Chemerin has been implicated to be correlated with inflammation. Objective: This study aims to determine the association of chemerin levels in serum and synovial fluid (SF) with the disease severity of patients with knee Osteoarthritis (OA). Methods: 124 patients with knee OA and 76 healthy controls were enrolled in this study. Results: Chemerin levels in serum were significant higher with regard to paired SF. Chemerin levles in SF of knee OA patients were correlated with disease severity evaluated by KL grading criteria. Conclusion: Chemerin levels may be involved in the pathophysiology of the development and progression of OA. © 2012 Informa UK, Ltd.