Time filter

Source Type

Wei R.-Q.,Second Peoples Hospital of Foshan City | Deng R.,Second Peoples Hospital of Foshan City | Huang K.,Second Peoples Hospital of Foshan City
Chinese Journal of Tissue Engineering Research | Year: 2014

BACKGROUND: Achilles tendon is placed in superficial position, and blood supply is few offered. Open injury leads to severe contamination, which is difficult to remove by complete debridement. Following the repair surgery, the infection, local skin defects and tendon exposure occur, change of dressing obtains unsatisfactory outcome. OBJECTIVE: To investigate the clinical application of vacuum sealing drainage technique combined with reversed sural neurovascular pedicle flap to treat post-operative infection and skin of Achilles tendon. METHODS: From 2009 to 2012, 13 patients with post-operative infection and skin of Achilles tendon were selected from the Second People's Hospital of Foshan City, China, including 8 males and 5 females. The age of the involved patients was 25-65 years old. The accompanied soft tissue defects after ankle were ranged 4 cm×5 cm to 7 cm×6 cm, and repaired with repeated debridement and vacuum sealing drainage technique, until the wound granulation tissue was clean and the infection was controlled. The skin defects were repaired by reversed sural neurovascular pedicle flap. The healing of the wound was observed during follow-ups. RESULTS AND CONCLUSION: All the patients were followed for 9-14 months. All the flaps survived completely in 13 patients, with good appearance, blood supply and texture. No secondary necrosis and infection was found. According to the AOFAS evaluation, the excellent rate of ankle joint function was 90% at post-operative 6 months. The wound infection can be effectively controlled by vacuum sealing drainage. The reversed sural neurovascular pedicle flap could provide a good covering for the exposed tendon and a flap with fine appearance, blood supply, texture and elasticity for soft tissue defects. The recovery of ankle joint functions is excellent, without local cicatricial contracture.


Liao Q.-L.,Guangdong Medical College | Zhao J.-Q.,Second Peoples Hospital of Foshan City | Zhu X.-J.,Second Peoples Hospital of Foshan City | Wang K.-N.,Guangdong Medical College | And 5 more authors.
Tumor | Year: 2015

Objective: To explore the value of diffusion-weighted imaging (DWI) combined with conventional magnetic resonance imaging (MRI) in diagnostic staging and the decision of treatment method in patients with cervical cancer. Methods: The data of DWI MRI from 42 patients pathologically confirmed with cervical cancer were retrospectively analyzed. The apparent diffusion coeffcient (ADC) and exponential ADC (eADC) values were measured. The ADC and eADC values were compared according to different pathologic types and stages of cervical cancer, and between the cervical cancer and normal cervix. The diagnostic accuracy of DWI combined with conventional MRI for pathologic staging was examined. The ADC and eADC values were compared between radiochemotherapy group and the surgery group. Results: The cervical cancer demonstrated high signal intensity on DWI, whereas the normal cervix showed no obviously abnormal signal intensity. The mean ADC value of 42 patients with cervical cancer was lower than that of normal cervix (P = 0.000); the mean ADC value of cervical squamous-cell cancer was lower than that of adenocarcinoma (P = 0.036); the mean ADC value of radiochemotherapy group before treatment was lower than that of surgery group (P = 0.000), whereas the eADC value was higher than that of surgery group (P = 0.000). There were no significant differences in mean ADC and eADC values among different pathologic stages of cervival cancer (all P values < 0.05). The diagnostic accuracy of conventional MRI and DWI combined with conventional MRI for pathologic staging were 92.9% (39/42) and 95.2% (40/42), respectively (Kappa = 0.903 5 and 0.935 8, respectively; P < 0.01). Conclusion: DWI combined with MRI exerts a high value in diagnostic staging of cervical cancer. The ADC value can be used as reference in selection of therapeutic methods for stage II B cervical cancer. © 2015 by TUMOR All rights reserved.


Wang F.,Second Peoples Hospital of Foshan City | Wang J.,Huazhong University of Science and Technology | Gong S.,Tongren University
Cell Biochemistry and Biophysics | Year: 2013

We evaluated the histologic and histochemical (succinate dehydrogenase, SDH) changes in cochleas of guinea pigs after non-focused ultrasound (NFU) irradiation. For this purpose, the cochleas of 50 guinea pigs (both ears in Groups 1-10) were irradiated at 2.5-8.0 MHz NFU for 6 h and the histologic/histochemical changes were determined. Our data show that after NFU irradiation for 6 h, no histological changes were observed in the cochleas by silver staining and scanning electron microscopic examination; however, the SDH activity of the basilar membranes and stria vascularises at the corresponding position decreased significantly. The SDH values of basilar membranes and stria vascularis were higher at 8 h than at 30 min after the NFU irradiation. SDH activity of the outer hair cells presented more declination than that of the inner hair cells. It was, therefore, concluded that a certain dosage of NFU irradiation at various frequencies could lead to metabolic changes in the basilar membrane and stria vascularis at different areas of cochlea. Moreover, these changes were found to be reversible or partially reversible. These changes also suggest that the cochlear hair cells located at different areas might be related to ultrasonic perception. © 2012 Springer Science+Business Media New York.


Wei R.,Second Peoples Hospital of Foshan City
Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery | Year: 2012

To investigate the method and the effectiveness of open pelvic fractures associated with perineal injury. Between August 2000 and July 2010, 16 cases of open pelvic fractures associated with perineal injury were treated. There were 12 males and 4 females with an average age of 41 years (range, 17-69 years). Injury was caused by traffic accidents in 9 cases, by falling from height in 6 cases, and by crushing in 1 case. The mean time between injury and admission was 8 minutes (range, 5-20 minutes). According to Tile classification, 2 cases were rated as type A, 6 as type B, and 8 as type C. The wound size ranged from 5 cm x 3 cm to 15 cm x 12 cm. The perineal injured location included intraperitoneal rectal injury in 2 cases and extraperitoneal anorectal injury in 14 cases. The average injury severity score (ISS) was 29 (range, 25-48). The main treatments included emergency resuscitation, colostomy, external fixation of fractures, repeated debridement with pulsatile irrigation followed by intravenous antibiotics, and vacuum sealing drainage (VSD). In 5 deaths, 3 cases died of hemorrhagic shock and 2 cases died of multiple system organ failure within 4 days of admission. The other 11 cases were followed up 6-46 months (mean, 14 months). The X-ray films showed that bone union was achieved after 2-4 months of operation. Infection in varying degree occurred at perineal wounds; second stage healing of wounds was achieved in 10 cases after debridement and VSD treatment, and wound healed in 1 case after gracilis muscle flap repair. No anal incontinence occurred in the patients having anorectal injury during follow-up. For patients with perineal injury and open pelvic fractures, the following treatments should be carried out so as to obtain good effectiveness: early anti-shock, protection of important organ function, treatment of complications, late resistance to infection and stability restoration of the pelvic ring, functional repair and reconstruction of rectum and anal canal and urinary tract.


PubMed | Second Peoples Hospital of Foshan City
Type: Journal Article | Journal: Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery | Year: 2012

To investigate the method and the effectiveness of open pelvic fractures associated with perineal injury.Between August 2000 and July 2010, 16 cases of open pelvic fractures associated with perineal injury were treated. There were 12 males and 4 females with an average age of 41 years (range, 17-69 years). Injury was caused by traffic accidents in 9 cases, by falling from height in 6 cases, and by crushing in 1 case. The mean time between injury and admission was 8 minutes (range, 5-20 minutes). According to Tile classification, 2 cases were rated as type A, 6 as type B, and 8 as type C. The wound size ranged from 5 cm x 3 cm to 15 cm x 12 cm. The perineal injured location included intraperitoneal rectal injury in 2 cases and extraperitoneal anorectal injury in 14 cases. The average injury severity score (ISS) was 29 (range, 25-48). The main treatments included emergency resuscitation, colostomy, external fixation of fractures, repeated debridement with pulsatile irrigation followed by intravenous antibiotics, and vacuum sealing drainage (VSD).In 5 deaths, 3 cases died of hemorrhagic shock and 2 cases died of multiple system organ failure within 4 days of admission. The other 11 cases were followed up 6-46 months (mean, 14 months). The X-ray films showed that bone union was achieved after 2-4 months of operation. Infection in varying degree occurred at perineal wounds; second stage healing of wounds was achieved in 10 cases after debridement and VSD treatment, and wound healed in 1 case after gracilis muscle flap repair. No anal incontinence occurred in the patients having anorectal injury during follow-up.For patients with perineal injury and open pelvic fractures, the following treatments should be carried out so as to obtain good effectiveness: early anti-shock, protection of important organ function, treatment of complications, late resistance to infection and stability restoration of the pelvic ring, functional repair and reconstruction of rectum and anal canal and urinary tract.

Loading Second Peoples Hospital of Foshan City collaborators
Loading Second Peoples Hospital of Foshan City collaborators