Second Hospital of Ningbo City

Ningbo, China

Second Hospital of Ningbo City

Ningbo, China
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Gao D.,Zhejiang University | Gao D.,Zhejiang Chinese Medical University | Cui Y.,Zhejiang Chinese Medical University | Wu J.,Zhejiang Chinese Medical University | And 2 more authors.
Journal of Traditional Chinese Medicine | Year: 2014

OBJECTIVE: To summarize the treatment of oligoasthenospermatism (OAS) with Traditional Chinese Medicine (TCM).METHODS: The literature describing OAS treatment with TCM in the past 4 years was searched. Three studies were reviewed, evaluated, and summarized. The etiology and pathogenesis, pattern differentiation, medicine administration, and combination of TCM with Western Medicine were all examined.RESULTS: TCM had an advantage in treating OAS and had fewer adverse events than conventional treatments.CONCLUSION: Although TCM has an advantage in treating OAS and fewer adverse events, the efficacy of TCM and modern medicine on OAS is unsatisfactory. © 2014 JTCM. All rights reserved.


Yang T.,Second Hospital of Ningbo City | He G.,Second Hospital of Ningbo City | Fu Q.,Second Hospital of Ningbo City | Yu J.,Second Hospital of Ningbo City | And 2 more authors.
Chinese Journal of Clinical Oncology | Year: 2011

Objective: To investigate the correlation of GST-π and Topo II expression with the chemosensitivity of breast cancer cells in vitro. Methods: ATP-tumor chemosensitivity assay (ATP-TCA) was used to determine the effect of 4 single chemotherapeutics [Epirubicin (EPI), Paclitaxel (PTX), Taxotere (TXT), and Gemcitabine (GEM)] and 2 combined regimens [ Epirubicin + Taxotere (EPI + TXT ), Cyclophosphamide + Epirubicin + 5-Fluorouracil (CEF)] of in virro breast cancer cells from 45 breast cancer patients. Expression of GST-π and Topo II was examined by immunohistrochemistry. Results: ATP-TCA showed that the inhibitory rates of EPI, PTX, TXT and GFM for breast cancer cell growth were 62.2 %, 35.6 %, 8.9 %, and 15.6 %, respectively. The inhibitory rates of EPI+TXT and CEF were 77.8 % and 73.3 %, respectively, higher than those of PTX, TXT, and GEM (P < 0.01). Immunohistochemistry showed that the expression rates of GST-π and Topo II were 44.4 % (20/45) and 62.2 % (28/45), respectively. EPI, EPI+TXT and CEF showed higher inhibitory rate in cases with Topo II expression or in cases without GST-π expression (P< 0.01). Conclusion: ATP-TCA combined with detection of GST-π and Topo II expression can be used to screen effective therapeutics against breast cancer.


Hong F.-Y.,Second Hospital of Ningbo City | Yan D.-X.,Second Hospital of Ningbo City | Chen P.,Second Hospital of Ningbo City
World Chinese Journal of Digestology | Year: 2015

AIM: To assess the clinical effect of implementation of nursing pathway in patients undergoing subtotal gastrectomy. METHODS: From June 2011 to July 2014, 270 patients undergoing subtotal gastrectomy were included in the study. They were divided into two groups: an experimental group (n = 135) and a control group (n = 135). The control group received routine nursing care, and clinical nursing pathway was implemented in the experimental group. The visual analogue score (VAS) score, nursing effect, satisfaction to nursing care and the awareness of health knowledge were observed and compared. RESULTS: VAS score showed no significant difference at 6 h after operation between the two groups (P > 0.05), but was significantly lower in the experimental group than in the control group at 12, 24 and 72 h (P < 0.05). Near the discharge, VAS score showed no significant difference between the two groups (P > 0.05). The total effective rate of nursing care was significantly higher in the experimental group (127/135, 94.07%) than in the control group (116/135, 85.93%) (P < 0.05). The rate of satisfaction to nursing care was significantly higher in the experimental group (127/135, 94.07%) than in the control group (116/135, 85.93%) (P < 0.05). The rate of awareness of health knowledge was also significantly higher in the experimental group (116/135, 85.93%) than in the control group (98/135, 72.59%) (P < 0.05). CONCLUSION: The implementation of clinical nursing pathway in patients undergoing subtotal gastrectomy can effectively relieve postoperative pain, improve nursing efficiency and satisfaction, and make the patients acquire more health knowledge. © 2015 Baishideng Publishing Group Inc. All rights reserved.

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