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Medellín, Colombia

Toro-Lezcano M.M.,University of Antioquia | Molina Saldarriaga F.,Pontifical Bolivarian University | Soto A.F.,Seccion de Microbiologia Dinamica | Diaz Granados Cuenca L.,Pontifical Bolivarian University | Guerra Villafane A.,University of Antioquia
Infectio | Year: 2015

Invasive aspergilosis (IA) is caused by Aspergillum particles inhalation such as mildew and yeast. They live in the soil as a natural habitat. This infection has been described in patients with a bone marrow transplant and serious neutropenia (<500 mm3). Inward patients of intensive care unit (ICU) can be also susceptible to them, and even more with risk factors associated such as chronic obstructive pulmonary disease (COPD), liver cirrhosis, autoimmune diseases with inmunosupressor therapy and solid organ transplantation, where mortality can reach 80% of cases. A case of IA in a man of 56 years old is described. He had smoking history without previous spirometric assessment. The patient developed IA during stay at the intensive care unit. Aspergillus septate hiphae were observed in the biopsy at the carina's ulcer. Galactomannan assay was positive in bronchioalvelar fluid. The patient had good clinical response to treatment with Voriconazole. © 2014 ACIN. Published by Elsevier España, S.L.U. All rights reserved. Source

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