Seccion de Endocrinologia y Nutricion

Arroyomolinos de León, Spain

Seccion de Endocrinologia y Nutricion

Arroyomolinos de León, Spain
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Lopez Gomez J.J.,Seccion de Endocrinologia y Nutricion | Ballesteros Pomar M.D.,Seccion de Endocrinologia y Nutricion | Vazquez Sanchez F.,Seccion de Neurologia | Vidal Casariego A.,Seccion de Endocrinologia y Nutricion | And 2 more authors.
Nutricion Hospitalaria | Year: 2011

Introduction: Malnutrition affects morbidity and mortality of patients with ALS. The nutrition unit should evaluate these patients early and regularly providing the necessary steps in the evolution of the disease. Methods: A retrospective cohort study in which we analyzed 46 patients diagnosed with ALS, 21 of them received nutritional therapy. We studied age, mode of onset, date of entry into a nutritional protocol, placement of PEG and survival. We performed a test of Breslow comparing patients who were at nutritional protocol with those not receiving nutritional support, and those who received early nutritional therapy with those with delayed nutrition. Results: There was an increase in median survival for patients in nutritional therapy in bulbar ALS (452 vs 55 days) and in spinal ALS (1,798 vs 357 days) (p = 0.002). The median delay in the initiation of nutritional therapy in spinal ALS was 557 days while in bulbar ALS was 230 days. The survival in the spinal ALS of those who entered into nutritional protocol before the median survival was 325 days to 181 days (p = 0.09) while in bulbar ALS those who entered before had a median survival of 435 days to 177 days (p = 0.38). Conclusions: The entry of patients with ALS in a nutritional protocol increases survival. There is an advantage in the evolution of patients with early nutritional treatment.


Calleja Fernandez A.,University of León | Munoz Weigand C.,University of León | Ballesteros Pomar M.,Seccion de Endocrinologia y Nutricion | Vidal Casariego A.,Seccion de Endocrinologia y Nutricion | And 4 more authors.
Nutricion Hospitalaria | Year: 2011

Background: The establishment of healthy eating habits in children at school and in family life is very important for preventing obesity in children. Aims: To know the habits of late-breakfast in a scholar population, the prevalence of overweight and obesity, and establish healthy dietary habits through the late-breakfast. Methods: A prospective interventional study was performed in a school group. Children from 10 to 13 yearsold were included. The study had three phases: pre-intervention (anthropometric assessment and questionnaire of late-breakfast frequency), intervention (parents and teachers received information about "the importance of proper nutrition in school" focused on the transcendence of a healthy and balanced diet that includes a suitable late-breakfast every day at school, and the students received the late-breakfast during two weeks that included milk, fruit and a traditional sandwich), and post-intervention (questionnaire of late-breakfast frequency). Results: Frequency of overweight was 10.6% and obesity 2.6%. After the intervention the proportion of children who had late-breakfast increased by 9.2%, and the kind of food which they ate changed. Conclusion: Dietary habits can be modified in a scholar population with an easy nutritional intervention.


Huidobro Fernandez B.,Hospital General Universitario Gregorio Maranon | Lopez Gomez J.J.,Seccion de Endocrinologia Y Nutricion | Huerta Aragones J.,Hospital General Universitario Gregorio Maranon | Salinero Paniagua E.,Hospital General Universitario Gregorio Maranon | Rodriguez Arnao M.D.,Hospital General Universitario Gregorio Maranon
Acta Pediatrica Espanola | Year: 2011

Endogenous Cushing's syndrome is rare endocrine disorders in pediatric age whose most common cause are the pituitary tumors producers of adrenocorticotropin (ACTH) (Cushing's syndrome, CS). This disease must be suspected in any children with unjustified weight gain associated with a decrease in the speed of growth. The first therapeutic option in the CS is the transsphenoidal adenomectomy, followed by radiotherapy if CS persists. After the treatment pituitary disorders can be associated which will need a substitutive therapy, growth hormone deficit can cause an inadequate catch-up growth in children. We report the case of a nearly 11 years-old girl with unjustified weight gain, growth stagnation, signs of virilization and proximal myopathy. Through hormonal determinations was confirmed an ACTH-dependent hypercortisolism was confirmed. The cranial MRI showed a pituitary micro adenoma that was removed through transsphenoidal adenomectomy with clinical and analytic remission. Before surgery, ketoconazole was used in order to control hypercortisolism. There were no signs of relapse four years later.


Pomar M.D.B.,Seccion de Endocrinologia y Nutricion | Casariego A.V.,Seccion de Endocrinologia y Nutricion | Fernandez A.C.,Seccion de Endocrinologia y Nutricion | Gomez J.J.L.,Seccion de Endocrinologia y Nutricion | And 2 more authors.
Nutricion Hospitalaria | Year: 2010

Inflammatory bowel disease is an entity with not well-known pathogenesis, and important nutritional and metabolic implications because of the high prevalence of malnutrition, the possible implication of dietary factors in its pathogenesis and because of the hypothesis that nutritional intervention could be a primary treatment for the disease. Some nutrients could induce a low antigenic stimuli, regulate inflammatory and immunological responses and stimulate intestinal mucosal trophism. Present available evidence supports enteral nutrition in Crohn's disease as a primary treatment if treatment with steroids is not possible (failure or contraindication) (grade of recommendation A) or either combined treatment with drugs in malnourished patients or those with inflammatory bowel stenosis. In those patients with sustained clinical remission, no benefit of either enteral nutrition or supplements in the absence of nutritional deficits has been shown. Elemental or modified formula (glutamine, omega 3 fatty acids) could not be recommended. In ulcerative colitis, nutritional influence over the activity of the disease has not been shown, although there are some promising results regarding enteric coated W3 fatty acids and a possible role for probiotics. In the treatment and prevention of pouchitis, there could be a role for probiotics (VSL#3). Nutritional treatment should be considered an integral component in the Management of patients with inflammatory bowel disease.


Vidal Casariego A.,Seccion de Endocrinologia Y Nutricion | Calleja Fernandez A.,Seccion de Endocrinologia Y Nutricion | Ballesteros Pomar M.D.,Seccion de Endocrinologia Y Nutricion | Lopez Gomez J.J.,Seccion de Endocrinologia Y Nutricion | Cano Rodriguez I.,Seccion de Endocrinologia Y Nutricion
Revista Espanola de Obesidad | Year: 2010

Rationale: Obesity and smoking can increase cardiovascular risk. The aim of this study is to find out the prevalence of smoking in obese people and the influence of smoking in cardiovascular risk. Methods: Cross-sectional study that included 126 patients, who were asked about tobacco consumption. Dependence was measured with Fagerström's test and motivation to give up smoking with Richmond's test. Cardiovascular risk was estimated using the DORICA score. Results: In the evaluated sample 22% of patients were smokers and 20,6% ex-smokers. Smoking was more frequent among female < 35 yr than in the same population group, and was associated to lower HDL cholesterol levels. The 40,7% of smokers had a high or very-high dependence and 74,1% had a low motivation. Cardiovascular risk was higher among smokers than among no-smokers [6,2 (8) % vs. 4 (8,5) %; p= 0,72], and it was significantly reduced when smoking was eliminated [6,2 (8) % a 3,5 (5,1 ) %; p< 0,001]. Conclusions: Tobacco consumption is more frequent among young female obese patients. Smoking is a very common risk factor among obese patients that should be evaluated and treated in the medical office.


PubMed | Seccion de Endocrinologia y Nutricion
Type: Case Reports | Journal: Nutricion hospitalaria | Year: 2010

We present the case of a male patient suffering from a primary amyloidosis and a nephrotic syndrome who came to dietotherapy clinic. In the first visit we made a nutritional record including an anthropometric evaluation, body composition, biochemistry, and food intake. The patient had an excess of body water, proteinuria, low plasma protein, albumin, prealbumin and HDL cholesterol levels, and high concentrations of total cholesterol, LDL and triglycerides. The consumption of protein and sodium was higher than the recommendation. An individualized diet was made. Six months later, his weight and the excess of body water decreased, but the fat free mass remained unchanged. The levels of albumin and prealbumin increased, the proteinuria decreased. Total cholesterol, LDL and triglycerides decreased until normal levels. Dietetary treatment in nephrotic syndrome is effective to decrease proteinuria, improve cholesterol and triglycerides levels, and to prevent malnutrition.


PubMed | Seccion de Endocrinologia y Nutricion
Type: Journal Article | Journal: Nutricion hospitalaria | Year: 2011

Malnutrition affects morbidity and mortality of patients with ALS. The nutrition unit should evaluate these patients early and regularly providing the necessary steps in the evolution of the disease.A retrospective cohort study in which we analyzed 46 patients diagnosed with ALS, 21 of them received nutritional therapy. We studied age, mode of onset, date of entry into a nutritional protocol, placement of PEG and survival. We performed a test of Breslow comparing patients who were at nutritional protocol with those not receiving nutritional support, and those who received early nutritional therapy with those with delayed nutrition.There was an increase in median survival for patients in nutritional therapy in bulbar ALS (452 vs 55 days) and in spinal ALS (1,798 vs 357 days) (p = 0.002). The median delay in the initiation of nutritional therapy in spinal ALS was 557 days while in bulbar ALS was 230 days. The survival in the spinal ALS of those who entered into nutritional protocol before the median survival was 325 days to 181 days (p = 0.09) while in bulbar ALS those who entered before had a median survival of 435 days to 177 days (p = 0.38).The entry of patients with ALS in a nutritional protocol increases survival. There is an advantage in the evolution of patients with early nutritional treatment.

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