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Seattle, WA, United States

Seattle Pacific University is a Christian university of the liberal arts, science and professions, located at 3307 3rd Avenue W. on the north slope of Queen Anne Hill in Seattle, Washington, USA. It was founded in 1891 by the Oregon and Washington Conference of the Free Methodist Church as the Seattle Seminary. It became the Seattle Seminary and College in 1913, changed names again to Seattle Pacific College in 1915, and took its present name in 1977. Seattle Pacific University is a member of the Christian College Consortium. Wikipedia.

Grabow W.W.,Seattle Pacific University | Jaeger L.,University of California at Santa Barbara
Accounts of Chemical Research

ConspectusNanotechnology's central goal involves the direct control of matter at the molecular nanometer scale to build nanofactories, nanomachines, and other devices for potential applications including electronics, alternative fuels, and medicine. In this regard, the nascent use of nucleic acids as a material to coordinate the precise arrangements of specific molecules marked an important milestone in the relatively recent history of nanotechnology.While DNA served as the pioneer building material in nucleic acid nanotechnology, RNA continues to emerge as viable alternative material with its own distinct advantages for nanoconstruction. Several complementary assembly strategies have been used to build a diverse set of RNA nanostructures having unique structural attributes and the ability to self-assemble in a highly programmable and controlled manner. Of the different strategies, the architectonics approach uniquely endeavors to understand integrated structural RNA architectures through the arrangement of their characteristic structural building blocks. Viewed through this lens, it becomes apparent that nature routinely uses thermodynamically stable, recurrent modular motifs from natural RNA molecules to generate unique and more complex programmable structures. With the design principles found in natural structures, a number of synthetic RNAs have been constructed. The synthetic nanostructures constructed to date have provided, in addition to affording essential insights into RNA design, important platforms to characterize and validate the structural self-folding and assembly properties of RNA modules or building blocks. Furthermore, RNA nanoparticles have shown great promise for applications in nanomedicine and RNA-based therapeutics.Nevertheless, the synthetic RNA architectures achieved thus far consist largely of static, rigid particles that are still far from matching the structural and functional complexity of natural responsive structural elements such as the ribosome, large ribozymes, and riboswitches. Thus, the next step in synthetic RNA design will involve new ways to implement these same types of dynamic and responsive architectures into nanostructures functioning as real nanomachines in and outside the cell. RNA nanotechnology will likely garner broader utility and influence with a greater focus on the interplay between thermodynamic and kinetic influences on RNA self-assembly and using natural RNAs as guiding principles. © 2014 American Chemical Society. Source

Gritter K.,Seattle Pacific University
Reading Teacher

When students create personal connections with literature during whole-class discussion, they make sense both of text and of their life experiences. In this article, the author shares tips that help students make text-to-self, text-to-world, and text-to-text connections. She offers classroom examples to illustrate how conversations that encourage these connections can benefit reading comprehension. © 2011 International Reading Association, Inc. Source

Snedker K.A.,Seattle Pacific University
Crime and Delinquency

Research indicates that men and women commonly express different amounts of fear about crime. This article explores the sex difference in fear of crime levels by assessing differences in fear of crime in relation to urban environments. Using data from the Bureau of Justice Statistics Criminal Victimization and Perceptions of Community Safety, the present analysis employs multinomial logistic regressions to examine gradations in two measures of fear of crime. Some aspects of the neighborhood environment do differentially influence men and women’s fear of crime levels, including serious crime in the neighborhood, physical and social disorder. Findings highlight that women’s greater fear of crime is partially due to higher perceived risks through signals of neighborhood conditions. © 2011 SAGE Publications. Source

Nagy W.E.,Seattle Pacific University | Carlisle J.F.,University of Michigan | Goodwin A.P.,Vanderbilt University
Journal of Learning Disabilities

The purpose of this special issue of the Journal of Learning Disabilities is to bring to the attention of researchers and educators studies on morphology and literacy that either involve students with learning difficulties or have educational implications for teaching such students. In our introduction, we first provide background information about morphological knowledge and consider the role of morphology in literacy, focusing on findings that are relevant for instruction of students who struggle with reading and writing. Next we present an overview of the studies included in this issue, organized by current issues concerning the role of morphological knowledge in literacy. Collectively, the articles in this issue suggest that students with weaker literacy skills tend to lag behind their peers in morphological knowledge but that all students are likely to benefit from morphological instruction. Morphological interventions hold promise, especially for students who face challenges in language learning and literacy, but additional research is needed to provide a basis for informed decisions about the design of effective morphological interventions. © Hammill Institute on Disabilities 2013. Source

Cloud computing technologies, such as Google Docs and Microsoft Office Live, have the potential to enhance instructional methods predicated on constructivism and cooperative learning. Cloud-based application features like file sharing and online publishing are prompting departments of education across the nation to adopt these technologies. However, realizing the full potential of these tools necessitates that future educators develop an understanding of how they can be used. Strategies for integrating cloud-based applications are suggested and results from a case study involving graduate education students are presented. © 2012 Springer Science+Business Media, LLC. Source

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