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Dharwad, India

Shivakumar J.,Karnataka Institute of Medical science | Shenoy J.P.,Father Muller Medical College | Karne S.L.,SDMCMSH | Muniyappanavar N.S.,BRIMS
Research Journal of Pharmaceutical, Biological and Chemical Sciences | Year: 2013

The forced vital capacity (FVC) maneuver is central to a multitude of information about the functioning of the lungs. But for it serve this purpose proper performance of this complex maneuver is essential. Standards have been prescribed by various agencies to monitor the FVC maneuver, concentrating mainly on adults. Children in general find it difficult to satisfy these adult based standards, and especially the forced expiratory time (FET) criterion, which is a part of the end of test (EOT) criteria, is found to be most difficult to achieve. Technically acceptable FVC maneuvers obtained from 91 children yielded FET values which were analyzed and Pearson's correlation coefficients were derived with height, weight, age and body surface area (BSA). The children in the present study produced an average FET of 1.53s, and over the age, height and weight ranges FET exhibited a positive correlation. Hence adult based standards may not be achieved by children vis-à-vis FET, even though the curves obtained are technically acceptable as far as complete expiration is concerned.

Dixit U.R.,SDMCMSH | Bendigeri N.D.,K.B.N.I.M.S
Indian Journal of Community Health | Year: 2015

Background: AIDS has been killing large number of people. The rate of infection of young children is quite high yet they are the ones who are not proportionately covered under ART. Children are vulnerable to infections more compared to adults and if malnutrition co-exists it makes them more vulnerable. Aims and objectives: To assess the impact of ART treatment on immune status; to study the common opportunistic infections among the study group; to study the relationship between supplementary nutrition and opportunistic infection. Materials and methods: A secondary data was collected about 46 children. Informed consent was taken from the parents/ guardians. Children were suggested to eat one extra meal and ground nuts and one egg thrice weekly. Result: There was significant increase in the CD4 count in these children (p <0.01) and the occurrence of opportunistic infections reduced significantly in those taking supplementary nutrition (p<0.001). In terms of opportunistic infections, skin infections were more common followed by tuberculosis and diarrhea. Conclusion: Supplementary nutrition reduces the opportunistic infections and also improves the immunity. However, the study needs to be done with more sample size. © 2015, Indian Association of Preventive and Social Medicine. All rights reserved.

Srinivas K.K.,SDMCMSH | Uppin I.V.,JNMC | Nerle R.B.,JNMC
Journal of Clinical and Diagnostic Research | Year: 2011

Background: A study was conducted at the KLES hospital and MRC, Belgaum, for a period of 1 year from April 2004 to March 2005. Objectives: To compare the efficacy of open pyeloplasty and laparoscopic pyeloplasty in the treatment of primary ureteropelvic junction obstruction with regards to the subjective outcome. Materials and Methods: A total of 30 patients of congenital UPJO was evaluated and operated. All the 30 patients were randomized into two groups of 15 each. One group formed the open pyeloplasty group and the other formed the laparoscopic pyeloplasty group. All the patients were assessed for the subjective outcome post-operatively and all the patients were followed up for a minimum of 3 months. The results were analyzed by using the Student's paired and unpaired tests Results: The mean age group, the laterality of involvement of the kidney and the sex ratio were almost similar between the two groups. The pre-operative pain and the activity levels were almost similar and comparable between the 2 groups. But, there was a significant post-operative improvement in the pain and the activity level in each group. In our study, we found that the improvement in the pain and the activity level post-operatively was much better in the laparoscopic pyeloplasty group patients as compared to those in the open pyeloplasty group patients. The time period when oral feeds were started and the drain was removed, was slightly more in the laparoscopic group, owing to the transperitoneal approach. There was no conversion to open procedure done in any of laparoscopic cases. The postoperative cosmesis was better inthe laparoscopic pyeloplasty patients as compared to the open pyeloplasty patients. Conclusion: Our study was done on a small number of patients and the post-operative follow up was only for 3 months. It is difficult to draw conclusions from such a study. Hence, a large randomised controlled trial with a long period of follow up studies are needed to establish the role of laparoscopic pyeloplasty in the treatment of UPJ obstruction. The potential advantages of laparoscopic pyeloplasty over open pyeloplasty are decreased post-operative pain, a shorter period of hospitalisation, a short convalescence and improved cosmesis. Laparoscopic pyeloplasty is a technically challenging procedure and it is still in its infancy. It is being practised at only few medical centres around the world. With the recent technological advances, laparoscopic pyeloplasty has become a valid alternative to endoscopic pyelotomy and open pyeloplasty.

Anuradha S.K.,SDMCMSH | Surekha Y.A.,VIMS | Narayan S.,NHH | Sonth S.,SNMC | And 4 more authors.
Journal of Clinical and Diagnostic Research | Year: 2011

Background: A study was conducted in VIMS hospital at Bellary during the epidemic of August 2004 to July 2005. Objectives: To know the hospital based incidence of J.E and to study the age and sex pattern of the infection in the paediatric age group. Materials and Methods: 82 children admitted to the Paediatric ward, VIMS, Bellary with clinical diagnosis of acute viral encephalitis, during the epidemic of August 2004 to July 2005 were studied. After pooling the samples, they were subjected to J.E. MAC ELISA. Results: Out of 82 patients tested by J.E. MAC ELISA, 19 (24%) were positive for J.E. and 12 (14.63%) were positive for flaviviral infection. CSF was positive in all 19 cases with 100% positivity. Serum was positive in 10 cases with 15.87% positivity. This indicates that there are significant number of J.E. cases in Bellary emphasising the rampant nature and stressing the measures to be taken to overwhelm this devastating disease. Conclusion: The hospital based incidence of J.E. was found to be significant in the area of the study. The paediatric age group, between 4to 6 years was found to be most predisposed to J.E., probably because of low immunity in the age group. Male predominance was seen with male to female ratio of 1.42:1. Illiteracy, low socio economic status and living in unhygienic conditions near rice fields contributed to the high incidence of J.E. in and around Bellary. The serological results clearly establish the etiology. Isolation of JEV from specimens would have strengthened the diagnosis.

Mudaraddi R.,SDMCMSH | Ramesh,RIMS | Sameer,Sikkim Manipal IMS | Amareshwara M.,VIMS | And 3 more authors.
International Journal of Pharma and Bio Sciences | Year: 2011

The main aim of this study was to evaluate the role of Plasma advanced oxidation protein product (AOPP), protein carbonyl as indicator of oxidative stress and reduced glutathione, total thiols, albumin as antioxidant status among epileptics. 25 patients with history of epilepsy on treatment in the age group of 20-60 years were compared with 25 normal healthy controls of same age group. There was highly significant increase in AOPP (P=0.002) and protein carbonyl (p=0.001), with significantly decreased antioxidants such as reduced glutathione (p=0.007), total thiols (p=0.023) and albumin (0.01) were noted among epileptics when compared to healthy controls. From this study it could be concluded that increased oxidative stress and reduced antioxidants may be associated with pathophysiology of epilepsy.

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