SDM Medical College and Hospital

Dharwad, India

SDM Medical College and Hospital

Dharwad, India
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Haridas V.,SDM Medical College and Hospital | Haridas K.,Bangalore
Journal of Association of Physicians of India | Year: 2017

Granulomatosis with Polyangiitis (GPA) is a rare disease with varied clinical manifestations. We present a case of GPA which manifested initially with symptoms suggestive of meningeal tuberculosis. High index of suspicion and collective review of all clinical features helped in the correct diagnosis. Treatment of this case with rituximab provided significant symptomatic relief. © 2017, Journal of Association of Physicians of India. All rights reserved.

Kulkarni R.D.,Sdm Medical College And Hospital
Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology | Year: 2010

Introduction: Orofacial space infections are common presentations in maxillofacial clinics even in the post-antibiotic era. One of the main factors determining the spread of infection is the host defense mechanism. Diabetes is one of the most common systemic illness suppressing the immunity of an individual and increasing their susceptibility to infections. This study was carried out to compare the spaces involved, the severity of infection, the virulent organism, the efficacy of empirical antibiotics, the length of hospital stay, and the complications encountered in the management of maxillofacial space infection of odontogenic origin in diabetic patients as compared with nondiabetic patients. Methodology: A 4-year prospective study was carried out on patients with maxillofacial space infection of odontogenic origin. The patients were divided into 2 groups on the basis of presence or absence of diabetes. Results: A total of 111 patients were identified out of which 31 were diabetic. The organisms commonly isolated were Streptococcus species with submandibular space being the most common space involved in both the groups. The empirical antibiotic used was amoxicillin plus clavulanic acid combined with metrogyl in 70.27% cases. Conclusion: Streptococcus species is still the most common causative pathogen irrespective of the diabetic status of the patient. The same empirical antibiotic therapy of amoxicillin plus clavulanic acid combined with metrogyl along with hyperglycemia control and surgical drainage of infection yielded satisfactory resolution of infection in the diabetic patients as well. © 2010 Mosby, Inc.

Banakar B.F.,SDM Medical College and Hospital | Hiregoudar V.,SDM Medical College and Hospital
Journal of Neurosciences in Rural Practice | Year: 2017

Background: Cortical venous thrombosis (CVT) is a rare condition, compared to arterial stroke and often occurs in young individuals presenting with varying clinical features. Aim: The aim is to study clinical profile and assess the outcome and prognostic factors of CVT patients. Methodology: A case series study was done for 2 years. CVT cases confirmed by magnetic resonance imaging were included in this study. Clinical presentation and risk factors were noted then patients were assessed at the time of discharge for their physical and mental status. Modified Rankin scale was used to group patients, accordingly scores 0-2 were considered as good and 3-6 as poor outcome, respectively. Data were analyzed using Chi-square test to know the association between prognostic factors and outcome. Results: Out of 81 patients, more than half of the patients were in the age group of <35 years (55.6%), and majority of patients were females (79%). Most common symptom was headache (82.7%) and least was fever (14.8%). Superior sagittal sinus was most commonly involved (74.1%). Nearly half of the patients were in puerperal period (44.1%). Patients aged more than 35 years (odds ratio [OR]: 9.1, confidence interval [CI]: 4.463-19.750) presenting with symptoms such as fever (OR: 3.442, CI: 1.088-12.140), impaired consciousness (OR: 5.467, CI: 2.064-15.330) and having clinical signs such as coma (OR: 23.99, CI, 3.844-544.1), papilledema (OR: 25.15, CI: 7.565-101.5), and with focal neurological deficit (OR: 9.366, CI: 2.693-3.41) had statistically significant poor outcome. Conclusion: Females formed a major bulk of patients. Higher number patients showed poor outcome. Study showed association between age, headache, impaired consciousness, coma, papilledema, and neurological deficit to poor outcome. © 2017 Journal of Neurosciences in Rural Practice | Published by Wolters Kluwer - Medknow.

Sunilkumar P.D.,SDM Medical College and Hospital | Daddamani R.,SDM Medical College and Hospital
Indian Journal of Public Health Research and Development | Year: 2014

Sternoclavicular joint tuberculosis is very rare of all types of skeletal tuberculosis, hence it is likely to be missed most of the times and a high index of suspicion is required to diagnose it. If it is diagnosed in early stages then it can be managed conservatively with antitubercular drugs and surgery reserved only for advanced cases. Here we report two of such kind cases which were diagnosed with non invasive or semi invasive techniques and successfully treated with antitubercular drugs alone. © 2014 Indian Journal of Public Health Research and Development. All rights reserved.

Amane H.S.,SDM Medical College and Hospital | Burte N.P.,Mnr Medical College
Indian Journal of Pharmacology | Year: 2011

Objective: To compare the efficacy and safety profile of dalteparin, a low-molecular-weight heparin with a standard unfractionated heparin in patients with unstable angina pectoris. Materials and Methods: This was a 6-month, prospective, parallel, randomized and open-labeled study. Patients of angina pectoris were randomized to receive either unfractionated heparin or dalteparin for 5 days. They were followed for 21 days during three visits on 1 st, 5 th and 21 st days. A series of resting electrocardiogram were undertaken in all patients on each visit. Results: The frequency of the combined clinical outcome of death, myocardial infarction and recurrence of angina was similar during 21 days of follow-up with either dalteparin or intravenous unfractionated heparin. In patients who received dalteparin 2.43% patients developed minor bleeding in the form of epistaxis and 2.5% patients who received unfractionated heparin developed minor bleeding in the form of macroscopic hematuria. Conclusion: Dalteparin is as effective and safe as unfractionated heparin in the treatment of unstable angina. Dalteparin does not require routine laboratory monitoring as with unfractionated heparin.

Girish M.,Sdm Medical College And Hospital | Priyadarshini K.,Sdm Medical College And Hospital
International Journal of Pharma and Bio Sciences | Year: 2012

Objective: To investigate the effect of tinospora cordifolia (TC) on resutured incision and dead space wounds in albino rats. Materials and Methods: Resutured incision and dead space wounds were inflicted in albino rats under light ether anesthesia with aseptic precautions. Treatment group received tinospora cordifolia and control animals received vehicle orally for a period of 10 days. On the 11th day, after estimating breaking strength of resutured incision wounds, animals were sacrificed and granulation tissue removed from dead space wounds to estimate breaking strength, hydroxyproline content, quantification of granulation tissue and histopathological assessment in both control and treated groups. Results: TC significantly (P<0.05) promoted the healing process in both the wound models studied. Conclusion: TC promote wound healing, perioperative use of TC could promote the healing of surgical wounds.

Meravanige G.,Sdm Medical College And Hospital | Kamdod M.A.,Sdm Medical College And Hospital
International Journal of Pharma and Bio Sciences | Year: 2012

Objective: To investigate the effect of tinospora cordifolia (TC) on the healing of burn wounds in wistar rats and compare it with control and silver sulfadiazine treated groups. Materials and Methods: Partial thickness burn wounds were made on three groups of rats (n=6 in each group) at the nape of neck under ether anesthesia. The Burn wounds were treated topically with petroleum base, 1% silver sulfadiazine and 2% TC, respectively once daily till complete healing. The wound contraction rate and epithelialization time were observed. Data was analysed by one way ANOVA and Tukeys multiple post hoc procedures. Results: The mean epithelialization time was significantly (P<0.0004*) decreased in TC treated group compared to control and silver sulfadiazine groups. Percentage of wound contraction was significantly more on 4 th (P<0.0003*), 8th (P<0.0019*), 12th (P<0.0060*) and 16th day (P<0.0016*) in TC treated group in comparison to the control. Conclusion: Topical TC showed healing potential on burn wounds in wistar rats.

PubMed | Karnataka Institute of Medical science, SDM Medical College and Hospital and Sree Mookambika Institute of Medical science
Type: Journal Article | Journal: Journal of clinical and diagnostic research : JCDR | Year: 2014

Atrophic rhinitis (AR) is a chronic debilitating nasal mucosal disease predominantly prevalent in tropical countries. In the present case a 70-year-old female presented with a swelling in the right medial canthal area for six months and had features of Atrophic rhinitis with large septal perforation leading to saddle nose deformity. Computed tomography pictures were suggestive of ethmoidal mucocele and was later decompressed endoscopically. The sequelae and complications of AR like nasal septal perforation, saddle nose deformity, chronic rhinosinusitis (CRS), local and systemic spread of infection, atrophic pharyngitis, laryngitis, dacryocystitis and nasal myiasis have been reported in literature. To the best of our knowledge, this is the first reported case of AR presenting with ethmoidal mucocele. A case of AR with CRS is to be treated with caution as it can lead to complications as it is often neglected.

PubMed | SDM Medical College and Hospital
Type: Journal Article | Journal: Journal of clinical neonatology | Year: 2013

Congenital goiter presenting in the newborn period is very rare. We present a case of primary hypothyroidism presenting as congenital goiter in the newborn period with symptoms in the immediate postnatal life. Hormone replacement therapy was started leading to normal levels of free thyroxine and triiodothyronine. In face of maternal normal thyroid levels, dysharmonogenesis was considered to be the most probable cause of hypothyroidism.

PubMed | Karnataka Institute of Medical science and SDM Medical College and Hospital
Type: Journal Article | Journal: Journal of clinical and diagnostic research : JCDR | Year: 2014

Tornwaldts cyst is a benign cyst located in the upper posterior nasopharynx. It is a relatively rare lesion and most are small and asymptomatic whereas some cause nasal obstruction, postnasal drip, occipital headache or eustachian tube dysfunction. In our case a 28- year-old man presented with nasal obstruction since 10-years whose diagnostic nasal endoscopy showed a large well-encapsulated lesion arising from the posterior wall of the nasopharynx. A magnetic resonance imaging (MRI) was performed which was suggestive of a fluid filled cystic lesion. The patient underwent successful marsupialisation using endonasal endoscopic approach using rigid endoscopes and powered instrumentation. Histopathology of the aspirate revealed a respiratory lined epithelial cyst. Based on the clinical, radiological and histopathological findings a diagnosis of Tornwaldts cyst was made. We report this case to highlight the role of MRI in diagnosis and use of endoscopic assisted powered instrumentation for treatment of Tornwaldts cyst.

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