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Ujire, India

Sunil Kumar K.N.,Center for Research in Ayurveda and Allied science | Sangeetha B.,Center for Research in Ayurveda and Allied science | Rajalekshmi M.,Center for Research in Ayurveda and Allied science | Ravishankar B.,Center for Research in Ayurveda and Allied science | And 2 more authors.
Pharmacognosy Journal | Year: 2012

Introduction: Substitution of Cinnamomum tamala (tamalapatra) with similar looking leaves of other Cinnamomum species is frequent among the people who use this spice in their food. On account of characteristic flavor, leaves of Cinnamomum verum are in use as spice among the indigenous people living throughout Western Ghats. To differentiate and to establish the identity of any article of plant origin, a thorough chemical fingerprint profile is vital. This investigation is an attempt to fingerprint the chemical properties and composition of a Cinnamon derived leaf spice - C. verum. Methods: Leaves from plants of C. verum growing wildly in South Canara district were collected and subjected to physico-chemical, HPTLC and GC-MS analysis. Results: Physico-chemical standards, HPTLC fingerprint and essential oil composition of wild C. verum used as spice were derived. While physico-chemical constants will serve the purpose of standardisation, volatile oil composition will be a diagnostic test for the identification and differentiation of leaves of C. verum from C. tamala. Conclusion: Chemical fingerprint profile of C. verum has been established for the identification and differentiation of this species from tamalapatra. © 2012 Pharmacognosy Network Worldwide [Phcog.Net]. Source


Kumar K.N.S.,Center for Research in Ayurveda and Allied science | Sangeetha B.,Center for Research in Ayurveda and Allied science | Suchitra P.,Center for Research in Ayurveda and Allied science | Ravishankar B.,Center for Research in Ayurveda and Allied science | Yashovarma B.,SDM College Autonomous
Indian Journal of Natural Products and Resources | Year: 2016

Fruits of Balanites aegyptiaca (L.) Delile syn. B. roxburghii Planch (Family Balanitaceae) is considered as source of Ingudi of Ayurveda. It is a thorny tree with ovoid pulpy drupe type of fruit. In Ayurveda, Ingudi bark, leaf and fruits are said to be beneficial as blood purifier, diuretic, in leprosy, poisoning, ulcers, worm infestation, leucoderma, anorexia and constipation. Seed extract is hypotensive and the seed oil is used for burns and freckles. The unripe fruits are cathartic and the ripe ones are used in whooping cough and skin troubles. The fruits are also reported to possess antihperglycemic activity. In the present study, systematic pharmacognostical evaluation of ripe fruits has been carried out as per standard methodologies used for drug standardisation. Macroscopical, microscopical and physico-chemical features of the fruit have been documented. Preliminary phytochemical investigations indicated presence of carbohydrates, coumarins, triterpenoids and saponins. HPTLC fingerprint profile has been developed for methanol extract of pulp using diosgenin as standard. The result obtained from standardization of fruit established set diagnostic tests to authenticate genuine fruits. These parameters can be utilized for rapid identification of the drug as whole and as powder. © 2016, National Institute of Science Communication and Information Resources (NISCAIR). All rights reserved. Source


Sunil Kumar K.N.,Center for Research in Ayurveda and Allied science | Ravishankar B.,Center for Research in Ayurveda and Allied science | Yashovarma B.,SDM College Autonomous | Rajakrishnan R.,King Saud University | Thomas J.,King Saud University
Saudi Journal of Biological Sciences | Year: 2016

Helicanthes elastica (Desr.) Danser (Loranthaceae), commonly known as Indian mango mistletoe, is a parasitic shrub found widely growing on mango trees in southern India. Development of monographic quality standards is need of the hour for Pharmacopoeial/extra-Pharmacopoeial and folk medicinal plants. Systematic pharmacognostical evaluation of leaves of H. elastica has been carried out employing Pharmacopoeial procedures of testing herbal drugs. Macro-microscopic features of H. elastica leaf were recorded. Ethanolic extract was tested positive for alkaloids, steroids, carbohydrates, tannins, saponins and phenols. HPTLC fingerprint profile was developed for the identification of extracts using reference standard β-sitosterol glucoside. Results of the present investigation would serve as a source of pharmacognostical information and a document to control the quality of H. elastica (Desr.) Danser. © 2016 The Authors. Source


Sunil Kumar K.N.,Center for Research in Ayurveda and Allied science | Sangeetha B.,Center for Research in Ayurveda and Allied science | Rajalekshmi M.,Center for Research in Ayurveda and Allied science | Ravishankar B.,Center for Research in Ayurveda and Allied science | And 2 more authors.
Indian Journal of Natural Products and Resources | Year: 2013

Viscum orientale Willd. (Family-Viscaceae) is a large hemi-parasitic, much branched shrubs with opposite and oblanceolate leaves. Flowers are produced in dichasial cymose traid clusters developing into ovoid to sub-globose berry. The plant is claimed to have medicinal applications mainly in neuralgia, diabetes and in the treatment of itch. Systematic pharmacognostical evaluation of aerial parts of the plant has been carried out with focus on its macroscopy, microscopy, physicochemical and phytochemical characterization. Macroscopical and microscopical features of the mistletoe have been documented. Preliminary phytochemical investigations indicated presence of carbohydrate, flavonoid, steroids, triterpenoids and tannins. HPTLC fingerprint profile was developed for identification of the extract using reference standard. These parameters can be utilized for quick identification of the drug and are useful in establishing the identity of this mistletoe as whole or even in the form of powder. Source


Pushpendra P.,SDM College Autonomous | Sunil Kumar K.N.,Center for Research in Ayurveda and Allied science | Priyadarshini P.,SDM College Autonomous | Holla B.S.,SDM College Autonomous | And 2 more authors.
Journal of Traditional and Complementary Medicine | Year: 2016

In India, herbal medicines are mainly based on the Ayurvedic system. The main drawback of traditional medicines is a lack of standardized products. Standardization of any herbal formulation is essential in order to assess the quality, purity, safety, and efficacy of drugs based on the analysis of their active properties. Testing of Ayurvedic preparations using scientific methodologies will add to quality and authenticity of the product. This article reports standardization parameters for Hutabhuga¯di cu¯ra (HC) used traditionally in the treatment of Agnima¯ndya (digestive impairment), Pa¯ndu (anemia), Sopha (edema), and A¯rsa (piles). The formulation was prepared as per Ayurvedic Formulary of India, and it was standardized by organoleptic characterization, macro-microscopic evaluation, physicochemical testing, and thin-layer chromatography/high-performance thin-layer chromatography profiling employing a standard methodology. Results of the experiments conducted provided diagnostic characteristics to identify and standardize the formulation prepared using official ingredients of HC. Based on the data obtained, a monograph on quality standards for HC is proposed. The monograph based on the present investigation results would serve as a document to control the quality of HC. © 2014 Center for Food and Biomolecules, National Taiwan University. Source

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