Tainan, Taiwan
Tainan, Taiwan

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Patent
ScinoPharm Taiwan Ltd. | Date: 2016-08-24

The present invention provides novel crystalline forms of apremilast hemitoluene solvate, apremilast hydrate, and apremilast anhydrate and an amorphous form of apremilast, and processes for the preparation of these forms.


Patent
Scinopharm Taiwan Ltd. | Date: 2016-06-08

The present invention provides a process for the efficient preparation of enzalutamide.


Patent
Scinopharm Taiwan Ltd. | Date: 2013-03-27

A process for preparing a prostaglandin analogue comprising a step of converting a compound of formula (8): to the prostaglandin analogue, wherein R_(3 )represents hydrogen or a hydroxyl protecting group.


Patent
Scinopharm Taiwan LTD. | Date: 2013-07-25

The present invention provides novel processes for the preparation of Fondaparinux sodium by using the compound of formula ABC5 In some embodiments, the intermediates for the synthesis of Fondaparinux sodium, are also provided.


Patent
Scinopharm Taiwan LTD. | Date: 2013-07-25

The present invention provides improved processes of preparing Fondaparinux sodium comprising converting a compound of formula ABCDE4 to Fondaparinux sodium at a reaction pH of no more than about 9.0. In some embodiments, the intermediates for the synthesis of Fondaparinux sodium, are also provided.


Patent
ScinoPharm Taiwan LTD. | Date: 2014-06-26

The present invention provides intermediates for preparing abiraterone, and processes for preparing abiraterone and intermediates thereof. The intermediates include a compound of formula (IV): wherein R represents a hydroxy-protecting group.


Patent
Scinopharm Taiwan Ltd. | Date: 2015-10-28

Crystalline forms of pemetrexed diacid are provided (Forms 1 and 2) which are readily produced for either laboratory-scale or industrial scale. Processes for the preparation of Forms 1 and 2 are also provided.


This invention provides a novel method for the preparation of 2,3-disubstituted-4-oxy-cyclopentan-1-one compounds that are useful for the synthesis of prostaglandins and prostaglandin analogs of industrial relevance. The method comprises the metal-catalyzed asymmetric 1,4-conjugate addition of vinylboron compounds to 2-substituted-4-oxy-cyclopent-2-en-1-ones. This method relies on the use of less toxic, easily-handled reagents, and can be performed under milder conditions than offered by some conventional methods, affording 2,3-disubstituted-4-oxy-cyclopentan-1-one compounds enantio- and diastereoselectively, which are precursors to the said prostaglandin and prostaglandin analogs, in high yield.


Patent
ScinoPharm Taiwan Ltd. | Date: 2014-03-07

The present invention relates to a novel process of making ixabepilone, ixabepilone derivatives and analogues, and intermediates thereof.


Patent
ScinoPharm Taiwan Ltd. | Date: 2015-04-10

The present application discloses a stereoselective process for the preparation of -C-arylglucosides that does not require the use of conventional carbohydrate protecting groups.

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