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PubMed | Center for Community Medicine, Scientist and Laboratory Medicine
Type: Journal Article | Journal: Journal of clinical and diagnostic research : JCDR | Year: 2016

There is a balance between the oxidative and the anti-oxidative forces in human body. Some studies document decreased level of anti-oxidant in pre-eclampsia while other studies showed normal level of anti-oxidant in pre-eclampsia and the evidence is equivocal.The aim of the present study was to assess enzymatic anti-oxidant activities in pre-eclamptic women and compare it with normotensive pregnant women with period of gestation between 28 to 36 weeks.A community-based cross-sectional survey was conducted (from November 2012-December 2013) at the Ballabgarh Health and Demographic Surveillance System (HDSS) site which was managed by Centre for Community Medicine, All India Institute of Medical Sciences, New Delhi, India. All registered pregnant women with period of gestation between 28 weeks - 36 weeks were eligible for inclusion in the study. All eligible pregnant women were contacted through home visit. A total of 217 pregnant women were enrolled out of which 209 blood samples were collected from pregnant women. About three ml of blood from antecubital vein was drawn without use of tourniquet, under aseptic conditions. It was later analysed for the serum anti-oxidative measures {Malanoaldehyde, Vitamin C, Ferric Reducing Ability of Plasma (FRAP) levels}. Data were entered on Epi-Info version 3.5.4. Data management and analysis was carried out in Stata 11. The means were compared using t-test and p-value stated. Categorical data was analysed using chi-square test. Logistic regression was used and adjusted p-value was stated.A total of 217 pregnant women were eligible for the study and all were enrolled. Out of the 217 blood samples collected, eight samples accidently got destroyed. A total of 28 out of remaining 209 pregnant women (13.4%) had pre-eclampsia. Mean age (SD) was 22.4 (2.3) years, mean height (SD) was 156.6 (6.9) cm, mean weight (SD) was 65.1 (9.7) kg in pre-eclampsia group. In pre-eclampsia group mean serum levels of malanoaldehyde, vitamin C and FRAP was 4.2 (0.26) ng/dl, 0.83 (0.11) mg/dl, 678.0 (35.6) mol/L. It was 4.5 (0.09) ng/dl,0.88 (0.03) mg/dl, 599.3 (13.3) mol/L in normotensive pregnant women group respectively. The difference was statistically significant for FRAP levels only.Serum anti-oxidant levels are not raised among women with pre-eclampsia.


Prasad V.P.,Scientist | Simpson D.A.,Acting Keeper
Rheedea | Year: 2013

Different varieties of Pycreus flavidus (Retz.) T. Koyama reported from India were all found to be based on continuous variations of morphological characters. Hence all are treated here as P. flavidus.


PubMed | Technical Assistant., KEM Hospital, Scientist., Scientist and 6 more.
Type: Journal Article | Journal: The Journal of the Association of Physicians of India | Year: 2016

To identify the hematological manifestations and its association with serum ferritin levels in SLE patients from Western India.Ninety clinically diagnosed SLE patients fulfilling ACR criteria were included. Disease activity was assessed at the time of evaluation using Systemic Lupus Erythematosus Disease Activity Index (SLEDAI). Sera were tested for serum ferritin levels by ELISA (Calbiotech, USA). Autoantibodies such as ANA, anti-dsDNA by indirect immunofluorescence test (IFA- Bio-Rad, USA) and anti-cardiolipin antibodies (ACA) to IgG and IgM isotypes and Anti-2 GP antibodies to IgG and IgM isotypes were detected by ELISA using commercially available kits (Euroimmun, Lubeck, Germany).Out of 90 SLE patients studied, 41 patients (45.6%) showed hematological abnormalities, where anemia (82.9%), leucopenia (26.8%), autoimmune hemolytic anemia (AIHA) (14.6%) and idiopathic thrombocytopenic purpura (ITP) were noted in (34.1%) patients. MeanSD serum ferritin levels among SLE patients were 270.2266.0 ng/ml as compared to 29.015.8 ng/ml healthy normal controls (p<0.0001). A positive correlation between serum ferritin levels and SLEDAI scores (r= 0.2640, p=0.0124) and anti-dsDNA positivity was noted (r=0.32, p<0.0001). Serum ferritin levels were negatively correlated with hemoglobin levels (r=-0.5964, p=0.0001), WBC count (r=-0.1705, p=0.2316), platelet count ((r=-0.1701, P=0.2375), C3 levels (r=-0.4417, p=0.0034) and C4 levels (r=-0.0363, p=0.8215).Serum ferritin is an excellent marker of SLE which can be used for an evaluation of disease activity particularly in active stage of the disease mainly in patients having hematological and renal manifestations.


Tran N.,Scientist | Nguyen A.,Freelance Research Analyst and Translator | Wilson N.L.W.,Auburn University
Agribusiness | Year: 2014

Chloramphenicol is a broad-spectrum antibiotic that was historically used as a veterinary drug for farm animal disease treatment purposes and it is currently used in human treatment; however, this is a banned substance. This paper investigates the impact of advancing chloramphenicol analytical standards on crustacean imports in the EU15, Japan, and North America. The paper extends the work of Disdier and Marette (2010) by exploring the differential effect of standards on products. We use a Heckman sample selection specification to address zero trade at the product level. We show that submarkets function differently and respond differentially to the standard. Additionally, we show that the level of disaggregation matters in gravity modeling. © 2013 Wiley Periodicals, Inc.


Roy N.,Scientist | Choudhury R.N.P.,Institute of Physics, Bhubaneswar
Journal of Materials Science: Materials in Electronics | Year: 2016

As the variable dielectric constant, loss and some electric characteristics over the frequency and temperature band of operation make a material unsuitable for some devices, an attempt has been made through this work to obtain frequency–temperature independence of said parameters by suitable addition of metal oxide (MnO2) in lead-free ferroelectric (BaSr) TiO3 in the band of interest. The doping concentration of the oxide in Ba0.5Sr0.5TiO3 has been optimized for the purpose. The doping of manganese oxide reduces the loss by compensating the oxygen vacancies and the structural defects. With variable doping concentration of MnO2 dielectric loss is brought down to an acceptable limit (<10−3). Impedance and modulus spectroscopy of the prepared materials provide an insight into the electrical processes involved in it. The AC/DC conductivity analysis provides loss-conductivity spectrum for device utilization. © 2015, Springer Science+Business Media New York.


PubMed | Scientist and Acharya Nagarjuna University
Type: | Journal: International journal of biological macromolecules | Year: 2016

In this research, a serine protease was isolated and purified from Indian earthworm Pheretima posthumous by fractionation with ammonium sulfate followed by ion exchange and size exclusion chromatography. The molecular weight of purified protease was determined 29.5kDa by Maldi-TOF/MS. The enzyme exhibited a maximum proteolytic activity of 1.2U/ml with specific activity of 17.65U/mg at pH 8 and temperature 40C. 2D electrophoresis study illustrated purity of enzyme, purified as a single peptide and isoelectric point (pI) 4.5. The enzyme has shown tremendous stability and proteolytic activity in the wide range of pH range (4-12) and temperatures (20-60C). The kinetic constant Km and Vmax of purified protease were reported 0.09mg/ml and 23.25mg/ml/min. The enzyme also possesses excellent catalytic capacity with Kcat (341.9min


Gebrekidan B.,Mekelle University | Tegegne A.,Scientist | Regassa F.,Addis Ababa Institute of Technology
Animal Reproduction Science | Year: 2016

Retrospective studies were conducted in Kafta-Humera and Wukro areas of Tigray region of Ethiopia. A retrospective study was carried out on 12 herds consisting 2144 Begait cattle from pastoral and agro-pastoral areas to assess herd composition and calf-crop. To evaluate the reproductive performance, 210 cows were selected randomly from pastoral, agro-pastoral, confinement and crop-livestock production systems. All necessary data of reproductive parameters were collected through questionnaire surveys, group discussions and follow-up observations. SPSS software was applied to analyze the data. The result of the present study showed that the average calf-crop of 53% and 42.1% and annual calf mortality rate of 20.8% and 9.4%, were observed for pastoral and agro-pastoral production systems, respectively. The mean age at first service (AFS), age at first calving (AFC) and calving interval (CI) in months were 34.9, 43.9 and 12.9 in pastoral, 35.9, 45.0 and 14.0 in agro-pastoral, 34.4, 44.9 and 15.0 in confinement and 40.5, 49.5 and 19.6 in crop-livestock production systems, respectively. AFC and CI were significantly (P < 0.05) affected by site and production system. Significantly longer AFS, AFC and CI were noticed in crop-livestock system than in the other 3 production systems. However, CI was not affected by age and parity. © 2015 Elsevier B.V.


Sardar S.,Scientist | Babu K.A.,Scientist
Proceedings of the IEEE International Conference on VLSI Design | Year: 2014

Hardware implementation of a real-time, highly accurate face recognition system (FRS) is proposed in this correspondence. Face images are acquired from a CMOS sensor camera connected to Field Programmable Gate Array (FPGA)based reconfigurable hardware board using Cam Link interface. We used contrast limited adaptive histogram equalization (CLAHE) for image contrast enhancement, discrete wavelet transform (DWT) to remove variable illumination & select appropriate sub band and principal component analysis (PCA) with 35 principal components which is optimized for performance and speed. Finally, Restricted Coulomb Energy (RCE) based neural network (NN) classifier is used for face recognition. We have implemented the RCE based NN in FPGA and thus utilized the inherent parallelism effectively which is not possible with NN software implementation. The performance of our implementation is superior than face recognition software and hardware implementations, which are targeted to achieve higher recognition accuracy at faster rate using minimum computational resources. Our system recognizes a single image in real-time i.e. within 18 ms corresponding to 37 frames per second image capture. We have verified our proposed system with multiple standard face databases as well as using our own face data repository. © 2014 IEEE.


The relationship between both interstitial and blood glucose remains a debated topic, on which there is still no consensus. The experimental evidence suggests that blood and interstitial fluid glucose levels are correlated by a kinetic equilibrium, which as a consequence has a time and magnitude gradient in glucose concentration between blood and interstitium. Furthermore, this equilibrium can be perturbed by several physiological effects (such as foreign body response, wound-healing effect, etc.), with a consequent reduction of interstitial fluid glucose versus blood glucose correlation. In the present study, the impact of operating in the interstitium on continuous glucose monitoring systems (CGMs) will be discussed in depth, both for the application of CGMs in the management of diabetes and in other critical areas, such as tight glycaemic control in critically ill patients.


PubMed | Addis Ababa Institute of Technology, Scientist and Mekelle University
Type: | Journal: Animal reproduction science | Year: 2016

Retrospective studies were conducted in Kafta-Humera and Wukro areas of Tigray region of Ethiopia. A retrospective study was carried out on 12 herds consisting 2144 Begait cattle from pastoral and agro-pastoral areas to assess herd composition and calf-crop. To evaluate the reproductive performance, 210 cows were selected randomly from pastoral, agro-pastoral, confinement and crop-livestock production systems. All necessary data of reproductive parameters were collected through questionnaire surveys, group discussions and follow-up observations. SPSS software was applied to analyze the data. The result of the present study showed that the average calf-crop of 53% and 42.1% and annual calf mortality rate of 20.8% and 9.4%, were observed for pastoral and agro-pastoral production systems, respectively. The mean age at first service (AFS), age at first calving (AFC) and calving interval (CI) in months were 34.9, 43.9 and 12.9 in pastoral, 35.9, 45.0 and 14.0 in agro-pastoral, 34.4, 44.9 and 15.0 in confinement and 40.5, 49.5 and 19.6 in crop-livestock production systems, respectively. AFC and CI were significantly (P<0.05) affected by site and production system. Significantly longer AFS, AFC and CI were noticed in crop-livestock system than in the other 3 production systems. However, CI was not affected by age and parity.

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