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Kiselev O.I.,Scientific Research Institute of Influenza
Ukrain'skyi Biokhimichnyi Zhurnal | Year: 2013

The paper is devoted to studying the mechanisms of combined immunosuppression in pregnant women with influenza infection to develop arrangements for controlling these processes and for decreasing mortality from this infection. In this connection the author is dwelling on the following problems: -How are the fetus immune privilege and tolerance development provided? -What mechanisms do underlie the functional immunosuppresion under pregnancy? -Why are the infections especially dangerous for pregnant women? -Is there the code of the immune system control, and do viruses use this code? The paper deals with the problem of influence of endogenic viruses, which have penetrated the human genome more than 25 million years ago, on the great number of risks of development of various kinds of human pathologies: from infertility to pregnancy diseases; from development of malignant tumors to system pathology and autoimmune diseases. Source


Vasil'Eva A.S.,Saint Petersburg State University | Borisov E.N.,Saint Petersburg State University | Klotchenko S.A.,Scientific Research Institute of Influenza | Tver'Yanovich A.S.,Saint Petersburg State University | Tver'Yanovich Yu.S.,Saint Petersburg State University
Glass Physics and Chemistry | Year: 2014

Adhesion of protein materials with fluorescent stains to the film of Ga6Ge17S43 composition fabricated by the pulsed laser deposition was investigated. Resistance of the protein markers deposited onto the film to a washing in buffer isotonic solution was established. The obtained results provide the possibility to use these films for the development of protein biochips. © 2014 Pleiades Publishing, Ltd. Source


Buzitskaya Z.V.,Scientific Research Institute of Influenza | Sirotkin A.K.,Scientific Research Institute of Influenza | Gudkova T.M.,Scientific Research Institute of Influenza | Prochukhanova A.R.,Scientific Research Institute of Influenza | And 3 more authors.
Molecular Biology | Year: 2012

In the surveillance of the incidence of rubella in the northwestern region of Russia, an analysis was conducted of swabs from the noses and pharynxes of 37 patients with rubella treated in Solovev District Military Clinical Hospital No. 442. To isolate the virus, the RK-13 cell line was used, in total 22 strains were allocated. The strains of the Rubella virus isolated in St. Petersburg during the 2007 outbreak belong to the 1E genotype. In the culture of RK-13 cells, changes of cellular morphogenesis and the formation of replicative complexes, as well as the shells of virions of rubella viruses, were detected. © 2012 Pleiades Publishing, Ltd. Source

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