SCHWIND eye Technology solutions

Kleinostheim, Germany

SCHWIND eye Technology solutions

Kleinostheim, Germany
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Hammer A.,University of Geneva | Richoz O.,University of Geneva | Mosquera S.A.,SCHWIND eye Technology solutions | Tabibian D.,University of Geneva | And 3 more authors.
Investigative Ophthalmology and Visual Science | Year: 2014

Purpose. New corneal cross-linking (CXL) devices are capable of using higher UV-A light irradiances than used in original CXL protocols. The Bunsen-Roscoe law states that a photochemical reaction should stay constant if the delivered total energy is kept constant; however, little clinical data are available to support this hypothesis. Methods. We investigated the biomechanical properties of four groups (n = 50 each) of porcine corneas. Three groups were exposed to riboflavin 0.1 % and UV-A irradiation of equal total energy (3 mW/cm2 for 30 minutes, 9 mW/cm2 for 10 minutes, and 18 mW/cm2 for 5 minutes). Controls were exposed to riboflavin 0.1% without irradiation. Young's modulus of 5-mm wide corneal strips was used as an indicator of corneal stiffness. Results. We observed a decreased stiffening effect with increasing UV-A intensity. Young's modulus at 10% strain showed significant differences between 3 mW/cm2 and 9 mW/cm2 (P = 0.002), 3 mW/cm2 and 18 mW/cm2 (P = 0.0002), 3 mW/cm2 and the control group (P < 0.0001), and 9 mW/cm2 and the control group (P = 0.015). There was no difference between 18 mW/cm2 and the control group (P = 0.064) and between 9 mW/cm2 and 18 mW/cm2 (P = 0.503). Conclusions. The biomechanical effect of CXL decreased significantly when using high irradiance/short irradiation time settings. Intrastromal oxygen diffusion capacity and increased oxygen consumption associated with higher irradiances may be a limiting factor leading to reduced treatment efficiency. Our results regarding the efficiency of high-irradiance collagen cross-linking (CXL) raise concerns about the clinical efficiency of the new high-irradiance CXL devices already used in clinical practice without proper validation. © 2014 The Association for Research in Vision and Ophthalmology, Inc.


Shraiki M.,FH Darmstadt | Arba-Mosquera S.,SCHWIND eye Technology solutions | Arba-Mosquera S.,University of Valladolid
Investigative Ophthalmology and Visual Science | Year: 2011

Purpose. To evaluate ablation algorithms and temperature changes in laser refractive surgery. Methods. The model (virtual laser system [VLS]) simulates different physical effects of an entire surgical process, simulating the shot-by-shot ablation process based on a modeled beam profile. The model is comprehensive and directly considers applied correction; corneal geometry, including astigmatism; laser beam characteristics; and ablative spot properties. Results. Pulse lists collected from actual treatments were used to simulate the temperature increase during the ablation process. Ablation efficiency reduction in the periphery resulted in a lower peripheral temperature increase. Steep corneas had lesser temperature increases than flat ones. The maximum rise in temperature depends on the spatial density of the ablation pulses. For the same number of ablative pulses, myopic corrections showed the highest temperature increase, followed by myopic astigmatism, mixed astigmatism, phototherapeutic keratectomy (PTK), hyperopic astigmatism, and hyperopic treatments. Conclusions. The proposed model can be used, at relatively low cost, for calibration, verification, and validation of the laser systems used for ablation processes and would directly improve the quality of the results. © 2011 The Association for Research in Vision and Ophthalmology, Inc.


De Ortueta D.,Aurelios Augenzentrum Recklinghausen | Magnago T.,SCHWIND Eye Technology solutions | Triefenbach N.,SCHWIND Eye Technology solutions | Arba Mosquera S.,SCHWIND Eye Technology solutions | And 2 more authors.
Journal of Refractive Surgery | Year: 2012

PURPOSE: To evaluate the thermal load of ablation in high-speed laser corneal refractive surgery with the AMARIS excimer laser (SCHWIND eye-tech-solutions). METHODS: Thermal load from refractive corrections on human corneas using a 500-Hz laser system with a fluence of 500 mJ/cm 2 and aspheric ablation profiles was recorded with an infrared thermography camera. Each single in vivo measurement was analyzed and temperature values were evaluated. RESULTS: Overall, the maximum temperature change of the ocular surface induced by the refractive ablations was ≤4° C. The increase in the peak temperature of the ocular surface never exceeded 35° C in any case. This low thermal load was independent of the amount of correction the eye achieved. CONCLUSIONS: The thermal load of the ablation in highspeed laser corneal refractive surgery was minimized using a computer algorithm to control the peak temperature to avoid corneal collagen denaturation with minimal compromise on treatment duration. Copyright © SLACK Incorporated.


Luger M.H.A.,VisionClinics | Ewering T.,Schwind Eye Technology solutions | Arba-Mosquera S.,Schwind Eye Technology solutions
Journal of Cataract and Refractive Surgery | Year: 2012

Purpose: To compare the postoperative efficacy, safety, and higher-order-aberrations (HOAs) between transepithelial photorefractive keratectomy (PRK) and alcohol-assisted PRK in contralateral eyes. Setting: Private clinic, Utrecht, The Netherlands. Design: Comparative case series. Methods: Consecutive patients were randomized to have transepithelial PRK in 1 eye and alcohol-assisted PRK in the contralateral eye. In both eyes, aspheric treatments were planned with Custom Ablation Manager software and ablations performed with the Schwind Amaris system. Clinical outcomes were predictability, refraction, visual acuity, wavefront aberrations, and contrast and glare sensitivity. Paired t tests were applied for statistics. Results: The study evaluated 66 eyes (33 patients). All patients completed the 1-year follow-up. At 1-year, 97% of eyes in both groups achieved an uncorrected distance visual acuity (UDVA) of 0.1 logMAR or better. No eye lost 2 or more lines of corrected distance visual acuity (CDVA); 97% of transepithelial PRK eyes and 91% of alcohol-assisted PRK eyes were within ±0.50 diopter (D) of the targeted refraction. The postoperative mean spherical equivalent was +0.07 D ± 0.23 (SD) and +0.01 ± 0.27 D, respectively. Conclusions: The CDVA, UDVA, and safety outcomes between transepithelial PRK and alcohol-assisted PRK were comparable. Profiles for both techniques applied to regular corneas preserved the eye's natural HOAs. Transepithelial PRK is faster to perform and it is an all-laser procedure, which might be less stressful for the patient. Financial Disclosure: Mr. Ewering and Mr. Arba-Mosquera are employees of Schwind eye-tech-solutions. Dr. Luger has no financial or proprietary interest in any material or method mentioned. © 2012 ASCRS and ESCRS.


Luger M.H.A.,VisionClinics | Ewering T.,Schwind Eye Technology Solutions | Arba-Mosquera S.,Schwind Eye Technology Solutions
Cornea | Year: 2013

Purpose: To analyze simultaneous vision (distance and near) 1-year after biaspheric multifocal central presbyLASIK treatments for hyperopia and myopia with or without astigmatism. Methods: Patients were treated to correct distance ametropias and alleviating presbyopic symptoms simultaneously. All patients have been treated in Presby aberration-free mode using FemtoLASIK for Sphere from-7.00 to +3.25 diopters (D), astigmatism up to 3.00 D, and addition up to +2.75 D. No eye had previous corneal refractive surgery. Preoperative corneal curvature ranged between 40 and 48 D, with pachymetry thicker than 500 μm. Preoperative corrected distance visual acuity was 0.1 logarithm of the minimum angle of resolution (logMAR) or better, with near vision of 0.2 logRAD or better with addition up to +2.50 D. Results: Sixty-six eyes treated bilaterally using PresbyMAX software were reviewed. For 31 patients (94%), 1-year follow-up was completed. At 1 year, 70% of patients achieved uncorrected distance visual acuity 0.1 logMAR or better, 84% patients obtained uncorrected near visual acuity 0.1 logRAD or better, and 83% of eyes were within 0.75 D of defocus. Postoperative mean spherical equivalent refraction was-0.47 ± 0.44 D. Stability was achieved from the 6-week follow-up. Eighty-five percent of patients achieved simultaneously uncorrected distance visual acuity 0.2 logMAR or better and uncorrected near visual acuity 0.2 logRAD or better. Conclusion: Patient selection and expectation management is essential to achieve patient satisfaction. Even though optically the results are predictable and good, some patients find it difficult to adapt to the compromise and others are dissatisfied by the minor loss of distance visual acuity. Certain individuals are best suited for PresbyMAX. A test with multifocal contact lenses or trial frames that creates slightly defocused images can be used to simulate postoperative visual impressions and verify patient acceptance. © 2013 Lippincott Williams & Wilkins.


Luger M.H.A.,VisionClinics | Ewering T.,SCHWIND Eye Technology solutions | Arba-Mosquera S.,SCHWIND Eye Technology solutions
Journal of Refractive Surgery | Year: 2014

PURPOSE: To analyze distance and near vision after a nonwavefront-guided Presby reversal treatment targeting a monofocal cornea in a patient intolerant to multifocality in the dominant eye. METHODS: Case report. RESULTS: An originally myopic patient treated for correcting distance ametropia and simultaneously alleviating presbyopic symptoms resulted in intolerance to the induced multifocality. Twenty-one months after the bi-aspheric multifocal treatment, the patient was treated with PresbyMAX reversal (SCHWIND eye-tech-solutions, Kleinostheim, Germany) to remove the previously induced multifocality. Original corrected distance visual acuity (CDVA) was -0.1 logMAR (20/16 Snellen) with +0.8 logMAR (J12) uncorrected near visual acuity (UNVA) and changed to CDVA +0.1 logMAR (20/25 Snellen) with +0.2 logMAR (J4) UNVA before the Presby reversal procedure (all monocularly). Three months after the reversal treatment, uncorrected distance visual acuity and CDVA were both -0.1 logMAR (20/16 Snellen), and the patient was emmetropic and had no further visual complaint for distance, but at the cost of losing the UNVA. CONCLUSIONS: Nonwavefront-guided Presby reversal treatments targeting a monofocal cornea after bi-aspheric ablation profile were successful. Copyright © SLACK Incorporated.


Baudu P.,Clinique Avicenne | Penin F.,Schwind France Eye Technology Solutions | Arba Mosquera S.,Schwind Eye Technology Solutions
American Journal of Ophthalmology | Year: 2013

Purpose: To analyze the uncorrected binocular performance after biaspheric multifocal central presbyopic laser in situ keratomileusis treatments. Design: Retrospective, interventional case series. Methods: setting. Private clinical practice. patient or study population. Three hundred fifty-eight presbyopic patients (43% males, 82 myopic), bilaterally treated, suitable for laser in situ keratomileusis, with monocular corrected distance visual acuity of 20/32 or better. intervention or observation procedure(s). PresbyMAX (Schwind Eye-Tech-Solutions GmbH and Co) biaspheric multifocal ablation. main outcome measures. Binocular uncorrected distance visual acuity (UDVA) and near visual acuity (UNVA) after surgery and their changes compared with corrected distance visual acuity and corrected near visual acuity before surgery. Results: At 6 months, 76% of patients achieved a UDVA of 0.1 logarithm of the minimal angle of resolution (logMAR; Snellen equivalent, 20/25) or better, 91% of patients obtained a UNVA of 0.1 logarithmic of the reading acuity determination (logRAD) (p3) or better, and 99% of patients were within 1 diopter of defocus. Postoperative mean spherical equivalent was -0.17 ± 0.34 diopter. Ninety-six percent of patients achieved a UDVA of 0.2 logMAR (Snellen equivalent, 20/32) or better and a UNVA of 0.2 logRAD (p4) or better. Mean binocular corrected distance visual acuity degraded from 0.00 ± 0.01 logMAR (Snellen equivalent, 20/20) to a UDVA of 0.09 ± 0.07 logMAR (Snellen equivalent, 20/25). Mean binocular corrected near visual acuity degraded from 0.02 ± 0.01 logRAD (p2) to a UNVA of 0.07 ± 0.07 logRAD (p2). Conclusions: Although optically the results are predictable, approximately 17% of the patients did not obtain objectively successful outcomes. In presbyopic patients without symptomatic cataracts, but with refractive errors, the PresbyMAX will decrease the presbyopic symptoms and correct far distance refraction in the same treatment, offering spectacle-free vision in daily life in most of the patients. Further investigation is necessary to evaluate the overall benefit of this procedure. © 2013 BY ELSEVIER INC. ALL RIGHTS RESERVED.


Arba-Mosquera S.,SCHWIND eye Technology solutions | Verma S.,SCHWIND eye Technology solutions
Biomedical Optics Express | Year: 2013

We suggest a general method to determine the optimum laser parameters for maximizing the ablation efficiency for different materials (in particular human cornea) at different incidence angles. The model is comprehensive and incorporates laser beam characteristics and ablative spot properties. The model further provides a method to convert energy fluctuations during ablation to equivalent ablation deviations in the cornea. The proposed model can be used for calibration, verification and validation purposes of laser systems used for ablation processes at relatively low cost and would directly improve the quality of results. © 2013 Optical Society of America.


Mosquera S.A.,SCHWIND Eye Technology Solutions | Verma S.,SCHWIND Eye Technology Solutions
Journal of Biomedical Optics | Year: 2015

The objective is to characterize the impact of different ablation parameters on the thermal load during corneal refractive surgery by means of excimer laser ablation on porcine eyes. One hundred eleven ablations were performed in 105 porcine eyes. Each ablation was recorded using infrared thermography and analyzed mainly based on the two tested local frequencies (40 Hz, clinical local frequency; 1000 Hz, no local frequency). The change in peak corneal temperature was analyzed with respect to varying ablation parameters [local frequency, system repetition rate, pulse energy, optical zone (OZ) size, and refractive correction]. Transepithelial ablations were also compared to intrastromal ablations. The average of the baseline temperature across all eyes was 20.5°C±1.1 (17.7°C to 22.2°C). Average of the change in peak corneal temperature for all clinical local frequency ablations was 5.8°C±0.8 (p=3.3E-53 to baseline), whereas the average was 9.0°C±1.5 for all no local frequency ablations (p=1.8E-35 to baseline, 1.6E-16 to clinical local frequency ablations). A logarithmic relationship was observed between the changes in peak corneal temperature with increasing local frequency. For clinical local frequency, change in peak corneal temperature was comparatively flat (r2=0.68 with a range of 1.5°C) with increasing system repetition rate and increased linearly with increasing OZ size (r2=0.95 with a range of 2.4°C). Local frequency controls help maintain safe corneal temperature increase during excimer laser ablations. Transepithelial ablations induce higher thermal load compared to intrastromal ablations, indicating a need for stronger thermal controls in transepithelial refractive procedures. © The Authors. Published by SPIE under a Creative Commons Attribution 3.0 Unported License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its.


Arba-Mosquera S.,University of Valladolid | Triefenbach N.,SCHWIND Eye Technology Solutions
Journal of Modern Optics | Year: 2012

The relative ablation efficiency at different materials (in particular human cornea and poly(methyl methacrylate) (PMMA)) was analysed. A comprehensive model, which directly considers applied correction, including astigmatism, as well as laser beam characteristics and ablative spot properties has been developed. The model further provides a method to convert the deviations in achieved ablation observed in PMMA to equivalent deviations in the cornea. Radiant exposures from about 90mJ/cm 2 to about 500mJ/cm 2 correspond to cornea-to-PMMA ablation ratios of about 9 and about 1.7, respectively (about 7 and 1.3 optically). Super-Gaussian order from simple Gaussian profile to flat-top profile, and for a radiant exposure of 250mJ/cm 2, correspond to cornea-to-PMMA ratios of about 2.3 and about 1.6, respectively (about 1.7 and about 1.2 optically). For a Gaussian beam of 160mJ/cm 2 radiant exposure, a severe overcorrection of +50% in PMMA corresponds only to an overcorrection of +29% on corneal tissue, whereas a moderate overcorrection of +20% in PMMA corresponds to an overcorrection of +12% on corneal tissue. For a severe undercorrection of 50% ablation observed in PMMA, the range for radiant exposures from about 90mJ/cm 2 to about 500mJ/cm 2 correspond to corneal undercorrections of about 14% to about 40%, respectively. The proposed model can be used for calibration, ablation pattern test and development, verification and validation purposes of laser systems used for ablation processes at relatively low cost and would directly improve the quality of results. © 2012 Copyright Taylor and Francis Group, LLC.

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