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Murthykumar K.,Saveetha Dental College and Hospitals
Journal of Pharmaceutical Sciences and Research | Year: 2013

Dental caries is a infectious microbiologic disease of the tooth that results in localized dissolution and destruction of calcified tissues. Its seen in all age groups, few preventive agents have been evaluated to prevent the caries. Xylitol, a polysugar, obtained from birch tree has been shown to reduce dental caries when mixed with food, chewing gums and milk. Dental caries are prevalent in acidic pH where Streptoccocus mutans (MS) ferment and does resulting in demineralization of tooth this acidic pH is created by consumption of carbohydrate foods which results in decreased salivary secretion which in turn result demineralization of tooth, where as Streptococcus mutans cannot ferment xylitol thus it reduces MS by altering their metabolic pathway and enhance remineralization and helps arrest dentinal caries. Reduction in caries rate are greater, when xylitol is used as the sugar substitutes. This review discuss the taste acceptability of xylitol in milk as a step towards measuring the effectiveness for the reduction of dental caries.

Kumar M.D.,Saveetha Dental College and Hospitals
Research Journal of Pharmacy and Technology | Year: 2016

Aim: To determine the anatomical measurement of presence, horizontal distance and vertical distance of submandibular fossa. The submandibular fossa is a fossa in the mandible for the submandibular gland. It is a shallow depression on either side on the inner surface of the body of the mandible, inferior to the mylohyoid line, lodging the submandibular gland. Using the dried mandibles, the horizontal distance from the position of the mental foramen as well as the vertical distance between the inferior border of the mandible and the mylohyoid line were measured at definite points.There were no significant statistical difference in genders, sides, and tooth loss.The main aim of this study is that the horizontal and the vertical distances of the submandibular fossa are determined for the purpose of placing the dental implants such as endosseousimplants. © RJPT All right reserved.

Monalisa R.,Saveetha Dental College and Hospitals
Research Journal of Pharmacy and Technology | Year: 2016

Aim: The aim of the article is to do a literature review on the role of leptin in obesity. Objective: This review article deals with the role of leptin in obesity. Leptin is a hormone made by fat cells which regulates the amount of fat stored in the body. Background: Leptin is a 16- kilodalton adipocyte-derived hormone that circulates in the serum in the free and bound form. Serum levels of leptin reflect the amount of energy stored in adipose tissue. Short-term energy imbalance as well as serum levels of several cytokines and hormones influence circulating leptin levels. Leptin acts by binding to specific receptors in the hypothalamus to alter the expression of several neuropeptides that regulate neuroendocrine function and energy intake and expenditure. Thus, leptin plays an important role in the pathogenesis of obesity and eating disorders and is thought to mediate the neuroendocrine response to food deprivation. Reason: The reason of the review is to highlight the role of leptin in obesity. © RJPT All right reserved.

Noor S.S.S.E.,Saveetha Dental College and Hospitals
Research Journal of Pharmacy and Technology | Year: 2016

Aim: To make a review on tobacco associated malignant and non malignant lesions of the oral cavity. Objective: To have a better knowledge on the tobacco associated lesions of oral cavity. Back ground: The excessive use of tobacco products has been associated with various lesions in the oral cavity. Tobacco associated lesions include tooth stains, abrasions, smokers melanosis, acute necrotizing, ulcerative gingivitis and other periodontical conditions, burns, and keratotic patches, black hairy tongue, nicotinic stomatitis, palatal erosions, leukoplakia, epithelial dysplasia and squamous cell carcinoma. A routine intraoral examination by a dental health professional can reveal most of these lesions at an early stage, and early intervention may prevent serious sequelae. Here we describe malignant and non malignant lesions associated with tobacco use, basic biopsy principles for such lesions and intervention stratagies that dental professionals may use to reduce the chances of their patients developing precancerous lesions. The significance and treatment of non malignant and malignant lesions are described here. Reason:As oral lesions are very much common in population I was interested to know about the lesions associated due to conception of tobacco. © RJPT All right reserved.

Vane S.C.S.,Saveetha Dental College and Hospitals
Research Journal of Pharmacy and Technology | Year: 2016

Aim: To do a literature review on complications, management and use of oral hygiene techniques for people who wear oral and peri oral piercings. Objective: This article tries to decode the various complications of the oral cavity associated with piercing and methods to avoid potential after effects such as their post- management and oral hygiene techniques. Background: Piercing of the oral cavity is a popular form of expression of one’s self, especially in the Western world, which has several associated complications. Oral piercing of tongue, cheek, uvula and frenum are common between young adults. Tongue piercings are the most common. The first effect of piercing would be swelling of that region. To avoid embedding of the jewellery into mucosa, they are initially large and then the size subsequently shortened to avoid accidental biting and causing trauma to teeth. The side effects include swelling, pain, fractured teeth, infection, hyper salivation, gingival trauma and difficulty in mastication. The article will include various precautionary methods to avoid the after effects and their management such as diet recommendations. Reason For Research: To understand the complications of this popular body art. © RJPT All right reserved.

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