Savannah State University is a four-year, state-supported, historically black university located in Savannah, Georgia. Savannah State is the oldest public historically black university in Georgia. Savannah State University's mission statement is "to graduate students who are prepared to perform at higher levels of economic productivity, social responsibility, and excellence in their chosen career fields of endeavor in a changing global community.". The University is a member-school of Thurgood Marshall College Fund.Savannah State operates three colleges and the Office of Graduate Studies and Sponsored Research . It also participates in research centers and programs . Wikipedia.
Savannah State University | Date: 2016-11-29
Benzofuran compound, composition thereof, kit thereof, and/or method thereof. A benzofuran-2-carboxamide moiety may be N-arylated and/or N-alkylated, and the resulting benzofuran compound may be a sigma receptor ligand that binds to, e.g., a 1 receptor and/or a 2 receptor with relatively high affinity and/or selectivity. For example, the benzofuran compound may be 5,6-dimethoxy-3-methyl-N-phenyl-N-(3-(piperidin-1-yl)propyl)benzofuran-2-carboxamide, 3-methyl-N-phenyl-N-(3-(piperidin-1-yl)propyl)benzofuran-2-carboxamide, or 6-methoxy-3-methyl-N-phenyl-N-(3-(piperidin-1-yl) propyl)benzofuran-2-carboxamide. The composition may include the benzofuran compound and a pharmaceutically acceptable carrier.
Tang S.,Tianjin University of Technology |
Baker G.A.,University of Missouri |
Zhao H.,Savannah State University
Chemical Society Reviews | Year: 2012
In recent years, the designer nature of ionic liquids (ILs) has driven their exploration and exploitation in countless fields among the physical and chemical sciences. A fair measure of the tremendous attention placed on these fluids has been attributed to their inherent designer nature. And yet, there are relatively few examples of reviews that emphasize this vital aspect in an exhaustive or meaningful way. In this critical review, we systematically survey the physicochemical properties of the collective library of ether- and alcohol-functionalized ILs, highlighting the impact of ionic structure on features such as viscosity, phase behavior/transitions, density, thermostability, electrochemical properties, and polarity (e.g. hydrophilicity, hydrogen bonding capability). In the latter portions of this review, we emphasize the attractive applications of these functionalized ILs across a range of disciplines, including their use as electrolytes or functional fluids for electrochemistry, extractions, biphasic systems, gas separations, carbon capture, carbohydrate dissolution (particularly, the (ligno)celluloses), polymer chemistry, antimicrobial and antielectrostatic agents, organic synthesis, biomolecular stabilization and activation, and nanoscience. Finally, this review discusses anion-functionalized ILs, including sulfur- and oxygen-functionalized analogs, as well as choline-based deep eutectic solvents (DESs), an emerging class of fluids which can be sensibly categorized as semi-molecular cousins to the IL. Finally, the toxicity and biodegradability of ether- and alcohol-functionalized ILs are discussed and cautiously evaluated in light of recent reports. By carefully summarizing literature examples on the properties and applications of oxy-functional designer ILs up till now, it is our intent that this review offers a barometer for gauging future advances in the field as well as a trigger to spur further contemplation of these seemingly inexhaustible and - relative to their potential - virtually untouched fluids. It is abundantly clear that these remarkable fluidic materials are here to stay, just as certain design rules are slowly beginning to emerge. However, in fairness, serendipity also still plays an undeniable role, highlighting the need for both expanded in silico studies and a beacon to attract bright, young researchers to the field (406 references). © 2012 The Royal Society of Chemistry.
Wagle D.V.,University of Missouri |
Zhao H.,Savannah State University |
Baker G.A.,University of Missouri
Accounts of Chemical Research | Year: 2014
ConspectusDeep eutectic solvents (DESs) represent an alternative class of ionic fluids closely resembling room-temperature ionic liquids (RTILs), although, strictly speaking, they are distinguished by the fact that they also contain an organic molecular component (typically, a hydrogen bond donor like a urea, amide, acid, or polyol), frequently as the predominant constituent. Practically speaking, DESs are attractive alternatives to RTILs, sharing most of their remarkable qualities (e.g., tolerance to humidity, negligible vapor pressure, thermostability, wide electrochemical potential windows, tunability) while overcoming several limitations associated with their RTIL cousins. Particularly, DESs are typically, less expensive, more synthetically accessible (typically, from bulk commodity chemicals using solvent/waste-free processes), nontoxic, and biodegradable.In this Account, we provide an overview of DESs as designer solvents to create well-defined nanomaterials including shape-controlled nanoparticles, electrodeposited films, metal-organic frameworks, colloidal assemblies, hierarchically porous carbons, and DNA/RNA architectures. These breakthroughs illustrate how DESs can fulfill multiple roles in directing chemistry at the nanoscale: acting as supramolecular template, metal/carbon source, sacrificial agent (e.g., ammonia release from urea), and/or redox agent, all in the absence of formal stabilizing ligand (here, solvent and stabilizer are one and the same).The ability to tailor the physicochemical properties of DESs is central to controlling their interfacial behavior. The preorganized "supramolecular" nature of DESs provides a soft template to guide the formation of bimodal porous carbon networks or the evolution of electrodeposits. A number of essential parameters (viscosity, polarity, surface tension, hydrogen bonding), plus coordination with solutes/surfaces, all play significant roles in modulating species reactivity and mass transport properties governing the genesis of nanostructure. Furthermore, DES components may modulate nucleation and growth mechanisms by charge neutralization, modification of reduction potentials (or chemical activities), and passivation of particular crystal faces, dictating growth along preferred crystallographic directions. Broad operational windows for electrochemical reactions coupled with their inherent ionic nature facilitate the electrodeposition of alloys and semiconductors inaccessible to classical means and the use of cosolvents or applied potential control provide under-explored strategies for mediating interfacial interactions leading to control over film characteristics.The biocompatibility of DESs suggests intriguing potential for the construction of biomolecular architectures in these novel media. It has been demonstrated that nucleic acid structures can be manipulated in the ionic, crowded, dehydrating (low water activity) DES environment-including the adoption of duplex helical structures divergent from the canonical B form and parallel G-quadruplex DNA persisting near waters boiling point-challenging the misconception that water is a necessity for maintenance of nucleic acid structure/functionality and suggesting an enticing trajectory toward DNA/RNA-based nanocatalysis within a strictly anhydrous medium.DESs offer tremendous opportunities and open intriguing perspectives for generating sophisticated nanostructures within an anhydrous or low-water medium. We conclude this Account by offering our thoughts on the evolution of the field, pointing to areas of clear and compelling utility which will surely see fruition in the coming years. Finally, we highlight a few hurdles (e.g., need for a universal nomenclature, absence of water-immiscible, oriented-phase, and low-viscosity DESs) which, once navigated, will hasten progress in this area. © 2014 American Chemical Society.
Zhao H.,Savannah State University
Journal of Chemical Technology and Biotechnology | Year: 2010
Ionic liquids (ILs) have evolved as a new type of non-aqueous solvents for biocatalysis, mainly due to their unique and tunable physical properties.Anumber of recent review papers have described a variety of enzymatic reactions conducted in IL solutions; on the other hand, it is important to systematically analyze methods that have been developed for stabilizing and activating enzymes in ILs. This review discusses the biocatalysis in ILs from twounique aspects (1) factors that impact the enzyme's activity and stability, (2)methods that have been adopted or developed to activate and/or stabilize enzymes in ionic media. Factors that may influence the catalytic performance of enzymes include IL polarity, hydrogen-bond basicity/anion nucleophilicity, IL network, ion kosmotropicity, viscosity, hydrophobicity, the enzyme dissolution, and surfactant effect. To improve the enzyme's activity and stability in ILs, major methods being explored include the enzyme immobilization (on solid support, sol-gel, or CLEA), physical or covalent attachment to PEG, rinsing with n-propanolmethods (PREP and EPRP), water-in-ILmicroemulsions, IL coating, and the design of enzyme-compatible ionic solvents. It is exciting to notice that new ILs are being synthesized to be more compatible with enzymes. To utilize the full potential of ILs, it is necessary to further improve these methods for better enzyme compatibility. This is what has been accomplished in the field of biocatalysis in conventional organic solvents. © 2010 Society of Chemical Industry.
Agency: NSF | Branch: Standard Grant | Program: | Phase: HIST BLACK COLLEGES AND UNIV | Award Amount: 282.11K | Year: 2016
The Historically Black Colleges and Universities-Undergraduate Program (HBCU-UP) Research Initiation Awards (RIAs) provide support to STEM junior faculty at HBCUs who are starting to build a research program, as well as for mid-career faculty who may have returned to the faculty ranks after holding an administrative post or who need to redirect and rebuild a research program. Faculty members may pursue research at their home institution, at an NSF-funded Center, at a research intensive institution or at a national laboratory. The RIA projects are expected to help further the faculty members research capability and effectiveness, to improve research and teaching at his or her home institution, and to involve undergraduate students in research experiences. With support from the National Science Foundation, Savannah State University (SSU) will conduct research aimed at understanding the influence of physical dynamics on the mesopelagic community structure and its role in top predator ecology. This project will be used to enhance teaching and learning at SSU and thus, is geared for increasing marketable quantitative skills in undergraduate education and for preparing our diverse undergraduates for graduate school or the job market. The research and educational efforts will contribute to the mission of SSUs College of Sciences and Technology (COST) to delivering high quality education, scholarship, and research in STEM by expanding its existing research capacity. In addition, by providing the opportunities for undergraduates to participate in cutting-edge oceanographic research and gain mentorship in advanced oceanographic data methods, this project addresses the need to equip a diverse student population for the next generation of geosciences, particularly with the research and quantitative skills that will be in greatest demand in the coming years/decades.
The goal of the proposed study is to understand the relationships among the oceanography of the mesopelagic community and marine mammal top predators. The specific aims of this project are to: 1) describe the temporal variability of the physical oceanography of the region; 2) describe the temporal variability in the mesopelagic community; and 3) determine temporal linkages among the physical oceanographic setting, mesopelagic prey field, and vocalizing deep-diving marine mammals. This project will result in the application of sensors in a novel way, providing an example of the application and design of multi-sensor mooring package specifically targeted for the measurements of complex ecosystem interactions ranging from the physical habitat and the mesopelagic prey community all the way to apex predators. The findings from this study will provide a great step towards improving the study of marine top predators and their prey, whose focus is shifting from distribution and abundance to ecosystem interactions. This project will be conducted in collaboration with Duke University.
Savannah State University | Date: 2016-03-09
An apparatus may include a separator and/or a discharger. A separator may include a separator channel, an influent portion configured to allow the passage of a first fluid into a separator channel, an effluent portion disposed above an influent portion and/or a fluid-lift portion between an influent portion and an effluent portion. A discharger may be disposed below a fluid-lift portion and/or may include a portion external to a separator channel, which may include a downward angle relative to an effluent portion and/or may be configured to minimize the passage of a second fluid into a discharger as the second fluid buoyantly travels in a separator channel from an influent portion to an effluent portion. A second fluid may have a density that is less than the density of a first and/or may be configured to lift a first fluid to a fluid-lift portion.
Agency: NSF | Branch: Standard Grant | Program: | Phase: NSF INCLUDES | Award Amount: 32.41K | Year: 2016
The University of Georgia, Florida International University, Savannah State University, Clark Atlanta University and Fort Valley State University will lead this Design and Development Launch Pilot to address enhancing recruitment, retention, productivity and satisfaction of historically underrepresented minority (URM) undergraduate students who enroll in STEM graduate programs at primarily white (PWI) and research intensive (RI) universities. This project was created in response to the Inclusion across the Nation of Communities of Learners of Underrepresented Discoverers in Engineering and Science (NSF INCLUDES) program solicitation (NSF 16-544). The INCLUDES program is a comprehensive national initiative designed to enhance U.S. leadership in science, technology, engineering and mathematics (STEM) discoveries and innovations focused on NSFs commitment to diversity, inclusion, and broadening participation in these fields. The INCLUDES Design and Development Launch Pilots represent bold, innovative ways for solving a broadening participation challenge in STEM.
The full participation of all of Americas STEM talent is critical to the advancement of science and engineering for national security, health and prosperity. Our nation is advancing knowledge and practices to address the STEM education practices for retaining and educating URM undergraduate STEM students at our nations research intensive universities (RIs). This project, NSF INCLUDES: An Integrated Approach to Retain Underrepresented Minority Students in STEM Disciplines, has the potential to advance a collaborative approach by a group of organizations to improve the success of URM undergraduates in STEM disciplines.
The collaborating universities will work together for the purposes of empowering URM students to more effectively navigate STEM undergraduate and graduate education at minority serving institutions (MSIs) and PWIs, and for transforming the culture of PWIs and RIs. The team plans to use evidence-based approaches to gain insights into cultural differences that impact the success of URM STEM students. Three interventions will be included in the pilot study: (1) undergraduate URM student exchanges between MSIs and PWIs, (2) collaborative inquiry to engage URM students in social science research about issues and experiences of under-representation in STEM, and (3) the adaptation of resources from the Center for the Integration of Research, Teaching and Learning (CIRTL) to train STEM faculty to embrace diversity and improve teaching in diverse classroom settings. The project team plans to develop strategies to scale approaches and develop an alliance of institutions to maximize potential project outcomes.
Agency: NSF | Branch: Standard Grant | Program: | Phase: ROBERT NOYCE SCHOLARSHIP PGM | Award Amount: 1.42M | Year: 2014
For this Robert Noyce Teacher Scholarship Phase I project, investigators from Savannah State University (SSU) will work closely with partner institutions to recruit, mentor, educate, and certify students to become highly qualified STEM middle school and high school teachers to help alleviate workforce shortages in this area of national need. The project team will help place graduates from the program in high-need schools and then provide them with important and timely support when they enter the STEM teaching profession. Responding to the high demand for STEM teachers in the Savannah Chatham County Public School System (SCCPSS), SSU will partner with SCCPSS and two-year school Savannah Technical College (STC) to increase the number of high quality, technology education-certified STEM teachers prepared to teach in high-need schools. In particular, this Noyce project will prepare at least twenty-eight (28) undergraduate mathematics and engineering majors and eight (8) STEM professionals to become certified middle school or high school teachers of mathematics and/or science grades 6 - 12. SSUs activities as a Historically Black University with a student body of 94% African-American not only will enhance STEM workforce diversity, but will also contribute to a broader understanding of how teacher preparation programs can be tailored to reach and prepare African-American and other underrepresented minority students for successful STEM teaching careers.
The overall program will employ several interconnected components to recruit, train, mentor, and retain new highly qualified STEM teachers. These strategical components will include: (i) promoting extensive outreach and targeted recruitment activities; (ii) providing internships and summer programs (workshops, observation, and hands-on teaching experiences) for first and second year undergraduates as part of the recruitment process to generate interest in teaching; (iii) funding scholarships for selected junior and senior STEM majors who wish to become teachers; (iv) offering a challenging, problem solving, inquiry based, collaborating learning environment to address real-world applications through SSUs established teacher education program; (v) implementing field experience activities to aid the training and retaining process; (vi) orchestrating professional development, mentoring opportunities, and other induction support to ensure a successful transition to teaching and improved retention for the early career teacher graduates; and (vii) researching and assessing the effects of these initiatives. The assessment tools are designed to provide both quantitative and qualitative information as a basis for research and continuous improvement of the program.
Agency: NSF | Branch: Continuing grant | Program: | Phase: EDUCATION/HUMAN RESOURCES,OCE | Award Amount: 115.76K | Year: 2015
Savannah State University in Savannah, Georgia hosts an 8-week, 10-student summer Research Experience for Undergraduates (REU) program in marine sciences. The goal of this REU program is the early recruitment and support of undergraduate students in the STEM pipeline. This program is developed around a multidisciplinary, collaboration between academic and governmental partners in the Savannah, Georgia area. Savannah State Universitys local partners include the Skidaway Institute of Oceanography, UGA MAREX Aquarium and Grays Reef National Marine Sanctuary. Each has experienced research mentors and high level research facilities that provide an excellent environment for student research projects. Students receive a combination of classroom instruction, career guidance and research experience that is designed to support their continued progress in obtaining STEM degrees. NSF funding supports the student stipend and living expenses, limited research expenses for each student and program administration.
Agency: NSF | Branch: Standard Grant | Program: | Phase: HIST BLACK COLLEGES AND UNIV | Award Amount: 399.55K | Year: 2015
The Historically Black Colleges and Universities Undergraduate Program (HBCU-UP) through Targeted Infusion Projects supports the development, implementation, and study of evidence-based innovative models and approaches for improving the preparation and success of HBCU undergraduate students so that they may pursue STEM graduate programs and/or careers. The project at Savannah State University seeks to develop and implement an interdisciplinary undergraduate certificate program to educate students, including those from populations traditionally underrepresented in STEM disciplines, in technical, logistical, policy, research, and commerce-related issues of the transportation industry. Certificate recipients will be prepared to obtain career positions within the transportation industry, and thus help the U.S. economy remain competitive. The recruitment efforts include reaching out to high school students and exposing them to STEM subjects and their relationship to the transportation field.
The project has the following three goals: 1) to strengthen existing curriculum content associated with transportation concepts to better prepare students for transportation careers; 2) to increase awareness, student enrollment, and retention in transportation studies and associated fields such as logistics, civil engineering, and homeland security; and 3) to develop and implement student and faculty enhancement programs, specifically related to transportation studies. The activities and strategies are evidence-based and a strong plan for formative and summative evaluation is part of the project.