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Savannah, GA, United States

Savannah State University is a four-year, state-supported, historically black university located in Savannah, Georgia. Savannah State is the oldest public historically black university in Georgia. Savannah State University's mission statement is "to graduate students who are prepared to perform at higher levels of economic productivity, social responsibility, and excellence in their chosen career fields of endeavor in a changing global community.". The University is a member-school of Thurgood Marshall College Fund.Savannah State operates three colleges and the Office of Graduate Studies and Sponsored Research . It also participates in research centers and programs . Wikipedia.

Lofland D.,Savannah State University
Clinical laboratory science : journal of the American Society for Medical Technology

Clostridium difficile infection (CDI) results in clinical manifestations ranging from mild diarrhea to life-threatening pseudomembranous colitis. Infection is most often initiated by antimicrobial therapy which causes an imbalance in normal colonic microflora. The pathogenesis of C. difficile is predominantly controlled by the production of its two cytotoxins, A and B, which damage the intestinal mucosa. In recent years a nationwide increase in the rate of CDI has been noted as well as an increase in mortality, reduced initial response to antimicrobials, extended resolution time, and increased rates of recurrence. Traditional treatment includes administration of antimicrobials. Fecal microbiota transplant (FMT) is an alternative therapy for CDI that is effective and promising in multiple CDI relapse patients. This paper will provide an overview of CDI epidemiology, pathogenesis, diagnosis, and treatment, and explore the case of a 53-year-old woman suffering from her sixth episode of CDI. Source

Zhao H.,Savannah State University
Journal of Chemical Technology and Biotechnology

Ionic liquids (ILs) have evolved as a new type of non-aqueous solvents for biocatalysis, mainly due to their unique and tunable physical properties.Anumber of recent review papers have described a variety of enzymatic reactions conducted in IL solutions; on the other hand, it is important to systematically analyze methods that have been developed for stabilizing and activating enzymes in ILs. This review discusses the biocatalysis in ILs from twounique aspects (1) factors that impact the enzyme's activity and stability, (2)methods that have been adopted or developed to activate and/or stabilize enzymes in ionic media. Factors that may influence the catalytic performance of enzymes include IL polarity, hydrogen-bond basicity/anion nucleophilicity, IL network, ion kosmotropicity, viscosity, hydrophobicity, the enzyme dissolution, and surfactant effect. To improve the enzyme's activity and stability in ILs, major methods being explored include the enzyme immobilization (on solid support, sol-gel, or CLEA), physical or covalent attachment to PEG, rinsing with n-propanolmethods (PREP and EPRP), water-in-ILmicroemulsions, IL coating, and the design of enzyme-compatible ionic solvents. It is exciting to notice that new ILs are being synthesized to be more compatible with enzymes. To utilize the full potential of ILs, it is necessary to further improve these methods for better enzyme compatibility. This is what has been accomplished in the field of biocatalysis in conventional organic solvents. © 2010 Society of Chemical Industry. Source

Zhao H.,Savannah State University | Baker G.A.,University of Missouri
Journal of Chemical Technology and Biotechnology

During the past decade, ionic liquids (ILs) have gained tremendous attention in nearly every branch of the chemical and physical sciences as designer (task-driven) and budding 'green' solvent alternatives to conventional volatile organics. In particular, with a more in-depth understanding of their physicochemical properties, the active exploration of ILs as alternative solvents and/or catalysts in the chemical or enzymatic (biocatalytic) production of biodiesel has gained momentum. Most excitingly, very recent developments in the science of deep eutectic solvents (DESs) have initiated potentially more cost-effective approaches to biodiesel synthesis. At this stage, there is sufficient research completed to provide an important opportunity to stand back and assess the progress in the field, critically examining the strengths and limitations for IL and DES technology in biodiesel synthesis. No such comprehensive evaluation exists. This work, therefore, seeks to bridge this gap by systematically reviewing the reported methods for biodiesel production which make use of ILs, either as (co)solvent components or catalysts, highlighting existing problems and limitations, with an emphasis placed on the future research required to bypass the hurdles to employing ILs in commercial biodiesel production. © 2012 Society of Chemical Industry. Source

Agency: NSF | Branch: Standard Grant | Program: | Phase: HIST BLACK COLLEGES AND UNIV | Award Amount: 399.55K | Year: 2015

The Historically Black Colleges and Universities Undergraduate Program (HBCU-UP) through Targeted Infusion Projects supports the development, implementation, and study of evidence-based innovative models and approaches for improving the preparation and success of HBCU undergraduate students so that they may pursue STEM graduate programs and/or careers. The project at Savannah State University seeks to develop and implement an interdisciplinary undergraduate certificate program to educate students, including those from populations traditionally underrepresented in STEM disciplines, in technical, logistical, policy, research, and commerce-related issues of the transportation industry. Certificate recipients will be prepared to obtain career positions within the transportation industry, and thus help the U.S. economy remain competitive. The recruitment efforts include reaching out to high school students and exposing them to STEM subjects and their relationship to the transportation field.

The project has the following three goals: 1) to strengthen existing curriculum content associated with transportation concepts to better prepare students for transportation careers; 2) to increase awareness, student enrollment, and retention in transportation studies and associated fields such as logistics, civil engineering, and homeland security; and 3) to develop and implement student and faculty enhancement programs, specifically related to transportation studies. The activities and strategies are evidence-based and a strong plan for formative and summative evaluation is part of the project.

Agency: NSF | Branch: Continuing grant | Program: | Phase: EDUCATION/HUMAN RESOURCES,OCE | Award Amount: 115.76K | Year: 2015

Savannah State University in Savannah, Georgia hosts an 8-week, 10-student summer Research Experience for Undergraduates (REU) program in marine sciences. The goal of this REU program is the early recruitment and support of undergraduate students in the STEM pipeline. This program is developed around a multidisciplinary, collaboration between academic and governmental partners in the Savannah, Georgia area. Savannah State Universitys local partners include the Skidaway Institute of Oceanography, UGA MAREX Aquarium and Grays Reef National Marine Sanctuary. Each has experienced research mentors and high level research facilities that provide an excellent environment for student research projects. Students receive a combination of classroom instruction, career guidance and research experience that is designed to support their continued progress in obtaining STEM degrees. NSF funding supports the student stipend and living expenses, limited research expenses for each student and program administration.

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