Vidisha, India
Vidisha, India

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Khan H.,S.A.T.I. | Shukla R.N.,S.A.T.I. | Bajpai A.K.,Robertson College, Jabalpur
Materials Science and Engineering C | Year: 2016

The aim of the present investigation was to design biocompatible gelatin nanoparticles, capable of releasing the cytarabine drug in a controllable way by regulating the extent of swelling of nanoparticles. In order to achieve the proposed objectives, gelatin (Type A, derived from acid cured tissue) was modified by crosslinking with genipin and nanoparticles of crosslinked gelatin were prepared using single water in oil (W/O) emulsion technique. The nanoparticles were characterized by techniques like FTIR, SEM, TEM, particles size analysis, and surface potential measurements. The nanoparticle chemical architecture was found to influence drug-releasing capacity. The influence of experimental conditions such as pH and simulated physiological fluids as the release medium was also investigated on the release profiles of cytarabine. It is possible to fabricate high-performance materials, by designing of controlled size gelatin nanoparticles with good biocompatible properties along with desired drug release profiles. © 2015 Elsevier B.V. All rights reserved.


PubMed | Robertson College, Jabalpur and S.A.T.I.
Type: | Journal: Materials science & engineering. C, Materials for biological applications | Year: 2016

The aim of the present investigation was to design biocompatible gelatin nanoparticles, capable of releasing the cytarabine drug in a controllable way by regulating the extent of swelling of nanoparticles. In order to achieve the proposed objectives, gelatin (Type A, derived from acid cured tissue) was modified by crosslinking with genipin and nanoparticles of crosslinked gelatin were prepared using single water in oil (W/O) emulsion technique. The nanoparticles were characterized by techniques like FTIR, SEM, TEM, particles size analysis, and surface potential measurements. The nanoparticle chemical architecture was found to influence drug-releasing capacity. The influence of experimental conditions such as pH and simulated physiological fluids as the release medium was also investigated on the release profiles of cytarabine. It is possible to fabricate high-performance materials, by designing of controlled size gelatin nanoparticles with good biocompatible properties along with desired drug release profiles.


Purushottam,R.A.U.M. | Saxena K.,S.A.T.I. | Sharma R.,Amity University
International Conference on Computing, Communication and Automation, ICCCA 2015 | Year: 2015

Cardiovascular disease (CVD) is a big reason of morbidity and mortality in the current living style. Identification of Cardiovascular disease is an important but a complex task that needs to be performed very minutely, efficiently and the correct automation would be very desirable. Every human being can not be equally skillful and so as doctors. All doctors cannot be equally skilled in every sub specialty and at many places we don't have skilled and specialist doctors available easily. An automated system in medical diagnosis would enhance medical care and it can also reduce costs. In this study, we have designed a system that can efficiently discover the rules to predict the risk level of patients based on the given parameter about their health. The rules can be prioritized based on the user's requirement. The performance of the system is evaluated in terms of classification accuracy and the results shows that the system has great potential in predicting the heart disease risk level more accurately. © 2015 IEEE.


Samal M.K.,Bhabha Atomic Research Center | Balakrishnan K.S.,Bhabha Atomic Research Center | Parashar J.,SATI | Tiwari G.P.,Bhabha Atomic Research Center
Transactions of the Indian Institute of Metals | Year: 2014

Specimens machined in the form of circular rings directly from the nuclear reactor pressure tubes and tested in a ring-tension test-setup offer great simplicity in evaluating the transverse mechanical properties of the as-manufactured as well as those of the service-exposed tubes. However, the state of stress in the specimen cross-section is not purely uni-axial due to the effect of bending and the presence of lateral pressure due to the loading mandrel. This requires the use of 3-D finite element (FE) analysis for simulation of deformation behavior of the specimens in the ring-tension test-setup. In this work, we have analyzed the deformation behavior of ring-tension specimens machined from two different types of zirconium alloy pressure tubes as used in the Indian pressurized heavy water reactors. The effect of geometry of the loading mandrel (i.e., 2-piece vs. 3-piece type of mandrel) on the load-deformation behavior of the test-setup has been studied. It was observed that the values of maximum load as well as the deformation behavior in the post-necking region differ significantly when only the geometry of the loading mandrel is changed keeping all the other parameters same. FE analysis has been able to correctly predict these variations as it takes into account of the effect of geometry, material properties as well the interaction between the mandrel and the specimen. Hence, the use of FE method is essential in the inverse analysis procedure where the material properties can be determined from these complex test-setups. © 2013 Indian Institute of Metals.


Pandey G.S.,RGPV | Jain R.C.,SATI
Proceedings of the 2014 International Conference on Advances in Computing, Communications and Informatics, ICACCI 2014 | Year: 2014

The protein structure has always been under significant exploration, as this is vitally responsible for the basic functionality. Understanding the formation of these structures has gradually been called as 'the protein folding problem'. The solution for this problem is basically concerned with the ultimate aim to attain the native state. Broadly the methods to predict the ultimate goal, are categorized as- the template -based (homology modeling, threading/fold recognition) and template -free (ab initio) methods, which are discussed later in detail. In this paper, we have followed the ab initio methodology, to develop an ARTNN based approach to cluster the stable folds, out of the search space. The approach implemented through either of the two models (SF-ART or FC-ART model) could help enhance the performance of obtaining the three dimensional native state by providing more productive pathway, using the crude ab initio parameters, emphasizing quality performance with reduced execution time. This could thus be considered as a productive ab initio- clustering approach. © 2014 IEEE.


Sharma B.,S.A.T.I. | Chugh S.,S.A.T.I. | Jain V.,S.A.T.I.
Proceedings - 2014 4th International Conference on Communication Systems and Network Technologies, CSNT 2014 | Year: 2014

Routing protocols are required in network for deliver packets from source to destination. The multipath routing providing concept of load balancing but not efficiently distribute the load in network by that the valuable source of communication i.e. energy are affected from it because of packet loss. This paper work is motivated by the idea of taking account of several factors in Mobile Ad hoc Networks (MANET) routing design in a unified way. The rational of our motivation is that most of the multipath routing protocols are designed only based on one criterion, e.g., shortest path considered with balance load or energy conservation. We propose a scheme which could consider energy conservation, shortest path and load balancing, In this routing scheme, we would consider both the shortest path and the energy conservation in multipath way with proposed energy based multipath routing (E-AOMDV). We define an energy factor as that we will use the products of the energy factors of all the nodes along different paths as the selection criteria. The energy factor informs about the status of energy then here we evaluate the performance of AOMDV and energy based AOMDV (E-AOMDV). The life times of proposed E-AOMDV are limited but the improved routing as compare to AOMDV without including the energy factor. The performance of proposed scheme are better in limited life time. The performance matrices are shown the better results in proposed scheme. © 2014 IEEE.


Dehariya V.K.,S.A.T.I. | Shrivastava S.K.,S.A.T.I. | Jain R.C.,S.A.T.I.
Proceedings - 2010 International Conference on Computational Intelligence and Communication Networks, CICN 2010 | Year: 2010

Clustering or data grouping is a key initial procedure in image processing. In present scenario the size of database of companies has increased dramatically, these databases contain large amount of text, image. They need to mine these huge databases and make accurate decisions in short durations in order to gain marketing advantage. As image is a collection of number of pixels. It is difficult to take account of all pixels for clustering. So the concept of image segmentation play very useful role in clustering as it save times and it is efficient too. With the use of k-mean and it's variant fuzzy k-means algorithm clustering of these large data become easy and time saving. This paper deals with the application of standard k-means and fuzzy k-means clustering algorithms in the area of image segmentation. In order to assess and compare both versions of k-means algorithm and fuzzy k-means, appropriate procedures implemented. Experimental results point that fuzzy logically optimized k-means algorithms proved their usefulness in the area of image analysis, yielding comparable and even better segmentation results. © 2010 IEEE.


Mehto A.,SATI | Mehra N.,SATI
Procedia Computer Science | Year: 2016

This paper, presents a robust, secure and lossless digital image watermarking based on DWT and DCT. The combined DWT-DCT algorithm embedded watermarks in original medical image. It embeds watermark like patient's name, disease's name, hospital's name, and doctor's signature into original medical image. This watermarking algorithm provides privacy of patient. Many performance factors are considered to evaluate the performance parameters of the proposed scheme. The performance evolution factors include PSNR, and measuring their correlation with degradation of the whole image. © 2016 The Authors.


Yadav S.,S.A.T.I | Sain D.,S.A.T.I
Proceedings of the 2013 International Conference on Green Computing, Communication and Conservation of Energy, ICGCE 2013 | Year: 2013

Semantic similarity of the words is used specially in searching operations. Although there are various searching tools available for the searching of words, texts, images etc. But sometimes exact matching of the word doesn't require but the similar words having same meaning is required. Hence an efficient algorithm is implemented for the searching of semantic similarity between words. Here an efficient technique is implemented for the detection of similar words, as well as finding the frequency of word. © 2013 IEEE.


Kori N.K.,S.A.T.I. | Raghuwanshi S.,S.A.T.I.
Proceedings of the 2013 International Conference on Green Computing, Communication and Conservation of Energy, ICGCE 2013 | Year: 2013

The proper key management for the multicasting supported networks is one of the most important considerations to maintain the security of the network while reducing the overhead and storage requirements. The multicasting is used for communicating with a group of users from large number of users the most common application of the multicasting internet TV and online streaming. This paper presents a simple, efficient and secure technique for key generation, distribution and storage for multicasting networks. Finally the proposed algorithm is simulated using mat-lab and compared with standard key management algorithm. The analysis of the simulated results shows that the proposed algorithm performs well. © 2013 IEEE.

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