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Thiagu G.,Sathayabama University | Dhanasekaran R.,Syed Ammal Engineering College
Journal of Theoretical and Applied Information Technology | Year: 2014

In switching power circuits, due to the rapid switching of high current and high voltage, interference emission is created a serious problem. With the increase in switching frequency, possibility of interference also increases. When the interference is strong enough, then it can affect the normal working of associated circuits also. Electric and magnetic fields exist in any operating electric circuit. The current flowing in the circuit generates a magnetic field. For such a current to flow, there must be a potential difference, which produces an electric field. These fields can exist in any substance, including a vacuum. If they are strong enough, they make it possible for one electrical device to affect another. When this occurs unintentionally, it is known as electromagnetic interference, commonly abbreviated as EMI and often simply called as 'noise'. © 2005 - 2014 JATIT & LLS. All rights reserved. Source

Krishnaveni S.,Sathayabama University
Journal of Theoretical and Applied Information Technology | Year: 2014

In this work, a study of MEMS (Micro electro mechanical system) and SUGAsR simulator is presented. A MEMS power switch is implemented and the insertion loss, return loss with respect to frequency and ON and Off states of these loss with respect to frequency is studied. Ultra low ON state insertion loss, high off state isolation and high RF signal power handling characteristics are achieved .Many of the inherent problems associated with the more traditional switches is overcome with this power MEMS switch. The SUGAR simulator is used to obtain the performance analysis of the MEMS power switch. © 2005 - 2014 JATIT & LLS. All rights reserved. Source

Thiagu G.,Sathayabama University | Dhanasekaran R.,Syed Ammal Engineering College
International Journal of Applied Engineering Research | Year: 2014

The EMI problems are normally treated with cut and try process. In this paper, the conducted EMI noise is first modeled to get a full understanding of the EMI mechanism. The resulting model therefore provides a basic method for evaluating the effects of common EMI filter issues. The analysis and results proposed here can provide a guideline for future effective filtering schemes for switch mode power supplies. © Research India Publications. Source

Ramalingam G.,Sathayabama University | Prasad S.S.,Loyola College | Madhavan J.,Loyola College
AIP Conference Proceedings | Year: 2012

The Synthesis and characterization of CdSe/ZnSe nanocomposite was successfully achieved by adding CTAB and L-Cysteine. The XRD pattern and EDAX spectrum confirmed the formation of CdSe/ZnSe nanocomposite. The TEM photograph showed the presence of nanorods with a major population of prolonged nanorods as well as a minor population of spherical shape nanoparticles. The obtained nanorods diameter is 50-70 nm and the length is 150-175 nm. The SAED pattern of nanorods shows a superimposed good crystalline in nature. The UV and PL experiments confirmed the relative shift of composite nanostructure. © 2012 American Institute of Physics. Source

Kandakatla N.,Sathayabama University | Ramakrishnan G.,Sathayabama University | Chekkara R.,Sathayabama University | Balakrishnan N.,Bharathidasan University
Frontiers in Biology | Year: 2014

Niemann-Pick disease type C1 (NPC1), caused by mutations of NPC1 gene, is an inherited lysosomal lipid storage disorder. Loss of functional NPC1 causes the accumulation of free cholesterol (FC) in endocytic organelles that comprised the characteristics of late endosomes and/or lysosomes. In this study we analyzed the pathogenic effect of 103 nsSNPs reported in NPC1 using computational methods. R1186C, S940L, R958Q and I1061T mutations were predicted as most deleterious and disease associated with NPC1 using SIFT, Polyphen 2.0, PANTHER, PhD-SNP, Pmut and MUTPred tools which were also endorsed with previous in vivo experimental studies. To understand the atomic arrangement in 3D space, the native and disease associated mutant (R1186C, S940L, R958Q and I1061T) structures were modeled. Quantitative structural and flexibility analysis was conceded to observe the structural consequence of prioritized disease associated mutations (R1186C, S940L, R958Q and I1061T). Accessible surface area (ASA), free folding energy (FFE) and hydrogen bond (NH bond) showed more flexibility in 3D space in mutant structures. Based on the quantitative assessment and flexibility analysis of NPC1 variants, I1061T showed the most deleterious effect. Our analysis provides a clear clue to wet laboratory scientists to understand the structural and functional effect of NPC1 gene upon mutation. © 2014, Higher Education Press and Springer-Verlag Berlin Heidelberg. Source

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