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Karimnagar, India

Satavahana University is a public university situated in Karimnagar in Telangana. Wikipedia.


Dayakar G.,Kakatiya University | Jeyanthi A.,Satavahana University
Der Pharma Chemica | Year: 2013

3H-imidazo[4,5-b]pyridine-2-amine(2) was treated with acetyl acetone to form 1-(3H-imidazo[4,5-b]pyridine-2-yl)-2-(pentan-2,4-dione-2-ylidene)hydrazine(3). This was treated with hydrazine hydrate and phenyl hydrazine hydrate to give pyrrole derivatives 1-(3H-imidazo[4,5-b]pyridine-2-yl)-2-(3,5-dimethyl-1H-pyrrol-2-yl)diazenes(4,5). Source


Dayakar G.,Kakatiya University | Jeyanthi A.,Satavahana University
Der Pharma Chemica | Year: 2013

Oxadiazole, Tetrazole and Thiadiazole derivatives of 1H-Imidazo[4,5-b]pyridine are synthesized by using simple reagents like I2/KI, NaOH, H2SO4 in an efficient manner. The structures of the synthesized compounds are analysed by IR, 1HNMR and Mass spectra. Source


Nayak A.S.,Satavahana University
International Journal of Pharma and Bio Sciences | Year: 2014

A new series of 2,5-disubstituted 1,3,4-thiadiazoles were synthesized by using different aromatic or aliphatic carboxylic acids (1) and thiosemicarbazide (2). The structures of the synthesized compounds were established by their spectral (IR, 1H NMR and Mass) data. All the compounds were screened for their antimicrobial activity against Staphylococcus aureus. Escherichia coli, Compounds showed mild to moderate activity, but not comparable with the standard (Norflaxacin). Source


Kankala S.,Kakatiya University | Vadde R.,Kakatiya University | Vasam C.S.,Satavahana University
Organic and Biomolecular Chemistry | Year: 2011

A first example of organo-N-heterocyclic carbene (NHC) catalyzed click-type fast 1,3-dipolar cycloaddition of nitrile oxides with alkynes was developed for the regioselective synthesis of 3,5-di- and 3,4,5-trisubstituted isoxazoles. Triethylamine (Et 3N) was employed as an effective base to generate both nitrile oxide and the organo-NHC catalyst in situ. This catalytic approach was used to attach a variety of substituents, including other biologically active fragments, onto the isoxazole ring to selectively design multinucleus structures. Further, we have also optimized the conditions for Cu(i)-free Sonogashira cross-coupling to obtain internal alkynes in high yields, which were subsequently used in cycloaddition. A catalytic cycle is proposed and the remarkable regiocontrol in the formation of isoxazoles was ascribed to a beneficial zwitterion intermediate developed by the interaction of the strongly nucleophilic organo-NHC catalyst with alkyne followed by nitrile oxide. © 2011 The Royal Society of Chemistry. Source


Kankala S.,Kakatiya University | Edulla R.,Kakatiya University | Modem S.,Kakatiya University | Vadde R.,Kakatiya University | Vasam C.S.,Satavahana University
Tetrahedron Letters | Year: 2011

The intramolecular crossed aldehyde-ketone benzoin condensation in the chalcone of o-phthalaldehyde (OPA) catalyzed by N-heterocyclic carbene (NHCs) generated in situ from readily available imidazolium and thiazolium salts is described. In this reaction, bicyclic α-hydroxyl ketones (naphthalenone type tertiary alcohol) were selectively produced in good yields (75-94%) in shorter reaction times (20 min) through nucleophilic addition of acyl anion generated by umpolung in OPA-chalcone (regio controlled). © 2011 Elsevier Ltd. All rights reserved. Source

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