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Stiukhina E.S.,N.G. Chernyshevsky | Kurochkin M.A.,N.G. Chernyshevsky | Klochkov V.A.,Saratov Scientific Research Institute of Cardiology | Fedosov I.V.,N.G. Chernyshevsky | Postnov D.E.,N.G. Chernyshevsky
Progress in Biomedical Optics and Imaging - Proceedings of SPIE | Year: 2014

A method is presented to obtain information on tissue perfusability from capillary velocimetry experiments coupled with venous occlusion probe. The method based on data fitting to developed mathematical model describing the blood flow redistribution caused by the introduced occlusion. Using mathematical modeling, we identify the segment of velocity time courses that corresponds to tissue swelling process and thus allows ones quantify it. We also compared the results of direct measurement of red blood cells (RBCs) velocity with time courses obtained from finger-placed sensors of two types: (i) photoplethysmographic sensor used in pulsometry and (ii) piezoelectric sensor for sphygmography. The obtained results suggest the measurable contribution of RBCs aggregation process in optical pulse signal formation. © 2015 SPIE.

Tsoy M.O.,Chernyshevsky Saratov State University | Stiukhina E.S.,Chernyshevsky Saratov State University | Klochkov V.A.,Saratov Scientific Research Institute of Cardiology | Postnov D.E.,Chernyshevsky Saratov State University
Progress in Biomedical Optics and Imaging - Proceedings of SPIE | Year: 2014

The elimination of low-frequency noise of breath and motion artifacts is one of the most difficult challenges of preprocessing rheographic signal. The data filtering is the conventional way to separate useful signal from noise and interferences. Conventionally, linear filtering is used to easy design and implementation. However, in some cases such techniques are difficult, if possible, to apply, since the data frequency range is overlapped with one of interferences. Specifically, it happens in aortic rheography, where some breathing process and pulmonary blood flow contributions are unavoidable. We suggest an alternative approach for breathing interference reduction, based on adaptive reconstruction of baseline deviation. Specifically, the computational scheme based on multiple calculation of Akima splines is suggested, implemented using C# language and validated using surrogate data. The applications of proposed technique to the real data processing deliver the better quality of aortic valve opening detection. © 2015 SPIE.

Furman N.V.,Saratov Scientific Research Institute of Cardiology | Graifer I.V.,Saratov Scientific Research Institute of Cardiology | Reshetko O.V.,Saratov Scientific Research Institute of Cardiology | Dolotovskaya P.V.,Saratov Scientific Research Institute of Cardiology
Kardiologiya | Year: 2013

Aim of the study was to elucidate gender related characteristics of clinical status and treatment of patients with atrial fibrillation (AF) hospitalized in a department of urgent cardiology of multiprofile clinical hospital. In a retrospective pharmacoepidemiological study we analyzed case histories of 114 men and 79 women hospitalized because of detected and electrocardiografically confirmed paroxysmal or persistent AF. Compared to men women were significantly older, among them there were significantly more individuals older than 75 years (p<0.05), and AF developed in women at older age (p<0.05). However duration of arrhythmic anamnesis was similar in women and men. Among women we noted greater prevalence of ischemic heart disease; they had higher risk of thromboembolic complications and higher rate of these complications in anamnesis. Rates of obesity and diabetes mellitus were also higher among women. Men more often had isolated arterial hypertension and lung diseases. There were more smokers among men. Women significantly less often received adequate antithrombotic therapy; they were less often subjected to electrical cardioversion. Rate control strategy was more often selected for women.

Kiselev A.R.,Saratov Scientific Research Institute of Cardiology | Khorev V.S.,Chernyshevsky Saratov State University | Gridnev V.I.,Saratov Scientific Research Institute of Cardiology | Prokhorov M.D.,Russian Academy of Sciences | And 5 more authors.
Human Physiology | Year: 2012

Biophysical features of 0.1-Hz oscillations of heart rate variability (HRV) and distal blood flow (DBF) variability were compared in healthy subjects and patients after acute myocardial infarction (MI). Patients with acute MI (72 men and 53 women; 125 in total) and healthy subjects (23 men and 10 women; 33 in total) aged 30-83 and 20-46 years, respectively, participated in the study. The patients were involved in the study for a year after acute MI. The delay in coupling 0.1-Hz oscillations of HRV and DBF variability was estimated. In healthy subjects, the delay in the heart → DBF coupling proved to be less than the delay in the DBF → heart coupling. Acute MI results mainly in disruption of the heart → DBF coupling, which is partially restored by the end of the first year after acute MI, though it remains lower than in healthy subjects. The DBF → heart coupling is rapidly restored to the level of healthy subjects within three weeks after acute MI. © 2012 Pleiades Publishing, Ltd.

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