Dwivedi N.,Saraswati Dental College and Hospital |
Raj V.,Saraswati Dental College and Hospital |
Chandra S.,Saraswati Dental College and Hospital
Indian Journal of Cancer | Year: 2013
Salivary gland tumors are one of the most complex and relatively rare group of lesions encountered in oral pathology practice. Their complexity is attributed to heterogeneity of the cells of origin of these lesions. The problem is compounded by the ability of these cells to differentiate and modify into various morphological subtypes resulting in a myraid of histomorphological patterns. This also leads to a frequent overlap of microscopic features among various neoplasms and sometimes even between benign and malignant lesions causing significant diagnostic dilemma which sometimes may even not be resolved by immunohistochemical studies. Despite this the knowledge of histogenesis and morhogenetic concepts of salivary gland tumorigenesis greatly helps the pathologist in classifying these lesions as well as determining the prognosis. It will also help in development of newer strategies for differentiating these lesions and making an early diagnosis. The present article is aimed at reviewing and summarizing the current concepts regarding the histogenesis of salivary gland tumors and their relevance to routine diagnosis and classification of these lesions.
PubMed | Saraswati Dental College and Hospital and Dental College and Research Center
Type: Journal Article | Journal: The journal of contemporary dental practice | Year: 2017
This research analyzed the influence of television on the behavior of children belonging to urban and rural socioeconomic backgrounds of Bhopal city and its vicinity.About 400 parents with children between 1 and 18 years of age were subjected to a self-designed questionnaire, which sought information regarding the television viewing habits of children. Differences in responses were noted between the subjects of urban and rural areas. Obtained data were subjected to statistical analysis using Pearsons chi-square test to determine the level of significance.The urban class showed a dominating pattern in the positive aspects of television viewing, such as significantly better awareness of oral health, more emphasis shown toward oral care adverts, and a higher knowledge of the cause of dental caries. However, the urban class also possessed a poor attitude; the appearance of a dentist on television did not remind them about oral needs, products with gifts pleased their children to a greater extent, they had more demanding children, parents fulfilled their childrens demand more, and they relied on the self for selection of toothpaste. Overall, in all aspects, the rural class lacked significantly.Television exerts a positive as well as negative influence on childrens behavior among urban and rural communities, with the influence being more obvious in the urban class.The results of this study can be utilized in bringing about better and effective advertising oriented toward attaining optimum oral health of children; overall general health through adverts that discourage obesogenic diet and promote a diet rich in protein and fiber can also be focused on.
Garg K.,Chandra Dental College and Hospital |
Raj V.,Saraswati Dental College and Hospital |
Chandra S.,King College
Journal of Oral and Maxillofacial Pathology | Year: 2013
Background: Oral cancer is one of the most debilitating and disfiguring of all malignancies; it is one of the most frequently occurring cancers in the body. The high incidence of oral cancer in India has been attributed to widespread tobacco usage among the population either in chewable or smoked form. Aim: In the current study, we retrospectively analyzed 191 cases (2007-2009) of potentially malignant oral lesions, which had been biopsied in our hospital, in order to assess their relationship with tobacco usage. Materials and Methods: Based on the histopathology, these lesions were classified as high-risk lesions (HRL), low-risk lesions, and questionable risk lesions. The data obtained were then analyzed to find out the correlation between the occurrence of risk level with various demographic parameters such as age and gender as well as with type, frequency, and duration of tobacco habit. Results: Out of 191 cases, 122 patients reported with tobacco habit (chewers, smokers, and both) and frequency (<5 and >5 packets/day) were seen in 109 cases and duration (<5 and >5 years) seen in 99 cases. These parameters were correlated with histopathological diagnosis and results showed that both the groups came under the high-risk category. Further analysis of decategorized group (age and gender) was also done. Conclusion: Analysis showed that overall histopathologically diagnosed HRLs were seen more in males and smokers compared to female and chewers, respectively.
Makker A.,Central Drug Research Institute |
Makker A.,University of Lucknow |
Singh M.M.,Central Drug Research Institute |
Singh M.M.,Saraswati Dental College and Hospital |
And 5 more authors.
Menopause | Year: 2012
Objective: Postmenopausal osteoporosis is one of the most common metabolic bone disorders. Osteoporosis is reported to cause bone loss in the alveolar processes of maxilla and mandible, which provide bony framework for tooth anchorage. However, the association between systemic osteoporosis and oral health remains controversial. Available evidence suggests that Indian women have lower peak bone mass than their Western/other Asian counterparts. The present study evaluated the relationship between mandibular bone mineral density (mBMD), systemic skeletal BMD, and bone metabolism in premenopausal and postmenopausal Indian women. Methods: One hundred twenty-four premenopausal and 247 postmenopausal healthy women were included in the study. The BMD of the body of mandible, radius ultradistal, total hip, femur neck, and lateral spine were measured using dual-energy X-ray absorptiometry. Serum and urine biomarkers were determined using commercial kits. Results: Univariate regression analysis followed by stepwise multivariate regression analysis to obtain the best fit model demonstrated the BMD of radius ultradistal, serum inorganic phosphorus, estradiol, and sex hormone-binding globulin as significant predictors of mBMD in premenopausal women. The BMD of femur neck, serum ionized calcium, bone-specific alkaline phosphatase, osteocalcin, and urine total pyridinoline were significantly associated with mBMD in postmenopausal women. The significant association between mBMD and number of teeth present was observed in the whole group of premenopausal and postmenopausal women. Conclusions: Varied predictors of mBMD were observed in premenopausal and postmenopausal women. The results suggest that the screening for these biomarkers and serum ionized calcium should be useful (1) to assess the status of mBMD particularly in women requiring surgical dental intervention that include bone manipulation and (2) for early detection and management of women with the risk of developing osteoporosis. © 2012 by The North American Menopause Society.
Loomba K.,Saraswati Dental College and Hospital
Journal of oral science | Year: 2010
Accuracy in defining a disease makes it easier to study and understand. Similarly, with injuries to the teeth, a comprehensive classification is an aid to correct diagnosis and treatment planning. A thorough review of various classifications of tooth fractures shows that, despite an emphasis on traumatic dental injuries, a consensus needs to be arrived at, especially among clinicians and general/family dentists. The ideal classification would be applicable to both primary and permanent dentition, based on tooth fractures in both the horizontal and vertical planes, encompassing all possible sites, easy to comprehend, communicable amongst health professionals and clinically relevant. With recent improvements in conservative techniques, it is now clinically possible to preserve natural teeth even if they have been horizontally or vertically fractured, and thus an in-depth understanding and knowledge of tooth fractures, together with a simplified classification, is now more than ever essential.
Kashyap B.,Saraswati Dental College and Hospital |
Reddy P.S.,Saraswati Dental College and Hospital
Journal of Cancer Research and Therapeutics | Year: 2012
The micronuclei assay (MA) in exfoliated buccal cells is an innovative genotoxicity technique, which holds promise for the study of epithelial carcinogens. Micronuclei are suitable internal dosimeters for revealing tissue-specific genotoxic damage in individuals exposed to carcinogenic mixtures. This article reviews the MN assay with respect to oral buccal mucosa, which has been used since the 1980s to demonstrate cytogenetic effects of environmental and occupational exposures, lifestyle factors, dietary deficiencies, and different diseases along with the characteristics of micronuclei and other nuclear abnormalities.
Chandra S.,Saraswati Dental College and Hospital |
Raju S.,Saraswati Dental College and Hospital |
Sah K.,Saraswati Dental College and Hospital |
Anand P.,Saraswati Dental College and Hospital
Archives of Iranian Medicine | Year: 2014
Chronic ulcers of the oral mucosa are the lesions which a physician comes across frequently. "Eosinophilic Ulcer" is a rare variety of that. Eosinophilic ulcer or traumatic ulcerative granuloma with stromal eosinophilia (TUGSE) is a chronic benign lesion of the oral mucosa and is a relatively recent delineated entity. Its etiopathogenesis is still uncertain but trauma seems to play a fundamental role. Clinically the lesion manifests as an isolated ulcer, showing a raised and indurated border in addition to a white or yellowish bed. Microscopically, it is characterized by diffuse polymorphic inflammatory infiltrate, rich in eosinophils, involving the superficial mucosa and the deeper muscle layer with epitheliod cells. Hereby, reporting a case of a 60-year-old female patient who presented with a chief complaint of non-healing painful ulcer on the tongue.
Singh P.,Saraswati Dental College and Hospital |
Singh A.,Saraswati Dental College and Hospital
Journal of Oral and Maxillofacial Pathology | Year: 2013
Angiolymphoid hyperplasia with eosinophilia is a rare reactive, angio-proliferative lesion which is usually found in the subcutaneous tissue of the head and neck. The lesion rarely arises from a native blood vessel. It is of unknown etiology but may be related to some benign, localized form of vasculitis. While preauricular location is the most frequent site of occurrence as reported in literature, a lesion in submental region seems to be a first reported site of occurrence. We report such an occurrence in an individual with history of trauma twice in his lifetime at the affected site. Spontaneous regression is common, but persistent or recurrent lesions may require treatment. Several treatments have been reported but surgery is considered to be the most efficient one.
Bahuguna R.,Saraswati Dental College and Hospital |
Khan S.Y.,Saraswati Dental College and Hospital |
Jain A.,Saraswati Dental College and Hospital
European Journal of Paediatric Dentistry | Year: 2013
Aim The aim of this study was to investigate the relationship of feeding practices with dental caries in a group of respondents of 1-18 years of age of Lucknow city, India. Materials and methods A case-control study was carried out in the outpatient department of Paedodontics and Preventive Dental Clinic, Saraswati Dental College and Hospital, Lucknow (UP), India. A total sample of 800 subjects in the 1-18 years age group was equally divided among cases (DMFT/deft >0) and controls (DMFT/deft = 0). Cases matched with controls for age, sex and religion. Clinical examination (DMFT/deft index) was performed in accordance with the WHO criteria for epidemiological studies. Respondents were interviewed in depth and retrospectively by means of a self-administered questionnaire. Results Prolonged breast feeding beyond 6 months, bottle feeding, nocturnal bottle feeding containing sweet drink and milk and higher frequency of consumption of sweets emerged as significant risk factors for dental caries. Conclusion Based on the differences between the caries and non-caries age groups, an educational and preventive programme should be initiated addressing the associated risk factors of specific age groups accordingly. In our present study nocturnal bottle feeding emerged as the most significant risk factor for dental caries in the 1-6 years age group. Hence health professionals should recognise the benefits of breastfeeding up to six months of life and should educate mothers about the importance of implementing beneficial dental habits to ensure that a child reaches oral health.
PubMed | Saraswati Dental College and Hospital
Type: Journal Article | Journal: European journal of dentistry | Year: 2017
The objective of the study was to evaluate clinically and radiographically the efficacy of platelet-rich fibrin (PRF) versus -tri-calcium phosphate (-TCP) in the treatment of Grade II mandibular furcation defects.Forty-five Grade II furcation defect in mandibular molars which were assigned to open flap debridement (OFD) with PRF Group I (For clinical parameters, reduction in PPD and gain in VCAL and HCAL were higher in Group II as compared to Group I. Change in r-VHF and r-HDF was greater in Group II as compared to Group I. Mean percentage clinical vertical defect fill was higher in Group II as compared to Group I (58.52% 11.68% vs. 53.24% 13.22%, respectively). On CBCT, mean change at 6 months for all parameters showed nonsignificant difference between the two experimental groups. Mean change in V-HOF was higher in Group I as compared to Group II, but mean change in H-DOF and furcation width was more in Group II as compared to Group I.For both experimental and control groups, there was statistically significant improvement at 6 months follow-up from baseline values.