Saraswathi Institute of Medical science

Ghāziābād, India

Saraswathi Institute of Medical science

Ghāziābād, India
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Singh H.K.,Saraswathi Institute of Medical science
Medico-Legal Update | Year: 2012

Profiling of Medico legal cases will help authorities for planning, prevention and treatment of casualties. This Study was carried out on Medico legal cases reporting to casualty of SIMS Panchsheel Nagar in one year duration from 1st Jan. to 31st Dec.2009. The main objectives of the study were to analyze pattern and study demographic variables of Medico legal cases and suggest preventive measures which would possibly reduce incidence of these case. Out of total 583 cases 4 were brought dead so excluded from study. Males (76.51%) outnumbered the females and maximum cases were of age group 21-30 yrs. (32.10%) more cases from rural area(62.5%) were reported, April month saw maximum no of cases (11.6%), Maximum admission were done during office hours (50.3%), maximum no. of incidence was seen on NH-24(63.4%), RTA was the commonest mode of injury (71.50%). Lacerated wound was the commonest injury (23.49%) and more than one region of body was involved in maximum cases (36.6%). Lower limb bones were involved in 7.43% of cases. 79.10% cases were treated effectively and discharged.


Goel A.K.,Saraswathi Institute of Medical science
Clinical Rhinology | Year: 2017

Objectives: Adenoid hypertrophy is known as the most common cause of nasal obstruction in children; thus, adenoidectomy is one of the most commonly performed surgical procedures in the pediatric population. We performed both conventional and endoscopic-assisted adenoidectomies in 54 patients. Our objectives were to compare the efficacy of both methods in terms of subjective and objective relief of symptoms, safety, recurrence, and postoperative morbidity. Materials and methods: Fifty-four patients were studied and were diagnosed depending upon clinical examination and radiological investigation. The patients were operated by either conventional or endoscopic-assisted adenoidectomy (EAA). Intraoperative and postoperative complications were looked for. After discharge from the hospital, the patients were called for follow-up on 1st week, 3rd week, 2nd and 4th month, and patients were asked for relief of symptoms and examined for nasal disease and for recurrence. Results: Adenoid hypertrophy was seen commonly in children and the most common presenting complaints were nasal obstruction, mouth breathing, and snoring. The patients were diagnosed to have chronic adenoiditis, chronic adenotonsillitis, with or without chronic suppurative otitis media. More number of patients became symptom free with EAA as compared with conventional adenoidectomy. Conclusion: Conventional adenoidectomy and EAA both have comparable success rates. Endoscopic-assisted adenoidectomy allows complete removal of adenoid tissue, thereby reducing the chances of developing recurrent adenoid obstructive symptoms and reducing the bacterial reservoir in the nasopharynx. © 2017, Jaypee Brothers Medical Publishers (P) Ltd. All rights reserved.


Singh R.,Saraswathi Institute of Medical science | Singh H.K.,Saraswathi Institute of Medical science | Gupta S.C.,Saraswathi Institute of Medical science | Kumar Y.,Saraswathi Institute of Medical science
Indian Journal of Community Medicine | Year: 2014

Introduction: Expansion in road network, motorization, and urbanization in the country has been accompanied by a rise in road accidents leading to road traffic injuries (RTIs). Today RTIs are one of the leading causes of deaths, disabilities, and hospitalizations with severe socioeconomic costs across the world. Objectives: The following study analyses the: Age and sex distribution of injured in road traffic accidents (RTAs).Circumstances leading to RTA.Pattern and severity of injuries sustained in RTAs cases. Design: Retrospective record-based study. Materials and Methods: The aim of this study was to audit retrospectively the circumstances, severity, and pattern of injury sustained by vehicle occupants presenting to the Saraswathi Institute of Medical Sciences (SIMS) hospital Hapur, for a period of one year. Data were collected using the case sheets of 347 patients from the medical records section of hospital and analyzed using SPSS computer software version 16.0. Results are interpreted in terms of percentage, mean, chi-square, and z-test. Results: The pattern and severity of injuries sustained by 347 vehicle occupants admitted to the emergency department of SIMS, Hapur were retrospectively documented. Male victims 258 (74.35%) were more commonly involved than females 89 (25.65%) and majority of victims 141 (40.63%) were in age group of 20-30 years. Urban victims 222 (64.00%) outnumbered rural. The most frequently injured body regions were the extremities 499 (53.54%), followed by maxillofacial180(19.31%).. Out of total 802 external injuries, the most common type of injury was lacerations 307 (38.28%), abrasions 306 (38.15%)and followed by bruises 154 (19.20%). Multiple external injuries were more common on upper limb 216 (26.93%) , lower limbs 210 (26.18%) and face 170 (21.20%), while crush injuries were more predominently seen in both the limbs. While laceration were common on face 120 (38.83%). Injuries to the chest 19 (2.36%), abdomen13 (1.61%), and spine 11 (1.36%) were seen in roughy equal proprotion of victims. The bones on right side 55 (55.55%) were more commonly fractured which is statistically significant. Skull injuries were mostly found on frontal 77 (47.53%), followed by parietal bone 33 (20.37%), mostly on right side. Conclusion: RTAs constitute a major public health problem in our setting. Urgent preventive measures targeting at reducing the occurrence of RTAs are necessary to reduce the morbidity and mortality resulting from these injuries.


Jain S.,Saraswathi Institute of Medical science
Journal of Krishna Institute of Medical Sciences University | Year: 2016

Background: Shavasana is one of the most popular yogic exercises used for relaxation of body. Aim and Objectives: The present study was done to find out direct effect of Shavasana on cardiac output and peripheral resistance by using Impedance Cardiovasograph (Nivomon, Larsen & Toubro Medical's). Material and Methods: One hundred asymptomatic healthy male subjects, aged 17-23 years, participated voluntarily in the present study. Cardiac output, systemic peripheral resistance and other cardiovascular parameters were measured before and after Shavasana of 30 minutes. Results: Statistically significant decrement was observed in all cardiovascular parameters after shavasana but decrement was more pronounced in Diastolic Blood Pressure (DBP), Heart Rate (HR), Systemic Peripheral Resistance (SPR) and Systemic Vascular Resistance Index (SVRI) in comparison to decrement in Systolic Blood Pressure (SBP), Cardiac Output (CO), Stroke Volume (SV), Cardiac Index (CI), Stroke Volume Index (SI). Conclusion: The practice of Shavasana for short duration immediately improves cardiovascular parameters including cardiac output and systemic peripheral resistance which directly influence blood pressure and might be beneficial in normal subjects and hypertensive patients as well. © Journal of Krishna Institute of Medical Sciences University.


Sood N.,Deen Dayal Upadhyay Hospital | Nigam J.S.,Saraswathi Institute of Medical science
Pathology Research International | Year: 2014

Purpose. Triple-negative breast cancer (TNBC) is defined by the loss of expression of ER, PR, and Her2neu expressions. The aim of this study was to examine the expression of the EGFR, CK5, and Ki-67 among triple-negative breast cancer cases and to correlate the expression of the basal markers with the clinicopathological prognostic parameters. Materials and Methods. Thirty-six female patients with TNBC based on ER, PR, and the HER2neu negativities were studied by immunohistochemistry for EGFR, CK5, and Ki-67 expression. Statistical analysis was done using the SPSS software version 20. Results. The mean and median ages were 45.18 years and 46.70 years, respectively. Infiltrating ductal carcinoma NOS was the predominant histopathological type (29/36 [80.6%]). The commonest histological grade was grade 2 (17/36 [47.2%]). Tumour necrosis was seen in 16/36 (44.4%) patients. Infiltrative margins were shown in 69.44% (25/36) cases. Ki-67 was positive in 80.56% (29/36) cases, 61.11% (22/36) were CK5-positive, and 86.11% (31/36) were EGFR-positive. The only significant positive association observed was between the CK5 and histological grade (P<0.05). Conclusion. CK5 shows a statistically significantly correlation with TNBC histological grade. The majority of the specimens show EGFR expression. Therefore TNBCs could potentially benefit from EGFR-targeted therapeutic strategies. © 2014 Neelam Sood and Jitendra Singh Nigam.


Omhare A.,GSVM Medical College | Singh S.K.,Mlb Medical College | Nigam J.S.,Saraswathi Institute of Medical science | Sharma A.,Ddu Hospital
Pathology Research International | Year: 2014

Background. FNAC is a useful method for evaluating suspicious salivary glands lesions due to its low cost, minimum morbidity, rapid turnaround time, high specificity, and sensitivity. Aim. To knowthe frequency of the salivary gland lesions and cytohistological correlation in the Jhansi region, Uttar Pradesh, India. Material and Methods. In present study 124 cases were included and cytohistological correlation was made in 86 cases only. FNA was performed by using a 23/24-gauge needle without local anaesthesia. Air dried and 95% ethyl alcohol fixed wet smears were stained with Giemsa stain and Papanicolaou stain, respectively. Paraffin embedded tissue sections were stained with Haematoxylin and Eosin. Results. Parotid gland was the most commonly involved salivary gland. The commonest age group was 20 to 29 years, 30 to 39 years, and 60 to 69 years for nonneoplastic lesions, benign tumours, and malignant tumours, respectively.The overall male to female ratio was 1.17 : 1.The diagnostic accuracy of FNAC was 100%, 93.3%, and 88.2% for nonneoplastic lesions, benign tumours, and malignant tumours, respectively. Conclusion. The high accuracy, sensitivity, and specificity of FNAC confirmthat preoperative cytology is a useful, quick, reliable diagnostic technique for rapid diagnosis and suitable for developing countries. Copyright © 2014 Anita Omhare et al.


Kumar V.,Saraswathi Institute of Medical science | Gupta M.,Saraswathi Institute of Medical science
Indian Journal of Public Health Research and Development | Year: 2016

Indomethacin is commonly used as anti inflammatory, antipyretic and analgesic drug. Inflammation is characterized by redness, swelling, heat and pain. Indomethacin produces anti-inflammatory effects by decreasing the production of prostaglandins. Ingestion of Indomethacin may be associated with peptic ulcer formation. Present study was carried out over a period of twelve months on 16 adult Albino rats of Charles Foster strain (8 males and 8 females). The rats were randomly divided into 4 groups. Group 1st was taken as control and the remaining three were taken as the experimental groups. Each experimental group was subjected to oral administration of Indomethacin for 1, 2 and 3 weeks in Group I, II and III respectively. Rats of each group were dissected at the end of 1st, 2nd and 3rd week intervals after giving ether anesthesia. Duodenum was preserved and stained for histological examination. Height of villi, Numbers of goblet cells columnar cells and mitotic figure/HPF showed significant changes in experimental group in comparison to control group and were more pronounced in 2nd week. Findings of the study suggest histological changes occur after administration of Indomethacin which may be due to as a response to Indomethacin induced injury in the wall of duodenum of albino rats. © 2016, Indian Journal of Public Health Research and Development. All rights reserved.


Jain S.,Saraswathi Institute of Medical science
Indian Journal of Public Health Research and Development | Year: 2016

Obesity is major problem in present population especially in children and young adults. Obesity is a state of excess adipose tissue mass. Stress is inevitable in the present scenario. Obesity adversely affects almost all the systems of the body including cardiovascular and respiratory system and reduces exercise tolerance & stress tolerance. Exposure to sudden extreme stress is commonly seen in medical students. Therefore the present study was conducted to assess the effect of acute stress on cardiac output and systemic peripheral resistance in obese young adults. Sixty asymptomatic healthy male medical students, aged 17-25 years, participated voluntarily in the present study. Subjects were divided in to two groups of 30 each. Group A comprised of non- obese (BMI<25, control group) and group B comprised of obese subjects (BMI> 30). Cold pressor test (CPT) was used to induce acute stress which involves immersion of hand in cold water of 8oc for 2 minutes. Cardiac output and peripheral resistance were measured by using Impedance Cardiovasograph (Nivomon). All the parameters were recorded before and immediately after cold pressor test in both the groups. Results showed significant increase in cardiac output and systemic peripheral resistance (p<0.05) immediately after exposure to cold stress for two minutes in comparison to baseline parameters in both the groups, however this increase was more significant in group B (p<0.01) than control group (p<0.05). On comparison of parameters before CPT and 5 minutes after CPT, no significant difference was observed in parameters including cardiac output and systemic peripheral resistance (P>0.05) in control group but these were significantly higher in obese subjects of group B. Results show greater increase in cardiac output and systemic peripheral resistance in obese on exposure to acute stress and delayed recovery to baseline values in comparison to non obese. © 2016, Indian Journal of Public Health Research and Development. All rights reserved.


Jain S.,Saraswathi Institute of Medical science
Indian Journal of Public Health Research and Development | Year: 2016

Obesity is a state of excessive deposition of fat in the body. Prehypertension is a state just before hypertension (SBP=120-139 mm Hg, DBP=80-89 mmHg) and very common in young adults with family history of hypertension. Hypertension is very like to develop in prehypertensive obese young adults if prevention strategies are not applied timely. Alternate nostril breathing (ANB, Anulom-Vilom) is one of the most popular pranayama yogic exercises. The present study was done to find out effect of 6 week training of alternate nostril breathing on cardiac output and systemic peripheral resistance in pre hypertensive obese young adults by using Impedance Cardiovasograph (Nivomon, L&T Medical’s). Sixty prehypertensive obese (BMI >30, SBP=120-139 mm Hg, DBP=80-89mmHg) male subjects, aged 17-25 years, participated voluntarily in the present study, Cardiac output, systemic peripheral resistance and other cardiovascular parameters were measured before and after 6 weeks training of Alternate Nostril Breathing (ANB) exercise of 15 minutes daily. Results showed significant decrease in all cardiovascular parameters after 6 weeks practice of ANB for 15 minutes daily. Decrease in Diastolic blood pressure (DBP), Systemic Peripheral Resistance (SVR) and Systemic Vascular Resistance Index (SVRI) was highly significant (p<0.01) while decrease in Systolic blood pressure (SBP), Heart rate (HR), Cardiac Output (CO), Stroke volume (SV), Cardiac Index (CI) and Stroke volume Index (SI) was less significant (p<0.05). © 2016, Indian Journal of Public Health Research and Development. All rights reserved.


Yadav S.P.S.,Pt. B.D. Sharma P.G.I.M.S. | Goel A.K.,Saraswathi Institute of Medical science
International Journal of Pediatric Otorhinolaryngology Extra | Year: 2010

Mucormycosis is a rare and life threatening fungal infection in children that occurs in association with immunocompromised states. Very few case reports of rhino-orbital mucormycosis have been documented in pediatric age group and most of these have been fatal. We report a case of mucormycosis in a child with renal disease who was managed with lipid complex amphotericin B coupled with surgical debridement. © 2008 Elsevier Ireland Ltd. All rights reserved.

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