Ramani V.K.,Sapthagiri Institute of Medical science |
Pattankar J.,Khaja Banda Nawaz Institute of Medical science |
Puttahonnappa S.K.,Indian National Institute of Animal Nutrition and Physiology
Journal of Clinical and Diagnostic Research | Year: 2016
Introduction: Among all illness, Acute Respiratory Infections (ARI) account for 30-60% of paediatric outpatient attendance and 20-30% of hospital admissions. Aim: To study the morbidity pattern of ARI among under-five-age group childrens and to assess the determinants there with. Materials and Methods: A longitudinal cohort study was conducted for a one year period, comprising a cumulative sample of 400 children from 3 urban slums of Gulbarga city. History of nasal discharge, cough, fever, sore throat, breathing difficulty, any discharge from ear alone or in combination, will be used in the recognition of an ARI episode. Respiratory rate >60/minute (<2 month infants), >50(2-11 months) and >40(1-5 years) in a child with cough, cold or fever singly or in combination are the criteria for recognition of pneumonia. Results: Out of the 400 surveyed, ARI was detected among 109 children giving an incidence of 27.25%. Among these, Upper Respiratory Tract Infection (URTI) was found among 19.25% and Lower Respiratory Tract Infection (LRTI) among 8%. ARI was observed among 38.04% of infants, 37.84% of 2-3-year-old children, 36.87% of boys, 40.43% of children born to illiterate father’s, 35.77% of SES class IV & 40.79% of SES class V, and 41.89% of children with family history of respiratory illness. All these data were found to be statistically significant. High rates of ARI were also observed among 41.36% of children living in households with firewood fuel usage, 35.04% of children with pets in the household, 34.82% of children with delayed milestones, 53.85% of children with grade IV and 66.67% of children with grade V malnutrition. More episodes occurred during winter months of the year (Oct – Jan). During the follow-up phase of study done on a cohort of 112 children for a period of one year, an attack rate of 3.27 episodes/child/year was observed. Conclusion: Community education programs should focus on addressing specific issues viz. identification of respiratory illness, simple case management, proper immunization practices, breast feeding of infants & nutrition of child and reduction of domestic air pollution. © 2016, Journal of Clinical and Diagnostic Research. All Rights Reserved.
Chaithra Rao. B.R.,Sapthagiri Institute of Medical science |
Ratkal J.,Lifeline Hospital |
Joshi R.,Lifeline Hospital
Journal of Clinical and Diagnostic Research | Year: 2015
Abnormalities in the closure of the intraembryonic portion of the allatoic lumen result in urachal abnormalities. Urachal remnant diseases are rare in adults. Malignant urachal neoplasms, like adenocarcinoma which may probably occur due to metaplasia of the transitional epithelium of the urachal remnant are very rare. Surgical excision of the urachus is needed. The imaging features of the urachal abnormalities are important for correct diagnosis and surgical management. © 2015, Journal of Clinical and Diagnostic Research. All rights reserved.
Vidhya R.,Sapthagiri Institute of Medical Science
International Journal of Pharma and Bio Sciences | Year: 2015
Nature has provided mankind with several plants which contain natural substances which cure diseases & promote health. Considering its medicinal property, extraction of oil from plant fruit materials of Terminalia chebula was used, as it proved to preserve the original qualities of the plant and also causes no degradation of the materials used. Steam Distillation process was used for the extraction of oil at lab scale using the available resources. The present study investigated, the phytochemical screening of T chebula extract, it revealed the presence of terpenoids, alkaloids, volatile acids and tannins. The antibacterial potential of fruit extract evaluated against clinical isolates showed the exhibition of antibacterial effect against all isolates. The antioxidant activity tested, showed a maximum inhibition in the range of 75-90% of 1mg/ml of extract and their IC50 value was found to be 620 μg/ml. The high content of total phenolic compound (440 μg GAE/mg of extract) revealed the antioxidant activity of the extract.
PubMed | Sapthagiri Institute of Medical science and Lifeline Hospital
Type: Journal Article | Journal: Journal of clinical and diagnostic research : JCDR | Year: 2015
Abnormalities in the closure of the intraembryonic portion of the allatoic lumen result in urachal abnormalities. Urachal remnant diseases are rare in adults. Malignant urachal neoplasms, like adenocarcinoma which may probably occur due to metaplasia of the transitional epithelium of the urachal remnant are very rare. Surgical excision of the urachus is needed. The imaging features of the urachal abnormalities are important for correct diagnosis and surgical management.
Sarmah P.,Sapthagiri Institute of Medical science |
Hanumanthappa A.R.,JJM Medical College |
Chandrappa N.R.,JJM Medical College
Journal of Pure and Applied Microbiology | Year: 2014
Dengue virus infection is transmitted by the Aedes aegyptii mosquito. It causes a spectrum of illnesses ranging from asymptomatic cases, mild dengue fever (DF) to severe complications like dengue hemorrhagic fever / dengue shock syndrome (DHF/ DSS). This viral infection is seen worldwide, with large number of cases in the South-East Asian countries, including, India This study was conducted to find the distribution of dengue virus infection and to study the clinical profile among the hospitalized patients. The study was conducted in the department of Microbiology of a tertiary care center for a year. After history taking and clinical examination blood samples were collected from 250 suspected dengue cases. These samples were subjected to ELISA to detect Dengue IgM antibodies. Patient's platelet count and hematocrit were also determined. Out of the 250 cases 155 (62%) were positive for IgM dengue antibodies. The age group of affected patients ranged from 1-20 years. Disease was distributed more in males. The monsoon and post-monsoon seasons accounted for majority of cases. The disease manifested as DF- 79%, DHF -17% and DSS - 4% cases. The various symptoms associated with disease were fever, headache, joint pain, retro-orbital pain, myalgia and backache. Decreased platelet count was seen only in 15% of the cases. Hematocrit was within normal range. Ours is an area endemic for dengue virus, with disease prevalent more in the young male children and adults. Severe forms of dengue are important causes of morbidity and mortality in the pediatric age group. Important public health measures must be taken during the monsoon and post-monsoon seasons to decrease this trend.
Chandra G.,MS Ramaiah Medical College |
Jayanth S.H.,MS Ramaiah Medical College |
Saralaya P.K.,MS Ramaiah Medical College |
Udaya Shankar B.S.,Sapthagiri Institute of Medical science |
Praveen S.,MS Ramaiah Medical College
Journal of South India Medicolegal Association | Year: 2014
Cut or Incised wounds to the neck are commonly homicidal or suicidal in manner and rarely accidental more so sustained in vehicular or industrial accidents. Opining the manner of death in cut throat injuries is always a challenge to the autopsy surgeon when death has resulted under suspicious circumstances. The characteristics of the wound with respect to its direction, depth, site, blood stain pattern, weapon, clothing, and scene visit help in opining the manner of death. One such case where an elderly individual found in a pool of blood with a neck injury at his work place is being discussed. Death occurred as a result of exsanguination caused by the injuries to major blood vessels of the neck. Although the cut in the neck initially suggested homicide, it was found to have occurred as a result of an accident after the autopsy and death scene investigation. © 2014 South India Medico-Legal Association. All rights reserved.
Desai K.N.P.,MS Ramaiah Medical College |
Roopakala M.S.,MS Ramaiah Medical College |
Silvia C.R.W.D.,Sapthagiri Institute of Medical science |
Kumar K.M.P.,MS Ramaiah Medical College
International Journal of Diabetes in Developing Countries | Year: 2012
The aim of the study was to assess the plasma fibrinogen levels in type 2 diabetes mellitus patients and to compare with that of healthy controls. To correlate plasma fibrinogen levels with blood pressure (BP), BMI (Body Mass Index) and HbA1c (Glycated hemoglobin) among diabetics and healthy controls. Blood samples were collected for Plasma fibrinogen levels and HbA1c from 30 diagnosed type 2 diabetes mellitus patients. Their BP and BMI were recorded. 30 age and sex matched healthy subjects were included as a control group. There was a rise in plasma fibrinogen levels in diabetics with BMI < 25 kg/m 2 as compared to controls of the same BMI group (P = 0.097). Also, there was a trend of raised plasma fibrinogen levels among male diabetics as compared to male control subjects (P = 0.079). However, there appears no such difference among female individuals. However, there was no significant correlation between fibrinogen levels, blood pressure and HbA1c both among controls and diabetic cases (P >0.05). Though there was a slight trend of increasing levels of plasma fibrinogen among diabetics as compared to controls. However, a significant positive correlation between BMI, male gender and increasing age with plasma fibrinogen was found. © 2012 Research Society for Study of Diabetes in India.
Hemavathi P.S.,Sapthagiri Institute of Medical science |
Shenoy P.,Sapthagiri Institute of Medical science |
Sharvani R.,Sapthagiri Institute of Medical science
Journal of Pure and Applied Microbiology | Year: 2015
Klebsiella species is an important pathogen responsible for various hospitalacquired infections. They are isolated from various sites in the hospital or from the health care workers. These hospital strains can be resistant to various antibiotics. They are also known to cause neonatal septicemia. A sudden increase in Klebsiella isolates from NICU prompted this study. Retrospective and prospective data were analyzed from the months of September 2013 to March 2014 i.e., before and after the outbreak. During that period a total of 249 blood culture samples from NICU were collected for analysis. Culture and sensitivity was performed for the isolates. Samples were also collected from the environment, water and health care personnel to identify the source.Out of the 249 blood samples 35 (14%) yielded bacterial growth on primary & secondary sub culture. The remaining 100 (86%) yielded no growth. Klebsiella species accounted for 29%, Coagulase Negative Staphylococci (CONS) for 37%, Enterococci 11 %, along with these various other bacteria were also isolated. Many of the Klebsiella strains were ESBL producers, and a clustering of cases was seen in the months of December 2013 and January 2014. Klebsiella was also isolated from the water sample used for humidification. The present study emphasizes the importance of good infection control practices and rationale use of antibiotics especially in high risk settings like the NICU.
Hemavathi,Sapthagiri Institute of Medical science |
Sarmah P.,Sapthagiri Institute of Medical science |
Ramesh D.H.,Vydehi Institute of Medical science
Journal of Clinical and Diagnostic Research | Year: 2012
Introduction: Tuberculosis (TB) is a global health problem. An early diagnosis and an effective treatment are essential to prevent the spread of infection and to reduce the disease burden. Though the causative bacterium for this disease was discovered in the eighteenth century, its diagnosis in the twenty-first century is still a dogma. Objectives: To compare of the rapid slide culture (RSC) method with the growth on Lowenstein Jensen (LJ) media and to know the sensitivity and specificity of the rapid slide culture method and the acid fast smear examination in comparison with the growth on the L J media. Materials and Methods: One early morning sputum sample was collected from 220 clinically suspected pulmonary tuberculosis cases. All the samples were subjected to three tests: 1. Zeihl Neelsen Staining 2. Rapid slide culture and 3. Culture on Lowenstein Jensen media and the results were compared. Results: Of the total 220 sputum samples which were tested by all the three methods, 51 samples (23.18%) were found to be smear positive, 75 (34.09%) were found to be positive by the RSC method, 81 (36.81%) were found to be positive by the LJ culture method and 38(17.27%) samples were found to be positive by all the three methods and 93 (42.27%) samples were found to be positive by any one method. 127 (57.72%) samples were negative by all the three tests The sensitivity of RSC in comparison with the LJ culture was 88.88% with a specificity of 97.8%, whereas the smear showed a sensitivity of 49.4% and a specificity of 92.1%. Discussion: The RSC method is rapid, sensitive and more specific than microscopy. Hence, this method can be adopted by any simple laboratory for the diagnosis of tuberculosis.
PubMed | Sapthagiri Institute of Medical science
Type: Journal Article | Journal: Asian journal of neurosurgery | Year: 2015
We report a case of a median nerve schwannoma, a rare type of a benign tumor of Schwann cells that presents as a palpable and painful mass on the flexor aspect of the forearm. Schwannomas of the median nerve make up 0.1-0.3% of all hand tumors. Symptoms are caused by an entrapment syndrome resulting from the growing tumor. Pain is the most common complaint of schwannomas. Imaging studies include computed tomography and magnetic resonance imaging and ultrasound. It is difficult to differentiate schwanommas from neurofibromas solely on the basis of a radiological investigation. Tumors of the median nerve are diagnostically challenging and median nerve schwannomas are rare. Diagnostic pearls are described to facilitate a more accurate and timely diagnosis. These characteristics include mobility, Tinels sign, S-100 histological staining, and Antoni patterns. With a correct diagnosis, the tumor can be extirpated with preservation of nerve function and a low risk of recurrence.